2-Chloro-4-cyanopyridine Chemical Properties

Melting point:

69-73 °C(lit.)

Boiling point:

104-106°C 15mm

Density 

1.33±0.1 g/cm3(Predicted)

Flash point:

104-106°C/15mm

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

soluble in Methanol

form 

powder to crystal

pka

-1.60±0.10(Predicted)

color 

White to Almost white

BRN 

113927

InChI

InChI=1S/C6H3ClN2/c7-6-3-5(4-8)1-2-9-6/h1-3H

InChIKey

QRXBTPFMCTXCRD-UHFFFAOYSA-N

SMILES

C1(Cl)=NC=CC(C#N)=C1

CAS DataBase Reference

33252-30-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

26-36-36/37/39-36/37

RIDADR 

3276

WGK Germany 

3

Hazard Note 

Irritant

HazardClass 

6.1

PackingGroup 

III

HS Code 

29333990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Chloro-4-cyanopyridine Usage And Synthesis

Chemical Properties

White to off-white solid

Uses

2-Chloro-4-cyanopyridine is an intermediate used to prepare pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2). It is also used to synthesize pyridinyl-tetrazoles as scaffold to identify matrix MMP-13 inhibitors for treatment of osteoarthritis.

2-Chloro-4-cyanopyridine(33252-30-1)Related Product Information

• 2-Chloro-4-picoline
• 2-Chloro-5-chloromethylpyridine
• ETHYL 2-CYANOACRYLATE
• 4-Cyanopyridine
• Pentachloropyridine
• Clopidol
• MCPA SODIUM
• Methylene dithiocyanate
• 2,6-Lutidine
• 2,6-Dichloroisonicotinonitrile
• 3-CHLORO-4-CYANOPYRIDINE,3-Chloro-4-cyanopyridine ,98%
• 2-Chloro-3-cyanopyridine 97%,2-CHLORO-3-CYANOPYRIDINE
• Difluorochloromethane
• 2,6-Dichloronicotinonitrile
• 2-CHLORO-3-CYANOPYRIDINE-4-BORONIC ACID
• 2-CHLORO-6-CYANOPYRIDINE,P-1002-Chloro-6-Cyanopyridine,6-CHLORO-2-CYANOPYRIDINE
• 4-CHLORO-2-CYANOPYRIDINE,2-Cyano-4-chloropyridine, 4-Chloro-2-cyanopyridine, 4-Chloropicolinonitrile
• 2-chloro-5-cyanopyridine