Nicaraven
Nicaraven Basic information
- Product Name:
- Nicaraven
- Synonyms:
-
- n,n'-propylenedinicotinamide
- NICARAVEN
- 1,2-bis(nicotinamido)propane
- AVS
- N,N'-(1-Methylethylene)bis(pyridine-3-carboxamide)
- N,N'-(1-Methylethylene)bisnicotinamide
- N,N'-Propylenebis(nicotinamide)
- N,N'-Propylenebisnicotinamide
- CAS:
- 79455-30-4
- MF:
- C15H16N4O2
- MW:
- 284.31
- EINECS:
- 1806241-263-5
- Product Categories:
-
- Inhibitors
- Mol File:
- 79455-30-4.mol
More
Less
Nicaraven Chemical Properties
- Melting point:
- 156-157°
- Boiling point:
- 635.9±40.0 °C(Predicted)
- Density
- 1.213±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- DMF: 5 mg/ml; DMSO: 10 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): 2 mg/ml
- form
- A crystalline solid
- pka
- 12.93±0.46(Predicted)
- color
- White to off-white
More
Less
Nicaraven Usage And Synthesis
Description
Nicaraven is an antioxidant that exhibits hydroxyl radical scavenging activity in vitro. Nicaraven (1-3 mg/kg per min, i.v.) reduces occurrence of chronic cerebral vasospasms in a dose-dependent manner in a canine model of subarachnoid hemorrhage. In a canine model of warm hepatic ischemia and reperfusion injury, nicaraven (2 mg/kg per min, i.v.) reduces liver enzyme release and inhibits lipid peroxidation and neutrophil infiltration in the liver. Nicaraven (100 mg/kg per day, i.p.) also decreases plasma levels of the inflammatory cytokines Il-6 and Tnf-α and the urinary levels of 8-oxo-2''-deoxyguanosine, a marker of DNA oxidation, in a mouse model of radiation-induced injury.
NicaravenSupplier
Chembest Research Laboratories Limited
- Tel
- +86-21-20908456
- sales@BioChemBest.com
Hangzhou Yuhao Chemical Technology Co., Ltd
- Tel
- 0571-82693216
- info@yuhaochemical.com
Dalian Meilun Biotech Co., Ltd.
- Tel
- 0411-62910999 13889544652
- sales@meilune.com
Shanghai T&W Pharmaceutical Co., Ltd.
- Tel
- +86 21 61551611
HBCChem, Inc.
- Tel
- +1-510-219-6317
- sales@hbcchem.com
More
Less
Nicaraven(79455-30-4)Related Product Information
- Nicotinamide
- N-Isopropylacrylamide
- POLY(N-ISOPROPYL ACRYLAMIDE)
- POLYAMINOPROPYL BIGUANIDE
- Safinamide mesylate
- Dizocilpine
- Dapoxetine hydrochloride
- (R)-2-((R)-6,7-diMethoxy-1-(4-(trifluoroMethyl)phenethyl)-3,4-dihydroisoquinolin-2(1H)-yl)-N-Methyl-2-phenylacetaMide
- SB-705498
- Tideglusib
- Nicaraven dinitrate
- SG 1842
- Nicaraven