Basic information Safety Supplier Related

Hexamethyleneimine

Basic information Safety Supplier Related

Hexamethyleneimine Basic information

Product Name:
Hexamethyleneimine
Synonyms:
  • g0
  • hexahydro-1h-azepin
  • Hexahydroazapine
  • G 0
  • HEXAMETHYLENIMINE
  • HEXAMETHYLENEIMINE
  • HMI
  • HOMOPIPERIDINE
CAS:
111-49-9
MF:
C6H13N
MW:
99.17
EINECS:
203-875-9
Product Categories:
  • Heterocycles
  • Impurities
  • Building Blocks
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Homopiperidines
  • Nitrogen cyclic compounds
Mol File:
111-49-9.mol
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Hexamethyleneimine Chemical Properties

Melting point:
-37°C
Boiling point:
138 °C749 mm Hg(lit.)
Density 
0.88 g/mL at 25 °C(lit.)
vapor pressure 
7.4 mm Hg ( 21.1 °C)
refractive index 
n20/D 1.466(lit.)
Flash point:
65 °F
storage temp. 
Poison room
form 
Liquid
pka
pK1:11.07 (25°C)
color 
Clear colorless to light yellow
Odor
Ammonia-like.
explosive limit
1.6-9.9%(V)
Water Solubility 
soluble
BRN 
1084
LogP
1.7
CAS DataBase Reference
111-49-9(CAS DataBase Reference)
NIST Chemistry Reference
1H-Azepine, hexahydro-(111-49-9)
EPA Substance Registry System
1H-Azepine, hexahydro- (111-49-9)
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Safety Information

Hazard Codes 
T,T+,F
Risk Statements 
10-20-25-34-28-11
Safety Statements 
26-36/37/39-45-28A-16-1
RIDADR 
UN 2493 3/PG 2
WGK Germany 
3
RTECS 
CM3150000
Autoignition Temperature
255 °C
TSCA 
Yes
HS Code 
2933 99 80
HazardClass 
3
PackingGroup 
II
Hazardous Substances Data
111-49-9(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 410 mg/kg

MSDS

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Hexamethyleneimine Usage And Synthesis

Chemical Properties

clear colorless to light yellow liquid

Uses

A degradation product of herbicide Molinate in pot soil and rice plants.

Uses

Hexamethyleneimine is used as a pharmaceutical product and raw material for rubber products. It is also used as a intermediate for agrochemicals, zeolites, dyes , inks, rubber chemicals, textile chemicals, corrosion inhibitors, ore flotation.

Definition

ChEBI: An azacycloalkane that is cycloheptane in which one of the carbon atoms is replaced by a nitrogen atom.

General Description

A colorless liquid with an ammonia-like odor. Flash point 65°F. Toxic by ingestion. Corrosive to metals and tissue. Combustion produces toxic oxides of nitrogen.

Air & Water Reactions

Highly flammable. Soluble in water.

Reactivity Profile

Hexamethyleneimine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.

Hazard

Toxic by ingestion, strong irritant to tissue.

Health Hazard

Inhalation of vapor irritates respiratory tract; high concentrations may cause disturbance of the central nervous system. Ingestion causes burns of mouth and stomach. Contact with concentrated vapor may cause severe eye injury. Contact with liquid causes burns of eyes and skin.

Flammability and Explosibility

Highlyflammable

Chemical Reactivity

Reactivity with Water No reaction; Reactivity with Common Materials: No reactions; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Purification Methods

Purify azepane by dissolving in Et2O and adding ethanolic HCl until all the base separates as the white hydrochloride, filter, wash with Et2O and dry it (m 236o). The salt is dissolved in the minimum volume of H2O and basified to pH ~ 14 with 10N KOH. The solution is extracted with Et2O, the extract is dried over KOH, evaporated and distilled. The free base is a FLAMMABLE and TOXIC liquid, and best kept as the salt. The nitrate has m 120-123o, the picrate has m 145-147o, and the tosylate has m 76.5o (ligroin). [Müller & Sauerwald Monatsh Chem 48 727 1027, Hjelt & Agback Acta Chem Scand 18 194 1964, Beilstein 20 II 1406, 20 III/IV 1406, 20/4 V 3.]

Hexamethyleneimine Preparation Products And Raw materials

Preparation Products

Raw materials

HexamethyleneimineSupplier