Propargyl-PEG6-azide
Propargyl-PEG6-azide Basic information
- Product Name:
- Propargyl-PEG6-azide
- Synonyms:
-
- Propargyl-PEG6-azide
- Azido-PEG6-propargyl
- Propargyl-PEG6-N3
- 3,6,9,12,15,18-Hexaoxaheneicos-20-yne, 1-azido-
- CAS:
- 1198080-03-3
- MF:
- C15H27N3O6
- MW:
- 345.4
- Mol File:
- 1198080-03-3.mol
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Propargyl-PEG6-azide Usage And Synthesis
Biological Activity
Propargyl-PEG6-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Propargyl-PEG6-azideSupplier
Borenpharm Co., Ltd
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Zhengzhou Acme Chemical Co., Ltd.
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Amatek Scientific Co. Ltd.
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Xi'an Confluore Biological Technology Co., Ltd.
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- +86-156-80926068 +86-15680926068
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Wuhan Borenpharm Co., Ltd
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- 027-65563561 18717150066
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