Mandipropamid Chemical Properties

Melting point:

96-97 °C

Boiling point:

608.6±55.0 °C(Predicted)

Density 

1.214±0.06 g/cm3(Predicted)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

Chloroform (Slightly), Dichloromethane (Slightly)

form 

powder

pka

13.90±0.46(Predicted)

color 

Pale Beige

LogP

4.160 (est)

EPA Substance Registry System

Benzeneacetamide, 4-chloro-N-[2-[3-methoxy-4-(2-propyn-1-yloxy)phenyl]ethyl]-.alpha.-(2-propyn-1-yloxy)- (374726-62-2)

Safety Information

WGK Germany 

3

Hazardous Substances Data

374726-62-2(Hazardous Substances Data)

Mandipropamid Usage And Synthesis

Chemical Properties

Dicynamid pure product is light yellow powder, melting point 96.4~97.3 ℃, vapor pressure <9.4×10-4mPa(25~50 ℃), distribution coefficient Kow lgP=3.2, Henry's coefficient <9.2×10-5 Pa-m3/mol(25 ℃, calculated value), density(22 ℃)1.24g/L. Solubility in water 4.2mg Solubility in water 4.2mg/L(25℃); Solubility in organic solvents (25℃, g/L): n-hexane 0.042, n-octanol 4.8, toluene 29, methanol 66, ethyl acetate 120, acetone 300, dichloromethane 400 Stable in pH=4~9.

Uses

Mandipropamid is a fungicide. It can be used on many fruit and vegetable crops, including potatoes, tomatoes, salad leaves and grapes. Manufactured by Syngenta.

Definition

ChEBI: 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide is a monocarboxylic acid amide resulting from the condensation of the carboxy group of p-chloromandelic acid propargyl ether with the amino group of 2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethylamine. It is a monocarboxylic acid amide, a terminal acetylenic compound, an aromatic ether and a member of monochlorobenzenes.

Biological Activity

Mandipropamid (Mandi) is an agrochemical extensively used as fungicide. Mandipropamid specifically induces complex formation between a sixfold mutant of the plant hormone receptor pyrabactin resistance 1 (PYR1) and abscisic acid insensitive (ABI). Mandipropamid is a highly cell permeable, low toxic chemical inducers of proximity in vivo. It induces rapid colocalization of proteins contained fused receptor domain PYRMandi and receiver domain ABI.

storage

Store at -20°C

Mandipropamid(374726-62-2)Related Product Information

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