5-Indolylboronic acid Chemical Properties

Melting point:

170-175 °C

Boiling point:

433.2±37.0 °C(Predicted)

Density 

1.33±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

pka

8.91±0.30(Predicted)

form 

Crystalline Powder

color 

White

Sensitive 

Air Sensitive

CAS DataBase Reference

144104-59-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-21/22

Safety Statements 

26-36/37/39

WGK Germany 

3

Hazard Note 

Irritant/Keep Cold

HazardClass 

IRRITANT, KEEP COLD

HS Code 

29339900

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

5-Indolylboronic acid Usage And Synthesis

Chemical Properties

White to light yellow crystal powde

Uses

Indole-5-boronic acid is a useful reagent for palladium and copper catalyzed oxidative cross-coupling of mercaptoacetylenes and arylboronic acids. A reagent used in the synthesis of other biologically active molecules.

Uses

Reactant involved in the synthesis of biologically active molecules including:

• Indole inhibitors of MMP-13 for arthritic disease treatment
• Substituted pyrimidines acting as tubulin polymerization inhibitors

• Aryl- hetarylfurocoumarins
• Aryl-substituted oxabenzindoles and methanobenzindoles

• Oxidative cross-coupling with mercaptoacetylenes
• Trifluoromethylation

General Description

May contain varying amounts of anhydride

5-Indolylboronic acid(144104-59-6)Related Product Information

• Indole-3-butyric acid
• Indole-3-acetic acid
• Indometacin
• Folic acid
• 5-INDANOL
• Boric acid
• Citric acid
• Ethyl 2-(Chlorosulfonyl)acetate
• Indoline
• Indole-5-carboxaldehyde
• Indole-3-carboxaldehyde
• Indole-4-carboxaldehyde
• Methyl indole-5-carboxylate
• Methyl indole-4-carboxylate
• Indole-3-carboxylic acid
• Methyl indole-6-carboxylate
• Ethyl indole-2-carboxylate
• Ascoric Acid