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N-CHLOROSACCHARIN

Product Name
N-CHLOROSACCHARIN
CAS No.
14070-51-0
Chemical Name
N-CHLOROSACCHARIN
Synonyms
N-CHLOROSACCHARIN;N-Chlorosaccharin 99%;N-Chlorosaccharin,98%;N-Chlorosaccharin;2-CHLORO-1,2-BENZISOTHIAZOL-3(2H)ONE 1,1-DIOXIDE;2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide;1,2-Benzisothiazol-3(2H)-one, 2-chloro-, 1,1-dioxide
CBNumber
CB0141033
Molecular Formula
C7H4ClNO3S
Formula Weight
217.63
MOL File
14070-51-0.mol
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N-CHLOROSACCHARIN Property

Melting point:
148-152 °C (lit.)
Boiling point:
388.6±25.0 °C(Predicted)
Density 
1.77±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
soluble in Toluene
form 
powder to crystaline
pka
-24.37±0.20(Predicted)
color 
White to Almost white
InChI
InChI=1S/C7H4ClNO3S/c8-9-7(10)5-3-1-2-4-6(5)13(9,11)12/h1-4H
InChIKey
VKWMGUNWDFIWNW-UHFFFAOYSA-N
SMILES
S1(=O)(=O)C2=C(C=CC=C2)C(=O)N1Cl
CAS DataBase Reference
14070-51-0
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-40
Safety Statements 
22-26-36/37/39
WGK Germany 
3
HS Code 
29251100
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

H351Suspected of causing cancer

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
452742
Product name
N-Chlorosaccharin
Purity
99%
Packaging
25g
Price
$183
Updated
2023/01/07
TCI Chemical
Product number
C1674
Product name
N-Chlorosaccharin
Purity
>96.0%(T)
Packaging
5g
Price
$235
Updated
2025/07/31
TCI Chemical
Product number
C1674
Product name
N-Chlorosaccharin
Purity
>96.0%(T)
Packaging
25g
Price
$689
Updated
2025/07/31
TRC
Product number
C429128
Product name
2-Chlorobenzo[d]isothiazol-3(2H)-one-1,1-dioxide
Packaging
100mg
Price
$60
Updated
2021/12/16
AK Scientific
Product number
2137BB
Product name
N-Chlorosaccharin
Packaging
5g
Price
$131
Updated
2021/12/16
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N-CHLOROSACCHARIN Chemical Properties,Usage,Production

Chemical Properties

White to off-white crystalline powder

Synthesis

81-07-2

14070-51-0

1. Saccharin (6.0 g) was dissolved in methanol (120 mL), stirred at room temperature, tert-butyl hypochlorite (5 mL) was added slowly, and the reaction was carried out for 5 min to obtain N-chlorophthaloylbenzimide intermediate 1a (6.0 g, 84% yield). 2. Intermediate 1a (3.0 g) was mixed with silver trifluoromethylsulfide (3.6 g) in acetonitrile (40 mL), and the reaction was stirred at room temperature for 10 min to obtain the target product N-chlorophthaloylbenzimide 1 (3.3 g, 86% yield). Note: The product 1 is a white solid at room temperature, easily soluble in organic solvents such as dichloromethane, chloroform, acetone and acetonitrile.

References

[1] Synlett, 2006, # 2, p. 194 - 200
[2] Angewandte Chemie, International Edition, 2014, vol. 53, # 35, p. 9316 - 9320,5
[3] Angewandte Chemie, 2014, vol. 126, # 35, p. 9470 - 9474,5
[4] Patent: CN104945294, 2016, B. Location in patent: Paragraph 0135; 0136; 0137; 0138
[5] Patent: CN104945298, 2016, B. Location in patent: Paragraph 0187; 0188; 0189; 0190

N-CHLOROSACCHARIN Preparation Products And Raw materials

Raw materials

Preparation Products

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14070-51-0, N-CHLOROSACCHARINRelated Search:

Sodium N-cyclohexylsulfamate HOAt N-Hydroxyethylphthalimide N-Hydroxyphthalimide N-(Hydroxymethyl)phthalimide Sucralose Potassium sorbate FOOD ADDITIVES Sodium nitrite 2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE 1,2-Benzisothiazol-3(2H)-one N-CHLOROSACCHARIN Saccharin

  • 2-CHLORO-1,2-BENZISOTHIAZOL-3(2H)ONE 1,1-DIOXIDE
  • N-Chlorosaccharin,98%
  • N-CHLOROSACCHARIN
  • N-Chlorosaccharin 99%
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  • 2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide
  • <i>N</i>-Chlorosaccharin
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