Hydroxy-PEG2-CH2CO2H Chemical Properties

Boiling point:

343.4±22.0 °C(Predicted)

Density 

1.239±0.06 g/cm3(Predicted)

solubility 

Chloroform (Slightly), DMSO (Slightly)

pka

3.39±0.10(Predicted)

form 

Oil

color 

Colourless

Safety Information

HS Code 

2942000090

Hydroxy-PEG2-CH2CO2H Usage And Synthesis

Description

Hydroxy-PEG2-CH2CO2H sodium salt is a PEG linker containing a hydroxyl group with a terminal carboxylic acid (as sodium salt form). The free acid form is not stable due to the reaction of OH with PEG-COOH group to form polymer. The sodium salt form is stable for storage and shipping. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

Uses

Hydroxy-PEG2-CH2CO2H can be used to prepare cyclin dependent kinase to treat cancer.

Hydroxy-PEG2-CH2CO2H(51951-04-3)Related Product Information

• PEG4-tert-butyl acetate
• Hydroxy-PEG3-t-butyl acetate
• Hydroxy-PEG5-t-butyl acetate
• Hydroxy-PEG1-CH2CO2tBu
• Hydroxy-PEG6-CH2CO2tBu
• HO-PEG5-CH2COOtBu
• HS-PEG5-CH2CH2COOH
• Hydroxy-PEG1-methyl ester
• Hydroxy-PEG4-CH2CO2Me
• HO-PEG6-CH2COOH
• HS-PEG4-CH2CH2COOH
• HO-PEG3-CH2COOH
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• DBCO-Acid
• disulfo-ICG-carboxylic acid(tri-sulfo-cy7.5 COOH)
• Thiol-PEG3-acid