ChemicalBook > CAS DataBase List > 1-Hydroxyibuprofen

1-Hydroxyibuprofen

Product Name: 1-Hydroxyibuprofen
CAS No.: 53949-53-4
Chemical Name: 1-Hydroxyibuprofen
Synonyms: 1-Hydroxyibuprofen;Ibuprofen EP Impurity L;Ibuprofen EP Impurity;Ibuprofen Impurity 12;Ibuprofen IMpurity-L(EP/BP);C14278150 Ibuprofen-1-hydroxy;Arginine ibuprofen impurity L;2-[4-(1-Hydroxy-2-methylpropyl)phen;1-Hydroxyibuprofen 100 μg/ml Acetonitrile;1-Hydroxy Ibuprofen (Ibuprofen Impurity L)
CBNumber: CB01062052
Molecular Formula: C13H18O3
Formula Weight: 222.28
MOL File: 53949-53-4.mol

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1-Hydroxyibuprofen Property

Melting point:: 80-85°C
Boiling point:: 367.5±22.0 °C(Predicted)
Density: 1.119±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: Acetonitrile (Slightly), Chloroform (Slightly, Heated), Methanol (Slightly)
pka: 4.39±0.10(Predicted)
color: White to Off-White
BRN: 22307543
InChI: InChI=1S/C13H18O3/c1-8(2)12(14)11-6-4-10(5-7-11)9(3)13(15)16/h4-9,12,14H,1-3H3,(H,15,16)
InChIKey: RMOQYHYFRKTDRI-UHFFFAOYSA-N
SMILES: C1(C(C)C(O)=O)=CC=C(C(O)C(C)C)C=C1

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR3325
Product name: IBUPROFEN IMPURITY L
Purity: pharmaceutical secondary standard, certified reference material
Packaging: 50 mg
Price: $497
Updated: 2025/07/31

Sigma-Aldrich

Product number: 62248
Product name: 1-Hydroxyibuprofen
Purity: pharmaceutical impurity standard
Packaging: 50mg
Price: $539
Updated: 2025/07/31

Sigma-Aldrich

Product number: 32496
Product name: 1-Hydroxyibuprofen
Purity: VETRANAL
Packaging: 10mg
Price: $476
Updated: 2025/07/31

TRC

Product number: H942858
Product name: 1-HydroxyIbuprofen(IbuprofenImpurityL)(MixtureofDiastereomers)
Packaging: 5mg
Price: $140
Updated: 2021/12/16

Biosynth Carbosynth

Product number: IH31798
Product name: 1-Hydroxy-ibuprofen - Mixture of diastereoisomers
Packaging: 1mg
Price: $160
Updated: 2021/12/16

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1-Hydroxyibuprofen Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

1-Hydroxy Ibuprofen, also known as Ibuprofen EP Impurity L, is a degradation product of Ibuprofen. Ibuprofen is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and non-selective COX inhibitor.

Definition

ChEBI: 1-Hydroxyibuprofen is a monocarboxylic acid and a member of benzenes.

1-Hydroxyibuprofen Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Hydroxyibuprofen Suppliers

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53949-53-4, 1-HydroxyibuprofenRelated Search:

6-isobutyl-3-methyl-2,3-dihydro-1H-inden-1-one (2RS)-2-(4-BUTYLPHENYL)PROPANOIC ACID 4'-(2-Methylpropyl)acetophenone 3-(4-ISOBUTYL-PHENYL)-PROPIONIC ACID (2RS)-2-(4-FORMYLPHENYL)PROPANOIC ACID (2RS)-2-(4-ETHYLPHENYL)PROPANOIC ACID M-ISOBUTYL IBUPROFEN 1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE 4-(2-Methylpropyl)benzeneethanol trans-Ibuprofen IMpurity G rac a-Hydroxy Ibuprofen (S)-(+)-Ibuprofen Ibuprofen Ethyl Ester 2-[4-(2-Methylpropyl)phenyl] ethanol 2-(4-Methylphenyl)propanoic acid rac 2-Hydroxy Ibuprofen (R)-(-)-IBUPROFEN Ibuprofen EP Impurity I

1-Hydroxy-ibuprofen - Mixture of diastereoisomers

Ibuprofen EP Impurity

1-Hydroxy Ibuprofen (Ibuprofen Impurity L)(Mixture of Diastereomers)

2-[4'-(1-Hydroxy-2-methylpropyl)phenyl]propionic Acid

4-(1-Hydroxy-2-methylpropyl)-a-methylbenzeneacetic Acid

Benzeneacetic acid, 4-(1-hydroxy-2-methylpropyl)--alpha--methyl- (9CI)

4-(1-Hydroxy-2-Methylpropyl)-α-Methylbenzeneacetic Acid

Ibuprofen IMpurity-L(EP/BP)

1-Hydroxyibuprofen

1-Hydroxy Ibuprofen (Ibuprofen Impurity L)

Ibuprofen EP Impurity L

Imp. L (EP): 2-[4-(1-Hydroxy-2-methylpropyl)phenyl]propanoic Acid(1-Hydroxyibuprofen)

Ibuprofen Impurity 12

Ibuprofen impurity 6/Ibuprofen EP Impurity L/1-Hydroxy Ibuprofen

Ibuprofen EP Impurity L：Ibuprofen Impurity L

2-[4-(1-Hydroxy-2-methylpropyl)phen

Benzeneacetic acid, 4-(1-hydroxy-2-methylpropyl)-α-methyl-

Ibuprofen Impurity 12（Ibuprofen EP Impurity L）

2-(4-(1-HYDROXY-2-METHYLPROPYL)-PHENYL)-PROPIONSAEURE

4-(1-hydroxy-2-methylpropyl)-alpha-methyl-Benzeneacetic acid

1-Hydroxyibuprofen 100 μg/ml Acetonitrile

C14278150 Ibuprofen-1-hydroxy

Arginine ibuprofen impurity L

2-[4-(1-Hydroxy-2-methylpropyl)phenyl]propanoic Acid (1-Hydroxyibuprofen)

Ibuprofen Impurity L(Mixture of Diastereomers)

Ibuprofen Imp. L (EP): 2-4-(1-Hydroxy-2-methylpropyl) phenylpropanoic acid

53949-53-4

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