Tiron
Tiron Basic information
- Product Name:
- Tiron
- Synonyms:
-
- 1,3-Benzenedisulfonicacid,4,5-dihydroxy-,disodiumsalt
- 3,5-disulfocatecholdisodiumsalt
- 3-benzenedisulfonicacid,4,5-dihydroxy-disodiumsalt
- 4,5-dihydroxy-m-benzenedisulfonicacidisodiumsalt
- Disodium1,2-dihydroxybenzenedisulfonate
- Pyrocatechol-3,5-disodiumsulfonate
- sdd
- 4,5-DIHYDROXY-1,3-BENZENEDISULFONIC ACID, DISODIUM SALT MONOHYDRATE
- CAS:
- 149-45-1
- MF:
- C6H7NaO8S2
- MW:
- 294.22
- EINECS:
- 205-741-5
- Product Categories:
-
- Aromatic Phenols
- Mol File:
- 149-45-1.mol
Tiron Chemical Properties
- Melting point:
- 300 °C
- Density
- 2.064g/cm3 at 20℃
- bulk density
- 465kg/m3
- vapor pressure
- 0Pa at 25℃
- storage temp.
- Store at +15°C to +25°C.
- solubility
- 1350g/l
- form
- Powder
- color
- Off-white
- PH
- 5.0 (10g/l, H2O, 20℃)
- Water Solubility
- soluble
- Sensitive
- Hygroscopic
- λmax
- 290-291 nm (buffer pH 2.5)
- Merck
- 14,9465
- BRN
- 4629740
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- LogP
- 0.3 at 25℃ and pH6.5
- Surface tension
- 72.83mN/m at 1g/L and 19.5℃
- CAS DataBase Reference
- 149-45-1(CAS DataBase Reference)
- EPA Substance Registry System
- Disodium 4,5-dihydroxy-1,3-benzenedisulfonate (149-45-1)
MSDS
- Language:English Provider:Pyrocatechol-3,5-disulfonic acid disodium salt hydrate
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
Tiron Usage And Synthesis
Chemical Properties
light tan powder
Uses
Tiron is a superoxide scavenger used in the study and examination of oxide electronics. Maintains the ability to remove or destroy magnetic moments which may occur on the surface of such materials.
Uses
In determination of trace metals.
Definition
ChEBI: Tiron is an organic molecular entity.
in vivo
Tiron (200 mg/kg, oral gavage) ameliorates oxidative stress and inflammation in a murine model of airway remodeling[2].
Tiron (300 mg/kg, i.p., daily for two weeks) alleviated apoptosis of the left ventricular cardiomyocytes in STZ-induced diabetic mice[3].
| Animal Model: | BALB/c mice challenged with Ovalbumin (OVA) aerosol for 8 weeks[2] |
| Dosage: | 200 mg/kg |
| Administration: | Oral gavage. |
| Result: | Inhibited levels of NOx, IL-13 and TGF-β1, and immunoreactivity of NF-κB. |
| Animal Model: | STZ-induced diabetic mice[3] |
| Dosage: | 300 mg/kg |
| Administration: | i.p., daily for two weeks. |
| Result: | Reduced the levels of total oxidized proteins and advanced glycation end products (AGEs)-related proteins. Inhibited cardiac myocyte apoptosis. Decreased PKCδ localization on plasma membrane. |
Purification Methods
Recrystallise it from water [Hamaguchi et al. Anal Chim Acta 9 563 1962]. Itisan indicator colour reagent for Fe, Mn, Ti and Mo ions and complexes with Al, Cd, Co, Co, Fe (III), Mn, Pd, UO22+, VO2+ and Zn. [Beilstein 11 IV 630.]
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Tiron(149-45-1)Related Product Information
- NA
- Sodium Monofluorophosphate
- Sodium diphenylamine-4-sulfonate
- 4-tert-Butylcatechol
- Disodium succinate
- Chloral hydrate
- Ethylenediaminetetraacetic acid disodium salt
- Solvent Red 43
- Catechol
- Pyrocatechol Violet
- Dibutyl phthalate
- Sodium xylenesulfonate
- Phthalimide
- Diethyl phthalate
- Potassium phthalimide
- o-Phenylenediamine
- tert-Butylcatechol
- 1,3-BENZENEDISULFONIC ACID DISODIUM SALT