6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER

Product Name: 6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER
CAS No.: 885518-49-0
Chemical Name: 6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER
Synonyms: Methyl 6-bromo-(1H)-indaz...;6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER;6-BroMo-1H-indazol-4-carboxylic acid Methyl ester;6-BroMo-1H-indazole-4-carboxylic acid Methyl ester;1H-Indazole-4-carboxylic acid, 6-broMo-, Methyl ester;1H-Indazole-4-carboxylic acid, 6-bromo-, methyl ester (9CI, ACI)
CBNumber: CB0128102
Molecular Formula: C9H7BrN2O2
Formula Weight: 255.07
MOL File: Mol file

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6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER Property

Boiling point:: 395.9±22.0 °C(Predicted)
Density: 1.709±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 11.21±0.40(Predicted)
Appearance: light yellow solid
InChI: InChI=1S/C9H7BrN2O2/c1-14-9(13)6-2-5(10)3-8-7(6)4-11-12-8/h2-4H,1H3,(H,11,12)
InChIKey: FEPRHRPOKPTRQZ-UHFFFAOYSA-N
SMILES: N1C2=C(C(C(OC)=O)=CC(Br)=C2)C=N1

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Safety

Hazard Codes: Xn
Risk Statements: 22
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific

Product number: J91322
Product name: Methyl6-bromo-1H-indazole-4-carboxylate
Packaging: 1g
Price: $30
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H23-9-04
Product name: Methyl 6-bromo-1H-indazole-4-carboxylate
Purity: 98%
Packaging: 1g
Price: $45
Updated: 2021/12/16

ChemScene

Product number: CS-B0755
Product name: methyl6-bromo-1H-indazole-4-carboxylate
Packaging: 5g
Price: $62
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H23-9-04
Product name: Methyl 6-bromo-1H-indazole-4-carboxylate
Purity: 98%
Packaging: 5G
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: J91322
Product name: Methyl6-bromo-1H-indazole-4-carboxylate
Packaging: 5g
Price: $90
Updated: 2021/12/16

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6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production

Uses

Methyl 6-bromo-4-indazolecarboxylate is mainly used as an organic synthesis intermediate and is widely used in drug development and chemical research.

Synthesis

1346597-55-4

885518-49-0

Step 6: Synthesis of methyl 6-bromo-1H-indazole-4-carboxylate To a stirred solution of methyl 1-acetyl-6-bromo-1H-indazole-4-carboxylate (18 g, 61.0 mmol) in methanol (350 mL) was slowly added 6N HCl (350 mL). The reaction mixture was stirred at 60 °C for 8 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. Subsequently, the reaction mixture was alkalized with saturated NaHCO3 solution to pH 8. The precipitated solid was collected by filtration and dried under vacuum. The dried solid was stirred in ether for 15 min, filtered again and dried to give methyl 6-bromo-1H-indazole-4-carboxylate (11 g, 71.7% yield).

References

[1] Patent: WO2012/118812, 2012, A2. Location in patent: Page/Page column 313
[2] Patent: CN105037360, 2016, B. Location in patent: Paragraph 0400; 0401; 0402

6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER Suppliers

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View Lastest Price from 6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER manufacturers

Hebei Fengjia New Material Co., Ltd

Product: 6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER 885518-49-0
Price: US $5.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10000
Release date: 2024-08-08

Hebei Chuanghai Biotechnology Co., Ltd

Product: 6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER 885518-49-0
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-12-04

Shanghai Rlavie Technology Co ltd

Product: 6-BroMo-4-indazolecarboxylic acid Methyl ester 885518-49-0
Price: US $0.00-0.00/kg
Min. Order: 0.0001kg
Purity: 98%min
Supply Ability: 100kgs/month
Release date: 2022-05-10

885518-49-0, 6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTERRelated Search:

Formic acid VINYL CHLORIDE methyl6-chloropyridazine-4-carboxylate METHYL 6-CHLOROPYRIDAZINE-3-CARBOXYLATE 6-BROMO-1H-INDAZOLE-3-CARBALDEHYDE 6-BROMO-(1H)INDAZOLE-4-CARBOXYLIC ACID 2-Chloro-6-pyrazinecarboxylic acid methyl ester 6-METHYLPYRAZINE-2-CARBOXYLIC ACID METHYL ESTER Methyl 6-bromo-2-naphthoate 6-BROMOPYRIDINE-2-CARBOXYLIC ACID METHYL ESTER methyl 6-methylpyridine-2-carboxylate 6-CHLORO-2-PICOLINIC ACID METHYL ESTER Methyl 6-chloronicotinate Methyl 6-bromohexanoate Methyl 6-bromoisoquinoline-1-carboxylate methyl 6-chloropyrimidine-4-carboxylate METHYL 6-FORMYLNICOTINATE Methyl 6-bromonicotinate

6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER

6-BroMo-1H-indazol-4-carboxylic acid Methyl ester

Methyl 6-bromo-(1H)-indaz...

1H-Indazole-4-carboxylic acid, 6-broMo-, Methyl ester

6-BroMo-1H-indazole-4-carboxylic acid Methyl ester

1H-Indazole-4-carboxylic acid, 6-bromo-, methyl ester (9CI, ACI)

885518-49-0

Indazoles