3,4-Difluoroanisole Chemical Properties

Boiling point:

101.45°C (rough estimate)

Density 

1.216 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.469(lit.)

Flash point:

131 °F

storage temp. 

Sealed in dry,Room Temperature

form 

Liquid

color 

Clear colorless

Specific Gravity

1.216

BRN 

6717610

CAS DataBase Reference

115144-40-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,F,Xn

Risk Statements 

10-36/37/38

Safety Statements 

16-26-36-7/9

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

Hazard Note 

Flammable

HazardClass 

3

PackingGroup 

III

HS Code 

29093090

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3,4-Difluoroanisole Usage And Synthesis

Chemical Properties

CLEAR COLOURLESS LIQUID

Synthesis Reference(s)

[1] Method for preparing 3,4-difluoroanisole. CN105523904A

Synthesis

The method for preparing 3,4-difluoroanisole includes the steps that compound 3,4-difluorophenol is dissolved in acetonitrile, potassium carbonate is weighed, methyl iodide is dripped, and the mixture is reacted overnight at an indoor temperature; thin-1ayer chromatography is carried out on the next day, and it is discovered that the raw materials are completely reacted; reaction liquid is poured into water to be fully stirred, the lower layer organic phase is separated, then dichloromethane and water are added, and full washing and separation are carried out; afterwards, washing with water is conducted twice, and the organic phase is separated, dried and subjected to atmospheric distillation; the product, dichloromethane and residual acetonitrile are azeotropic, a vacuum pump is used for conducting reduced pressure distillation from the temperature of 60 DEG C, colorless clear liquid is steamed out when the temperature is raised to 120 DEG C, and accordingly the compound 3,4-difluoroanisole is obtained. 

3,4-Difluoroanisole(115144-40-6)Related Product Information

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