Propargyl-PEG4-Maleimide
Propargyl-PEG4-Maleimide Basic information
- Product Name:
- Propargyl-PEG4-Maleimide
- Synonyms:
-
- Propargyl-PEG4-Maleimide
- Alkyne-PEG4-NH-Mal
- PROPARGYL-PEG4-AMIDO-MAL
- Alkyne-PEG4-Maleimide,Propargyl-PEG4-Maleimide
- 1H-Pyrrole-1-propanamide, 2,5-dihydro-2,5-dioxo-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl-
- 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(3,6,9,12-tetraoxapentadec-14-yn-1-yl)propanamide
- Propargyl-PEG4-amido-Maleimide
- Propargyl-PEG5-BMPA
- CAS:
- 1609651-90-2
- MF:
- C18H26N2O7
- MW:
- 382.41
- Product Categories:
-
- peg
- Mol File:
- 1609651-90-2.mol
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Propargyl-PEG4-Maleimide Chemical Properties
- storage temp.
- Storage temp. 2-8°C
- form
- Viscous Liquid
- color
- Colorless to light yellow
- Appearance
- Light yellow oil or waxy solid
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Propargyl-PEG4-Maleimide Usage And Synthesis
Uses
Alkyne-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Alkyne-PEG4-maleimide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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