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HEPPSO

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HEPPSO Basic information

Product Name:
HEPPSO
Synonyms:
  • 4-(2-hydroxyethyl)piperazine-1-(2-hydr.prop.sulf.ac.)1h2o
  • beta-hydroxy-4-(2-hydroxyethyl)-1-piperazinepropanesulfonicaci
  • HEPPSO Buffer
  • β-Hydroxy-4-(2-hydroxyethyl)-1-piperazinepropanesulfonic acid monohydrate, N-(2-Hydroxyethyl)piperazine-Nμ-(2-hydroxypropanesulfonic acid), 4-(2-Hydroxyethyl)piperazine-1-(2-hydroxypropanesulfonic acid) monohydrate
  • 4-(2-Hydroxyethyl)piperazine-1-(2-hydroxypropanesulfonic acid) Hydrate hydrate
  • HEPPSO Hydrate
  • 2-Hydroxy-3-(4-(2-hydroxyethyl)-1-piperazinyl)propane-1-sulfonic acid
  • 2-Hydroxy-3-[4-(2-hydroxyethyl)-1-piperazinyl]propane-1-sulfonic acid
CAS:
68399-78-0
MF:
C9H20N2O5S
MW:
268.33
EINECS:
269-990-1
Product Categories:
  • Buffer
  • Biochemistry
  • Pharmaceutical Intermediates
  • Good's Buffers
Mol File:
68399-78-0.mol
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HEPPSO Chemical Properties

Melting point:
158-160°C
Density 
1.382±0.06 g/cm3(Predicted)
Water Solubility 
almost transparency in Water
pka
1.10±0.50(Predicted)
form 
Liquid
color 
White to Almost white
InChI
InChI=1S/C9H20N2O5S/c12-6-5-10-1-3-11(4-2-10)7-9(13)8-17(14,15)16/h9,12-13H,1-8H2,(H,14,15,16)
InChIKey
GIZQLVPDAOBAFN-UHFFFAOYSA-N
SMILES
N1(CCN(CCO)CC1)CC(O)CS(=O)(=O)O
CAS DataBase Reference
68399-78-0(CAS DataBase Reference)
EPA Substance Registry System
1-Piperazinepropanesulfonic acid, .beta.-hydroxy-4-(2-hydroxyethyl)- (68399-78-0)
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Safety Information

Hazard Codes 
T,Xi
Risk Statements 
25-36/37/38
Safety Statements 
26-36-45-24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
29335995

MSDS

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HEPPSO Usage And Synthesis

Chemical Properties

HEPPSO is a white solid.Solubility: H2O: 250 mg/mL (931.69 mM; Need ultrasonic); DMSO: 250 mg/mL (931.69 mM; Need ultrasonic)

Uses

HEPPSO shows no toxicity for crustaceans with which it has been studied and has been deemed suitable for toxicological studies. As an zwitterionic biological buffer, it often used in biological and biochemical research. It could used as an ampholytic separator to create a pH gradient in isoelectric focusing. HEPPSO is able to form radicals and is thus not suitable for redox reactions. It could forms a complex with Cu(II) ions so stability constants and concentrations should be taken into consideration when using this buffer in a solution containing copper ions. Although HEPPSO binds to coppers ions, it is still suitable for use as the bicinchoninic acid (BCA) assay. Diminished protein-induced color development can be accounted for or even eliminated through precipitating protein prior to reaction with bicinchoninic acid.

Uses

HEPPSO is a zwitterionic buffer used in GMP-manufacturing of advanced therapy medication products.

Definition

ChEBI: HEPPSO is a N-(2-hydroxyethyl)piperazine and a N-(sulfoalkyl)piperazine.

HEPPSOSupplier

Suzhou Genemill Biotechnology Co.,Ltd Gold
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0512-65917170 17766001019;
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J & K SCIENTIFIC LTD.
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
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BeiJing Hwrk Chemicals Limted
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0757-86329057 18934348241
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sales4.gd@hwrkchemical.com