AC-DEVD-CHO
AC-DEVD-CHO Basic information
- Product Name:
- AC-DEVD-CHO
- Synonyms:
-
- Ac-DEVD-CHO,N-Acetyl-Asp-Glu-Val-Asp-al, >98%
- AC-DEVD-CHO?, >98%
- Caspase-3 Inhibitor I - CAS 169332-60-9 - Calbiochem
- N-ACETYL-L-ALPHA-ASPARTYL-L-ALPHA-GLUTAMYL-N-(2-CARBOXY-1-FORMYLETHYL)-L VALINAMIDE
- N-AC-ASP-GLU-VAL-ASP-CHO
- N-ACETYL-ASP-GLU-VAL-ASP-AL
- N-ACETYL-ASP-GLU-VAL-ASP-CHO (ALDEHYDE)
- CPP32/APOPAIN INHIBITOR
- CAS:
- 169332-60-9
- MF:
- C20H30N4O11
- MW:
- 502.47
- Product Categories:
-
- peptides
- Caspase 10
- Caspase 3
- Caspase 7
- Caspase 8
- Caspase Inhibitors
- Caspase Inhibitors and Substrates
- Peptides and Proteins
- Peptides for Cell Biology
- Protease Inhibitor Specificity Index
- Protease Inhibitors
- A to C
- A-AM
- Aldehydes
- and Substrates
- Apoptosis and Cell Cycle
- Apoptosis Enzymes
- Application Index
- Bioactive Small Molecules
- Biochemicals and Reagents
- Building Blocks
- C13-C60
- Carbonyl Compounds
- Caspases
- Cell Biology
- Cell Signaling and Neuroscience
- Cell Signaling Enzymes
- Chemical Synthesis
- Enzyme Inhibitors
- Enzyme Inhibitors by Enzyme
- Enzymes
- Inhibitors
- Organic Building Blocks
- Pepetides
- Mol File:
- 169332-60-9.mol
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AC-DEVD-CHO Chemical Properties
- Boiling point:
- 1021.1±65.0 °C(Predicted)
- Density
- 1.374±0.06 g/cm3(Predicted)
- RTECS
- EK7643000
- storage temp.
- -20°C
- solubility
- H2O: 1 mg/mL
- form
- powder
- pka
- 4.19±0.10(Predicted)
- color
- white
- Sensitive
- Moisture Sensitive
MSDS
- Language:English Provider:SigmaAldrich
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AC-DEVD-CHO Usage And Synthesis
Uses
Reversible inhibitor of interleukin-1beta converting enzyme (ICE); also inhibits caspase-3 cleavage of poly(ADP-ribose) polymerase
Uses
N-Acetyl-Asp-Glu-Val-Asp-al has been used as a caspase inhibitor in muscle samples, smooth muscle cells and Jurkat T-cells.
Definition
ChEBI: A tetrapeptide consisting of two L-aspartic acid residues, an L-glutamyl residue and an L-valine residue with an acetyl group at the N-terminal and with the C-terminal carboxy group reduced to an aldehyde. It is an inhibitor of caspase-3/7.
General Description
N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) is a tetrapeptide with N-terminal acetylation and C-terminal aldehyde conjugation.
Biochem/physiol Actions
N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) aids in the recovery of stunned myocardium by its caspase inhibition functionality.
AC-DEVD-CHOSupplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Beijing Ouhe Technology Co., Ltd
- Tel
- 010-82967028 13552068683
- 2355560935@qq.com
VDM Biochemicals
- Tel
- 0330-2528181
- sales@vdmbio.com
Syntechem Co.,Ltd
- Tel
- info@syntechem.com
Dalian Meilun Biotech Co., Ltd.
- Tel
- 0411-62910999 13889544652
- meilunui@163.com
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AC-DEVD-CHO(169332-60-9)Related Product Information
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- AC-ASP-GLU-VAL-ASP-CHO TFA