Basic information Safety Supplier Related

Azido-PEG6-MS

Basic information Safety Supplier Related

Azido-PEG6-MS Basic information

Product Name:
Azido-PEG6-MS
Synonyms:
  • Azido-PEG6-MS
  • N3-PEG6-Ms
  • 17-Azido-3,6,9,12,15-pentaoxaheptadecyl methanesulfonate
CAS:
352439-38-4
MF:
C13H27N3O8S
MW:
385.43
Mol File:
352439-38-4.mol
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Azido-PEG6-MS Chemical Properties

form 
Liquid
color 
Colorless to light yellow
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Azido-PEG6-MS Usage And Synthesis

Uses

Azido-PEG6-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG6-MS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azido-PEG6-MSSupplier

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