ETHYL MANDELATE Chemical Properties

Melting point:

35.5°C

alpha 

[α]D20 -0.1～+0.2° (neat)

Boiling point:

253-255 °C(lit.)

Density 

1.115 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.512(lit.)

Flash point:

>230 °F

storage temp. 

Refrigerator

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

form 

Oil

color 

Colourless

CAS DataBase Reference

4358-88-7(CAS DataBase Reference)

Safety Information

Safety Statements 

24/25

WGK Germany 

2

RTECS 

OO7397000

HS Code 

29172090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

ETHYL MANDELATE Usage And Synthesis

Chemical Properties

Appearance :white solid or liquid

Uses

Ethyl Mandelate is used as a reagent in the synthesis of several organic compounds including that of volatile methylsiloxanes which have the potential to be a more environmentally sustainable alternative as solvents in chemical synthesis to non-polar organic solvents. It was found to act as a substrate for (S)-mandelate dehydrogenase which is a flavin mononucleotide dependent enzyme that oxidises (S)-mandelate to benzoylformate.

Definition

ChEBI: Ethyl hydroxy(phenyl)acetate is the ethyl ester of mandelic acid. It is an ethyl ester and a secondary alcohol. It is functionally related to a mandelic acid.

Synthesis Reference(s)

Journal of the American Chemical Society, 107, p. 3981, 1985 DOI: 10.1021/ja00299a038
The Journal of Organic Chemistry, 49, p. 3241, 1984 DOI: 10.1021/jo00191a048

ETHYL MANDELATE(4358-88-7)Related Product Information

• Benactyzine
• zR{-(-)-Ethyl mandelate,(R)-(-)-Ethyl Mandelate
• (S)-(+)-Ethyl Mandelate
• CYCLANDELATE
• Bromopropylate
• Homatropine Hydrobromide
• ETHYL BENZILATE
• BENACTYZINE HYDROCHLORIDE
• Anisodine hydrobromide
• Oxyphenonium bromide
• CHLOROBENZILATE
• CHLOROPROPYLATE
• HOMATROPINE
• HOMATROPINE HYDROCHLORIDE
• ETHYL 4-HYDROXYMANDELATE
• Clidinium bromide
• Oxybutynin hydrochloride
• HOMATROPINE METHYL BROMIDE