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1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodiuM salt)

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1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodiuM salt) Basic information

Product Name:
1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodiuM salt)
Synonyms:
  • 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE (SODIUM SALT);18:1 PS (DOPS)
  • 18:1 PS (DOPS)
  • 1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)
  • sodium O-(((R)-2,3-bis(oleoyloxy)propoxy)oxidophosphoryl)-L-serinate
  • (2S)-2-azaniumyl-3-[[(2R)-2,3-bis[[(Z)-octadec-9-enoyl]oxy]propoxy]-oxidophosphoryl]oxypropanoate
  • 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium
  • 1,2-Dioctadecenoyl-sn-glycero-3-Phosphoserine
  • Inhibitor,1,2 Dioleoyl sn glycero 3 phospho L serine sodium,DOPE,inhibit,1,2Dioleoylsnglycero3phosphoLserine sodium,DOPC
CAS:
90693-88-2
MF:
C42H79NNaO10P
MW:
812.05
Mol File:
90693-88-2.mol
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1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodiuM salt) Chemical Properties

storage temp. 
Store at -20°C
solubility 
Chloroform: 10 mg/ml
form 
A crystalline solid
color 
Light yellow to orange
InChIKey
RRLDZFIFYLDDLI-OLZOWLLTNA-N
SMILES
[C@H](COC(=O)CCCCCCC/C=C\CCCCCCCC)(OC(=O)CCCCCCC/C=C\CCCCCCCC)COP(O)(=O)OC[C@H](N)C(=O)O.[NaH] |&1:0,49,r|
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1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodiuM salt) Usage And Synthesis

Description

1,2-Dioleoyl-sn-glycero-3-PS (DOPS) is a phospholipid containing oleic acid (Item Nos. 90260 | 24659) at the sn-1 and sn-2 positions, respectively. Nanovesicles composed of DOPS and the lysosomal protein saposin C (SapC) are cytotoxic to SK-MEL-28 cells in vitro and decrease tumor volume in a squamous cell carcinoma mouse xenograft model. DOPS has been used in the formation of unilamellar vesicles to study the effect of curvature on membrane structure and in the formation of supported lipid bilayers to study the effects of various support materials on lipid redistribution between membrane leaflets.

Uses

1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodiuM salt) is a lipid being studied in the assembly and long-term stability of solid supported lipid bilayers from artificial and natural lipid mixtures.

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