3-Chlorophenol Chemical Properties

Melting point:

31-34 °C (lit.)

Boiling point:

214 °C (lit.)

Density 

1.218 g/mL at 25 °C (lit.)

vapor pressure 

1 hPa (44 °C)

refractive index 

n20/D 1.563(lit.)

Flash point:

>230 °F

storage temp. 

Store below +30°C.

solubility 

Soluble in ethanol and ether.

pka

8.85(at 25℃)

form 

Liquid After Melting

color 

Clear yellow to brownish

Odor

distinct phenol-like odor

PH

3.5 (27.7g/l, H2O, 20℃)

Water Solubility 

27.7 g/L (20 ºC)

Merck 

14,2154

BRN 

1634401

Stability:

Stable. Combustible. Incompatible with acid chlorides, oxidizing agents, acid anhydrides. Discolours in air.

CAS DataBase Reference

108-43-0(CAS DataBase Reference)

NIST Chemistry Reference

Phenol, 3-chloro-(108-43-0)

EPA Substance Registry System

m-Chlorophenol (108-43-0)

Safety Information

Hazard Codes 

Xn,N

Risk Statements 

20/21/22-51/53

Safety Statements 

28-61-28A

RIDADR 

UN 2020 6.1/PG 3

WGK Germany 

2

RTECS 

SK2450000

F 

9

Autoignition Temperature

>600 °C

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29081000

Hazardous Substances Data

108-43-0(Hazardous Substances Data)

Toxicity

LD50 orally in rats: 0.57 g/kg (Deichmann)

MSDS

• Language:English Provider:3-Chlorophenol
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3-Chlorophenol Usage And Synthesis

Chemical Properties

White to light yellow crystal.

Chemical Properties

All isomers have a characteristic odor.

Uses

3-Chlorophenol is a halophenol with antifungal activity. 3-Chlorophenol is commonly used as a building block in the preparation of variety of biologically active compounds. Studies suggest that 3-Chlo rophenol can be used in the regeneration of vegetal activated carbons.

Uses

3-Chlorophenol is widely used in the pharmaceutical, dyes and organic synthesis industry. It is an important intermediate in the synthesis of chemicals.

Uses

3-Chlorophenol is generally used in building various polycyclic aromatic systems. It is also employed in palladium-catalyzed coupling reactions to synthesize aryl intermediates in synthetic organic chemistry.

Definition

ChEBI: 3-chlorophenol is a monochlorophenol carrying the chloro substituent at position 3.

General Description

White crystals with an odor of phenol. Sinks in and slowly dissolves in water.

Air & Water Reactions

Discolors on exposure to air. Water soluble

Reactivity Profile

3-Chlorophenol is incompatible with acid chlorides, acid anhydrides and oxidizing agents .

Hazard

Toxic by skin absorption, inhalation, or ingestion.

Fire Hazard

3-Chlorophenol is probably combustible.

Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. Questionable carcinogen with experimental tumorigenic data by skin contact. Mutation data reported. Flammable or combustible liquid. When heated to decomposition it emits toxic fumes of Cl-. See also CHLOROPHENOLS.

Potential Exposure

Monochlorophenols are used in the manufacture of fungicides, slimicides, bactericides, pesticides, herbicides, disinfectants, wood and glue preservatives; in the production of phenolic resins; in the extraction of certain minerals from coal; as a denaturant for ethanol; as an antiseptic; as a disinfectant, and others.

Shipping

UN 2020 (solid); UN2021 (liquid) Chlorophenols, solid and liquid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Purification Methods

It could not be obtained solid by crystallisation from pet ether. It is best purified by distillation under reduced pressure. [Beilstein 6 IV 810.]

Incompatibilities

May form explosive mixture with air. Contact with oxidizing agents can cause fire and explosion hazard. Heat produces hydrogen chloride and chlorine. Corrosive to aluminum, copper and other chemically active metals.

Waste Disposal

Incinerate in admixture with flammable solvent in furnace equipped with afterburner and scrubber.

3-Chlorophenol(108-43-0)Related Product Information

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