Sulcotrione Chemical Properties

Melting point:

139°

Boiling point:

574.5±50.0 °C(Predicted)

Density 

1.428±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

pka

3.22±0.50(Predicted)

color 

White to off-white

Merck 

13,8979

BRN 

8155739

InChIKey

PQTBTIFWAXVEPB-UHFFFAOYSA-N

EPA Substance Registry System

1,3-Cyclohexanedione, 2-[2-chloro-4-(methylsulfonyl)benzoyl]- (99105-77-8)

Safety Information

Hazard Codes 

Xi,N,Xn

Risk Statements 

43-50/53-48/22-63

Safety Statements 

36/37-61-60-22

RIDADR 

UN 3077 9 / PGIII

WGK Germany 

2

HS Code 

29309090

Sulcotrione Usage And Synthesis

Uses

Herbicide.

Definition

ChEBI: An aromatic ketone that is cyclohexane-1,3-dione substituted by a 2-chloro-4-(methylsulfonyl)benzoyl group at position 2.

Pharmacology

Mode of action studies with sulcotrione first led to the identity of HPPD as a highly effective herbicide target site. Early observations showed that a related compound caused increased levels of tyrosine in the plasma and urine of treated rats (12). Further studies showed that one of the tyrosine catabolism enzymes, 4-hydroxypyruvate dioxygenase, was inhibited by cyclohexanediones (13,14)—this enzyme being required for the formation of quinones, such as plastoquinone in plants (12,15,16). Inhibition results in the perturbation of carotenoid synthesis and inhibition of photosynthetic electron transport (16).

Metabolism

Sulcotrione is readily absorbed through the leaves and via the roots. In the soil, metabolism involves ring opening of the cyclohexanedione, eventually to give the corresponding benzoic acid (17) and, finally, CO2 (8).
In the soil, the half-life of sulcotrione can vary considerably (between 15 days in loamy sand and 72 days in fine loam), depending on a number of factors, especially the soil organic matter content (18,19).

Sulcotrione(99105-77-8)Related Product Information

• 1,3-Cyclohexanedione
• DL-α-Tocopherol
• 4-(Diethylamino)salicylaldehyde
• Epichlorohydrin
• Benzoyl chloride
• Diphenyl sulfone
• Phenyl sulfoxide
• 5-Chlorovaleric acid
• Pralmorelin
• Benzoyl peroxide
• Diphenolic acid
• 4,4'-Diaminodiphenylsulfone
• 2-Chloro-4-methylsulphonylbenzoic acid
• 4,4'-Dichlorodiphenyl sulfone
• 2-ACETYLCYCLOHEXANONE
• 2-BENZYLCYCLOHEXANONE
• 2-ACETYL-1,3-CYCLOHEXANEDIONE
• 4-Methylsulphonylacetophenone