1,4-Dihydroxyanthraquinone Chemical Properties

Melting point:

198-199 °C(lit.)

Boiling point:

450 °C

Density 

1.3032 (rough estimate)

vapor density 

8.3 (vs air)

vapor pressure 

1 mm Hg ( 196.7 °C)

refractive index 

1.5430 (estimate)

Flash point:

222 °C

storage temp. 

Store below +30°C.

solubility 

<1g/l

form 

powder

pka

pK (18°) 9.51

Colour Index 

58050

color 

red-brown

Water Solubility 

<1 g/L (20 ºC)

Merck 

14,8064

BRN 

1914036

InChIKey

GUEIZVNYDFNHJU-UHFFFAOYSA-N

CAS DataBase Reference

81-64-1(CAS DataBase Reference)

NIST Chemistry Reference

9,10-Anthracenedione, 1,4-dihydroxy-(81-64-1)

EPA Substance Registry System

Quinizarin (81-64-1)

Safety Information

Hazard Codes 

Xi,N

Risk Statements 

36/37/38-43-50/53

Safety Statements 

22-24/25-36/37-26-61-60

RIDADR 

UN 3077 9 / PGIII

WGK Germany 

2

RTECS 

CB6600000

TSCA 

Yes

HS Code 

2914 69 80

PackingGroup 

III

Hazardous Substances Data

81-64-1(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: > 5000 mg/kg

MSDS

• Language:English Provider:1,4-Dihydroxy-9,10-anthracenedione
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

1,4-Dihydroxyanthraquinone Usage And Synthesis

Chemical Properties

orange to red-brown crystalline powder

Uses

Antioxidant in synthetic lubricants, dyes.

Uses

1,4-Dihydroxyanthraquinone, also known as quinizarin, is of great importance in manufacturing disperse, acid, and vat dyes.

Definition

ChEBI: A dihydroxyanthraquinone having the two hydroxy substituents at the 1- and 4-positions; formally derived from anthraquinone by replacement of two hydrogen atoms by hydroxy groups

Synthesis Reference(s)

Synthesis, p. 633, 1974 DOI: 10.1055/s-1974-23387
Tetrahedron Letters, 28, p. 1533, 1987 DOI: 10.1016/S0040-4039(01)81035-2

Safety Profile

Poison by intravenous route. Moderately toxic by intraperitoneal route. Mutation data reported. An eye irritant. A weak allergen. When heated todecomposition it emits acrid smoke and irritating fumes.

Purification Methods

Crystallise quinizarin from glacial acetic acid. [Beilstein 8 H 450, 8 IV 3260.]

1,4-Dihydroxyanthraquinone(81-64-1)Related Product Information

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