2-Methyl-3-trifluoromethylaniline Chemical Properties

Melting point:

38-42 °C(lit.)

Boiling point:

62-64°C 4mm

Density 

1.237±0.06 g/cm3(Predicted)

Flash point:

>210 °F

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

form 

Crystalline Powder

pka

3.23±0.10(Predicted)

color 

White

BRN 

2832865

InChI

InChI=1S/C8H8F3N/c1-5-6(8(9,10)11)3-2-4-7(5)12/h2-4H,12H2,1H3

InChIKey

TWLDBACVSHADLI-UHFFFAOYSA-N

SMILES

C1(N)=CC=CC(C(F)(F)F)=C1C

CAS DataBase Reference

54396-44-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,T,T+

Risk Statements 

36/37/38-26/27/28

Safety Statements 

26-36-24/25

RIDADR 

2811

WGK Germany 

3

Hazard Note 

Toxic

HazardClass 

IRRITANT

HazardClass 

6.1

HS Code 

29214990

MSDS

• Language:English Provider:3-Amino-2-methylbenzotrifluoride
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Methyl-3-trifluoromethylaniline Usage And Synthesis

Chemical Properties

White crystalline powder

Uses

2-Methyl-3-trifluoromethylaniline is a reactant in the synthesis of methylguanidine derivatives as prospective PET radioligands for the open channel of the NMDA receptor, linked to Alzheimer’s, epilepsy and other neurodegenerative disorders.

General Description

2-Methyl-3-(trifluoromethyl)aniline belongs to the trifluoromethylbenzene series.

2-Methyl-3-trifluoromethylaniline (54396-44-0)Related Product Information

• 4-(Trifluoromethoxy)aniline
• N,N-Dimethyl-1,4-phenylenediamine
• N,N-Dimethylaniline
• Kresoxim-methyl
• Methyl acrylate
• Methyl acetate
• (Trifluoromethyl)trimethylsilane
• o-Toluidine
• Thiophanate-methyl
• 3-Aminophenol
• Tris(hydroxymethyl)aminomethane
• Bensulfuron methyl
• Methylparaben
• 3-Aminobenzotrifluoride
• ALTRENOGEST
• 6-Aminocaproic acid
• Glycine
• 3,3',5,5'-Tetramethylbenzidine dihydrochloride