esculentoside H Chemical Properties

Boiling point:

1042.8±65.0 °C(Predicted)

Density 

1.48±0.1 g/cm3(Predicted)

storage temp. 

4°C, protect from light

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

Powder

pka

12.52±0.70(Predicted)

color 

White to off-white

esculentoside H Usage And Synthesis

Uses

Esculentoside H (EsH) is a saponin isolated from the root extract of perennial plant Phytolacca esculenta[1]. Esculentoside H (EH) has anti-tumor activity, the mechanism is related to the capacity for TNFrelease[2]. Esculentoside H (EsH) suppresses colon cancer cell migration through blockage of the JNK1/2 and NF-κB signaling-mediated matrix metalloproteinases-9 (MMP-9) expression[1].

References

[1] Ha SH, et al. Esculentoside H inhibits colon cancer cell migration and growth through suppression of MMP-9 gene expression via NF-kB signaling pathway. J Cell Biochem. 2019 Jun;120(6):9810-9819. DOI:10.1002/jcb.28261
[2] Hu ZL, et al. Effect of esculentoside H on release of tumor necrosis factor from mouse peritoneal macrophages. Zhongguo Yao Li Xue Bao. 1993 Nov;14(6):550-2. PMID:8010057

esculentoside H(66656-92-6)Related Product Information

• Deslanoside
• Carboxyatractyloside
• Pachymic acid
• Madecassoside
• ALLEOSIDE A
• dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate
• ESCULENTOSIDE C
• roburic acid
• Poricoic acid A(F)
• ESCULENTOSIDE D
• Esculentoside A
• Phytolaccagenin
• ASIAN GINSENG
• SOLASODINE
• Asiaticoside B
• Terrestrosin K
• Terrestrosin D
• Sarsasapogenin 3-O-β-D-galactopyranosid