4-Ethoxybenzaldehyde Chemical Properties

Melting point:

13-14 °C(lit.)

Boiling point:

255 °C(lit.)

Density 

1.08 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.559(lit.)

FEMA 

2413 | P-ETHOXYBENZALDEHYDE

Flash point:

>230 °F

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

form 

Liquid

Specific Gravity

1.08

color 

Clear yellow to light brown

Odor

at 100.00 %. sweet spicy floral anisic

Odor Type

spicy

Water Solubility 

Insoluble in water.

Sensitive 

Air Sensitive

JECFA Number

879

BRN 

386863

LogP

2.23

CAS DataBase Reference

10031-82-0(CAS DataBase Reference)

NIST Chemistry Reference

Benzaldehyde, 4-ethoxy-(10031-82-0)

EPA Substance Registry System

Benzaldehyde, 4-ethoxy- (10031-82-0)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39-24/25-36

WGK Germany 

3

RTECS 

CU6100000

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29124990

MSDS

• Language:English Provider:4-Ethoxybenzaldehyde
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• Language:English Provider:ACROS
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4-Ethoxybenzaldehyde Usage And Synthesis

Description

4-Ethoxybenzaldehyde is a flavoring ingredient. 4-Ethoxybenzaldehyde can be used as an anti-inflammatory and prostaglandin E2 suppressor. It has also been indicated that it is useful in reducing facial erythema.

Chemical Properties

clear yellow to light brown liquid

Chemical Properties

p-Ethoxybenzaldehyde has a sweet, floral, and anise odor and a similar taste

Occurrence

Reported found in black tea

Uses

4-Ethoxybenzaldehyde was used as an anti-inflammatory and prostaglandin E2 suppressor in skin lightening agents.

Definition

ChEBI: 4-ethoxybenzaldehyde is an aromatic ether.

Preparation

By ethylation of p-hydroxybenzaldehyde using aluminum chloride catalyst.

Synthesis

p-Ethoxybenzaldehyde is synthesized by Ethylation of para-Hydroxybenzaldehyde. This aldehyde, which is very important as an intermediate in the manufacture of many naturally occurring flavor chemicals can be prepared from Phenol plus Hydrocyanic acid plus Hydrochloric acid.

References

Makino, Elizabeth T., et al. "Evaluation of a hydroquinone-free skin brightening product using in vitro inhibition of melanogenesis and clinical reduction of ultraviolet-induced hyperpigmentation." Journal of drugs in dermatology: JDD 12.3 (2013): s16-20.
Draelos, Zoe Diana, and Bryan B. Fuller. "Efficacy of 1% 4‐Ethoxybenzaldehyde in Reducing Facial Erythema." Dermatologic surgery31.s1 (2005): 881-886.
Cadby, P. "Estimating intakes of flavouring substances." (1996): 453-460.

4-Ethoxybenzaldehyde(10031-82-0)Related Product Information

• 2-Nitrobenzaldehyde
• 3,4,5-Trimethoxybenzaldehyde
• p-Tolualdehyde
• 4-tert-Butylbenzaldehyde
• DIETHOXYMETHANE
• 4-Ethylbenzaldehyde
• 2,5-Dimethoxybenzaldehyde
• 2,3,4-Trimethoxybenzaldehyde
• 4-Dimethylaminobenzaldehyde
• 3,5-Dimethoxybenzaldehyde
• Benzaldehyde
• 4-Hydroxybenzaldehyde
• 4-Ethoxyphenol
• p-Anisaldehyde
• 4-Formylbenzoic acid
• 4'-Ethoxyacetophenone
• Veratraldehyde
• Ethoxyquin