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4-Ethynylpyridine hydrochloride

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4-Ethynylpyridine hydrochloride Basic information

Product Name:
4-Ethynylpyridine hydrochloride
Synonyms:
  • 4-Ethynylpyridine HCl
  • 4-Ethynylpyridine hychloride
  • 4-Ethynylpyridine hydrochloride
  • 4-pyridylacetylene HCl
  • REF DUPL: 4-pyridylacetylene HCl
  • 4-Ethynylpyridinehychloride salt
  • 4-EthynyL
  • pyridine hydrochL
CAS:
352530-29-1
MF:
C7H6ClN
MW:
139.58
EINECS:
627-680-7
Product Categories:
  • Heterocycle-Pyridine series
  • C7 and C8
  • Heterocyclic Compounds
  • Heterocyclic Building Blocks
  • Pyridines
Mol File:
352530-29-1.mol
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4-Ethynylpyridine hydrochloride Chemical Properties

Melting point:
150 °C (dec.) (lit.)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
color 
Yellow to Brown to Dark green
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29333999
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4-Ethynylpyridine hydrochloride Usage And Synthesis

Uses

4-Ethynylpyridine hydrochloride may be used in the preparation of the following 2-methyl-6-(phenylethynyl)pyridine (MPEP) analogs:

  • 1,4-bis(pyridin-4-ylethynyl)benzene
  • 4-((5,5-dimethyl-1,3,2-dioxaborinan-2-yl)ethynyl)pyridyl
  • 4-((3-iodophenyl)ethynyl)pyridine
  • 4-((4-iodophenyl)ethynyl)pyridine
  • 1,4-di(pyridine-4-yl)buta-1,3-diyne

It may also be used in the preparation of:
  • (rac)-2,8-bis(4-pyridylethynyl)-4,10-dimethyl-5,11-methano-6H,12H-dibenzo[b,f][1,5]diazocine, a Tr?ger′s base derived bis(pyridyl) ligand
  • (2RS,6RS)-2-(4-methoxyphenyl)-6-(2-(4-(pyridin-4-yl)-1H-1,2,3-triazol-1-yl)ethyl)dihydro-2H-pyran-4(3H)-one, a substituted tetrahydropyrone
  • BINOL (1,1′-bi-2-naphthol)-based bis(4-pyridyl) ligands

General Description

4-Ethynylpyridine hydrochloride acts as a ligand for the synthesis of various metallic complexes.

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