Basic information Safety Supplier Related

Hydroxy-PEG4-CH2CO2Me

Basic information Safety Supplier Related

Hydroxy-PEG4-CH2CO2Me Basic information

Product Name:
Hydroxy-PEG4-CH2CO2Me
Synonyms:
  • Hydroxy-PEG4-CH2CO2Me
  • 3,6,9,12-Tetraoxatetradecanoic acid, 14-hydroxy-, methyl ester
  • Hydroxy-PEG4-methyl acetate
  • HO-PEG4-CH2COOMe
  • HO-PEG4-CH2COOMe/3,6,9,12-Tetraoxatetradecanoic acid, 14-hydroxy-, methyl ester
  • methyl 2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]acetate
  • Methyl 14-hydroxy-3,6,9,12-tetraoxatetradecan-1-oate
CAS:
77303-64-1
MF:
C11H22O7
MW:
266.29
Mol File:
77303-64-1.mol
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Hydroxy-PEG4-CH2CO2Me Chemical Properties

Boiling point:
120 °C(Press: 0.001 Torr)
Density 
1.125±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
form 
Liquid
pka
14.36±0.10(Predicted)
color 
Colorless to light yellow
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Hydroxy-PEG4-CH2CO2Me Usage And Synthesis

Uses

Hydroxy-PEG4-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Hydroxy-PEG4-CH2CO2MeSupplier

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Shanghai Haohong Pharmaceutical Co., Ltd.
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