NEBULARINE
NEBULARINE Basic information
- Product Name:
- NEBULARINE
- Synonyms:
-
- 9-(beta-d-ribofuranosyl)purine
- 9-beta-d-ribofuranosyl-9h-purin
- 9-beta-d-ribofuranosyl-9h-purine
- 9-purineribonucleoside
- ribosyl-purin
- ribosylpurine
- 1-(9H-Purine-9-yl)-1-deoxy-β-D-ribofuranose
- 9-β-D-Ribofuranosyl-9H-purine
- CAS:
- 550-33-4
- MF:
- C10H12N4O4
- MW:
- 252.23
- EINECS:
- 208-981-9
- Product Categories:
-
- Sugars, Carbohydrates & Glucosides
- Bases & Related Reagents
- Nucleotides
- Mol File:
- 550-33-4.mol
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NEBULARINE Chemical Properties
- Melting point:
- 181-182°C
- alpha
- D25 -48.6° (H2O)
- Boiling point:
- 395.4°C (rough estimate)
- Density
- 1.3402 (rough estimate)
- refractive index
- 1.6500 (estimate)
- storage temp.
- 2-8°C
- solubility
- DMSO (Slightly), Ethanol, Methanol (Slightly)
- pka
- 13.13±0.70(Predicted)
- form
- Solid
- color
- Pale Beige to Beige
- Merck
- 13,6461
- Stability:
- Hygroscopic
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NEBULARINE Usage And Synthesis
Description
This purine base is produced by Agarius nebularis Batsch. (Syn. Clitocybe nebularis). It is laevorotatory with [α]25D - 48.6° (c 1.0, H20).
Chemical Properties
Crystalline Solid
Uses
Nebularine is shown to have inhibitory effects against mouse Sarcoma 180 and mycobacteria.
Definition
ChEBI: A purine ribonucleoside that is 9H-purine attached to a beta-D-ribofuranosyl residue at position 9 via a glycosidic (N-glycosyl) linkage.
storage
+4°C
Purification Methods
Nebularine is recrystallised from butanone/MeOH or EtOH and forms a MeOH photo-adduct. It is a strong inhibitor of adenosine deaminase [EC 3.5.4.4]. [Nair & Weichert Bioorg Chem 9 423 1980, Lfgren et al. Acta Chem Scand 7 225 1953, UV: Brown & Weliky J Biol Chem 204 1019 1953, Beilstein 26 III/IV 1740.]
NEBULARINESupplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
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- 821-50328103-801 18930552037
- 3bsc@sina.com
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
BOC Sciences
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
T&W GROUP
- Tel
- 021-61551611 13296011611
- contact@trustwe.com
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NEBULARINE(550-33-4)Related Product Information
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- 2',3'-O-Isopropylideneadenosine
- N6-BENZYLADENOSINE
- Bucladesine sodium
- Vidarabine
- Adenosine 5'-monophosphate monohydrate
- 2-Amino-6-chloropurine-9-riboside
- 8-BROMOADENOSINE
- 6-Chloropurine ribonucleoside
- N6-ISOPENTENYLADENOSINE-D6
- 2-Chloroadenosine
- ADENOSINE-2':3'-CYCLIC MONOPHOSPHATE, SODIUM SALT
- 6-THIOGUANOSINE
- 3'-ADENYLIC ACID
- 6-METHYLAMINOPURINE 9-RIBOFURANOSIDE
- S-(4-NITROBENZYL)-6-THIOINOSINE
- 6-MERCAPTOPURINE RIBOSIDE
- NBTGR