ChemicalBook > CAS DataBase List > 1-Hydroxyibuprofen

1-Hydroxyibuprofen

Product Name
1-Hydroxyibuprofen
CAS No.
53949-53-4
Chemical Name
1-Hydroxyibuprofen
Synonyms
1-Hydroxyibuprofen;Ibuprofen EP Impurity L;Ibuprofen EP Impurity;Ibuprofen Impurity 12;Ibuprofen IMpurity-L(EP/BP);Arginine ibuprofen impurity L;2-[4-(1-Hydroxy-2-methylpropyl)phen;1-Hydroxy Ibuprofen (Ibuprofen Impurity L);Ibuprofen EP Impurity L：Ibuprofen Impurity L;Ibuprofen Impurity 12（Ibuprofen EP Impurity L）
CBNumber
CB01062052
Molecular Formula
C13H18O3
Formula Weight
222.28
MOL File
53949-53-4.mol
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1-Hydroxyibuprofen Property

Melting point:
80-85°C
Boiling point:
367.5±22.0 °C(Predicted)
Density 
1.119±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Acetonitrile (Slightly), Chloroform (Slightly, Heated), Methanol (Slightly)
pka
4.39±0.10(Predicted)
color 
White to Off-White
BRN 
22307543
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
62248
Product name
1-Hydroxyibuprofen
Purity
pharmaceutical impurity standard
Packaging
50mg
Price
$524
Updated
2024/03/01
Sigma-Aldrich
Product number
32496
Product name
1-Hydroxyibuprofen
Purity
VETRANAL
Packaging
10mg
Price
$467
Updated
2024/03/01
TRC
Product number
H942858
Product name
1-HydroxyIbuprofen(IbuprofenImpurityL)(MixtureofDiastereomers)
Packaging
5mg
Price
$140
Updated
2021/12/16
Biosynth Carbosynth
Product number
IH31798
Product name
1-Hydroxy-ibuprofen - Mixture of diastereoisomers
Packaging
1mg
Price
$160
Updated
2021/12/16
Biosynth Carbosynth
Product number
IH31798
Product name
1-Hydroxy-ibuprofen - Mixture of diastereoisomers
Packaging
2mg
Price
$250
Updated
2021/12/16
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1-Hydroxyibuprofen Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

1-Hydroxy Ibuprofen, also known as Ibuprofen EP Impurity L, is a degradation product of Ibuprofen. Ibuprofen is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and non-selective COX inhibitor.

Definition

ChEBI: 1-Hydroxyibuprofen is a monocarboxylic acid and a member of benzenes.

1-Hydroxyibuprofen Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Hydroxyibuprofen Suppliers

Canada 1 China 82 Europe 1 France 1 India 10 United Kingdom 1 United States 9 Global 105

53949-53-4, 1-HydroxyibuprofenRelated Search:

6-isobutyl-3-methyl-2,3-dihydro-1H-inden-1-one (2RS)-2-(4-BUTYLPHENYL)PROPANOIC ACID 4'-(2-Methylpropyl)acetophenone 3-(4-ISOBUTYL-PHENYL)-PROPIONIC ACID (2RS)-2-(4-FORMYLPHENYL)PROPANOIC ACID (2RS)-2-(4-ETHYLPHENYL)PROPANOIC ACID M-ISOBUTYL IBUPROFEN 1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE 4-(2-Methylpropyl)benzeneethanol trans-Ibuprofen IMpurity G rac a-Hydroxy Ibuprofen (S)-(+)-Ibuprofen Ibuprofen Ethyl Ester 2-[4-(2-Methylpropyl)phenyl] ethanol 2-(4-Methylphenyl)propanoic acid rac 2-Hydroxy Ibuprofen (R)-(-)-IBUPROFEN Ibuprofen EP Impurity I

  • 1-Hydroxy-ibuprofen - Mixture of diastereoisomers
  • Ibuprofen EP Impurity
  • 1-Hydroxy Ibuprofen (Ibuprofen Impurity L)(Mixture of Diastereomers)
  • 2-[4'-(1-Hydroxy-2-methylpropyl)phenyl]propionic Acid
  • 4-(1-Hydroxy-2-methylpropyl)-a-methylbenzeneacetic Acid
  • Benzeneacetic acid, 4-(1-hydroxy-2-methylpropyl)--alpha--methyl- (9CI)
  • 4-(1-Hydroxy-2-Methylpropyl)-α-Methylbenzeneacetic Acid
  • Ibuprofen IMpurity-L(EP/BP)
  • 1-Hydroxyibuprofen
  • 1-Hydroxy Ibuprofen (Ibuprofen Impurity L)
  • Ibuprofen EP Impurity L
  • Imp. L (EP): 2-[4-(1-Hydroxy-2-methylpropyl)phenyl]propanoic Acid(1-Hydroxyibuprofen)
  • Ibuprofen Impurity 12
  • Ibuprofen impurity 6/Ibuprofen EP Impurity L/1-Hydroxy Ibuprofen
  • Ibuprofen EP Impurity L：Ibuprofen Impurity L
  • 2-[4-(1-Hydroxy-2-methylpropyl)phen
  • Benzeneacetic acid, 4-(1-hydroxy-2-methylpropyl)-α-methyl-
  • Ibuprofen Impurity 12（Ibuprofen EP Impurity L）
  • 2-(4-(1-HYDROXY-2-METHYLPROPYL)-PHENYL)-PROPIONSAEURE
  • Arginine ibuprofen impurity L
  • 4-(1-hydroxy-2-methylpropyl)-alpha-methyl-Benzeneacetic acid
  • 53949-53-4
  • PHENYL
  • Aromatics
  • Impurities
  • Intermediates & Fine Chemicals
  • Pharmaceuticals