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DMT-2′O-TBDMS-rG(ib) Phosphoramidite

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DMT-2′O-TBDMS-rG(ib) Phosphoramidite Basic information

Product Name:
DMT-2′O-TBDMS-rG(ib) Phosphoramidite
Synonyms:
  • 2’-TBDMS-rG(N-ibu)Phosphoramidite
  • 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
  • 5'-O-DMT-2'-TBDMS-rG(N-iBu)-3'-CEDPA
  • (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(tert-butyldimethylsilyloxy)-5-(2-isobutyramido-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite
  • REF DUPL: 2'-TBDMS-rG(N-ibu)Phosphoramidite
  • i-bu-rG Phosphoramidite
  • DMT-2′O-TBDMS-rG(ib) Phosphoramidite
  • 2'-TBDMS-ibu-G-CE-Phosphoramidite
CAS:
147201-04-5
MF:
C50H68N7O9PSi
MW:
970.18
EINECS:
2017-001-1
Product Categories:
  • Pharmaceutical
  • Amidite
Mol File:
147201-04-5.mol
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DMT-2′O-TBDMS-rG(ib) Phosphoramidite Chemical Properties

storage temp. 
Sealed in dry,Store in freezer, under -20°C
form 
powder
pka
9.16±0.20(Predicted)
color 
white to off-white
InChI
InChI=1/C50H68N7O9PSi/c1-32(2)45(58)54-48-53-44-41(46(59)55-48)52-31-56(44)47-43(66-68(12,13)49(7,8)9)42(65-67(63-29-17-28-51)57(33(3)4)34(5)6)40(64-47)30-62-50(35-18-15-14-16-19-35,36-20-24-38(60-10)25-21-36)37-22-26-39(61-11)27-23-37/h14-16,18-27,31-34,40,42-43,47H,17,29-30H2,1-13H3,(H2,53,54,55,58,59)/t40-,42-,43-,47-,67?/s3
InChIKey
PGJKESPHANLWME-FTZVBZPOSA-N
SMILES
O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](O[Si](C(C)(C)C)(C)C)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,44,53,r|
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Safety Information

WGK Germany 
3
HS Code 
29349990
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DMT-2′O-TBDMS-rG(ib) Phosphoramidite Usage And Synthesis

Uses

5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is mainly used as a biochemical reagent.

Uses

DMT-2′O-TBDMS-rG(ib) Phosphoramidite was used to develop receptor-like approaches for high fidelity base paring at the 3’-terminus.

Definition

5'-O-DMT-2'-O-TBDMS-N2-Isobutyryl-Guanosine-CE Phosphoramidite (DMT-2′O-TBDMS-rG(ib) Phosphoramidite) is a TBDMS-protected nucleoside phosphoramidite that can be selected to help create special oligonucleotides.

DMT-2′O-TBDMS-rG(ib) PhosphoramiditeSupplier

Wuhu Huaren Science and Technology Co., Ltd. Gold
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0553-0553-0553-5842013-801-801 18155347026
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15555170917
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