5-Chloro-2-nitroaniline

Description Preparation

Product Name: 5-Chloro-2-nitroaniline
CAS No.: 1635-61-6
Chemical Name: 5-Chloro-2-nitroaniline
Synonyms: 5-CHLORO-2-NITROBENZENAMINE;oro-2-nitroaniL;TIMTEC-BB SBB003828;5-Chlor-2-nitroanilin;5-CHLORO-2-NITROANILINE;2-NITRO-5-CHLOROANILINE;5-Chloro-2-nitroamiline;Atorvastatin Impurity 146;Aniline, 5-chloro-2-nitro-;5-Chloro-2-nitrophenylamine
CBNumber: CB0141336
Molecular Formula: C6H5ClN2O2
Formula Weight: 172.57
MOL File: 1635-61-6.mol

More

Less

5-Chloro-2-nitroaniline Property

Melting point:: 125-129 °C (dec.)(lit.)
Boiling point:: 200°C (rough estimate)
Density: 1.5610 (rough estimate)
refractive index: 1.5870 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: soluble in Chloroform, Methanol
form: Liquid
pka: -1.46±0.25(Predicted)
color: Clear colorless to light yellow
BRN: 2210201
InChIKey: ZCWXYZBQDNFULS-UHFFFAOYSA-N
CAS DataBase Reference: 1635-61-6(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: T+,N,T
Risk Statements: 26/27/28-33-51/53
Safety Statements: 28-36/37-45-61-28A
RIDADR: UN 2237 6.1/PG 3
WGK Germany: 3
F: 9-23
Hazard Note: Irritant
HazardClass: 6.1
PackingGroup: III
HS Code: 29214210

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P262Do not get in eyes, on skin, or on clothing.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 269050
Product name: 5-Chloro-2-nitroaniline
Purity: 97%
Packaging: 25g
Price: $93.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: 269050
Product name: 5-Chloro-2-nitroaniline
Purity: 97%
Packaging: 5g
Price: $55.6
Updated: 2023/06/20

TCI Chemical

Product number: C1139
Product name: 5-Chloro-2-nitroaniline
Purity: >99.0%(GC)
Packaging: 25g
Price: $49
Updated: 2024/03/01

TCI Chemical

Product number: C1139
Product name: 5-Chloro-2-nitroaniline
Purity: >99.0%(GC)
Packaging: 250g
Price: $236
Updated: 2024/03/01

Alfa Aesar

Product number: A11241
Product name: 5-Chloro-2-nitroaniline, 97%
Packaging: 25g
Price: $84.65
Updated: 2024/03/01

More

Less

5-Chloro-2-nitroaniline Chemical Properties,Usage,Production

Description

2-Nitro-5-chloroaniline is an important pharmaceutical and veterinary drug intermediate. It has been applied in the upgraded product of veterinary drug albendazole-fenbendazole, and has a broad market prospect.

Preparation

Add 2.46mol of 2,4-dichloronitrobenzene, 7.72mol of toluene to a 3L autoclave, seal the autoclave, replace the air with nitrogen, then pass in 14.1mol of liquid ammonia, increase the temperature to 160℃, continue the reaction for 8h, and then lower the temperature to 40℃, drain the excess ammonia gas, open the kettle, add the obtained solid-liquid mixture to 800mL of water, continue to cool to 10℃, filter, add the resulting filter cake to the water, continue beating and filtering, the obtained solid is crystallized with methanol to obtain 388g , yield 91.2%, the purity of the liquid phase external standard is 99.5%.

Chemical Properties

yellow to orange powder

Uses

5-Chloro-2-nitroaniline is a useful synthetic intermediate. It can be used as a reagent to synthesize benzamide derivatives as histone deacetylase inhibitors. It is an intermediate used to synthesize 1-Nitro Febantel a Febantel impurity.

Uses

5-Chloro-2-nitroaniline was used in the synthesis of 5-(4-substituted piperazin-1-yl)-2-nitroanilines and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates.

Application

5-Chloro-2-nitroaniline was used in the synthesis of 5-(4-substituted piperazin-1-yl)-2-nitroanilines and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates.
The coupling of divinylbenzene cross-linked polystyrene with 5-chloro-2-nitroaniline followed by oxidative decyanation afforded benzophenone.

General Description

The coupling of divinylbenzene cross-linked polystyrene with 5-chloro-2-nitroaniline followed by oxidative decyanation afforded benzophenone.

5-Chloro-2-nitroaniline Preparation Products And Raw materials

Raw materials

Preparation Products

4-FLUORO-2-NITROBENZONITRILE 6-CHLORO-2,3-DIOXO-1,2,3,4-TETRAHYDROQUINOXALINE 4-Chloro-o-phenylenediamine 2,3,6-TRICHLOROQUINOXALINE 6-CHLOROQUINOXALINE Fenbendazole

More

Less

5-Chloro-2-nitroaniline Suppliers

Americas 1 Belgium 2 Canada 2 China 263 Europe 2 Germany 4 India 14 Japan 3 Slovakia 1 Switzerland 1 Ukraine 2 United Kingdom 9 United States 32 Global 336

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

HBCChem, Inc.

Tel: +1-510-219-6317
Fax: +1-650-486-1361
Email: sales@hbcchem.com
Country: United States
ProdList: 10648
Advantage: 60

AbaChemScene

Tel: 732-484-9848
Fax: 888-484-5008
Email: sales@chemscene.com
Country: United States
ProdList: 3982
Advantage: 60

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Aceschem Inc.

Tel: +1-817863-6948 +1-（817）863-6948
Email: sales@aceschem.com
Country: United States
ProdList: 19632
Advantage: 58

Synthonix Inc

Tel: --
Fax: --
Email: info@synthonix.com
Country: United States
ProdList: 6872
Advantage: 58

SynQuest Laboratories, Inc.

Tel: --
Fax: --
Email: info@synquestlabs.com
Country: United States
ProdList: 6871
Advantage: 62

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

TCI America

Tel: --
Fax: --
Email: sales@tciamerica.com
Country: United States
ProdList: 6909
Advantage: 75

Frontier Scientific, Inc.

Tel: --
Fax: --
Email: sales@frontiersci.com
Country: United States
ProdList: 6222
Advantage: 86

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

HBCChem Inc.

Tel: --
Fax: --
Email: sales@hbcchem-inc.com
Country: United States
ProdList: 4569
Advantage: 30

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6962
Advantage: 56

AlliChem, LLC

Tel: --
Fax: --
Email: sales@allichemllc.com
Country: United States
ProdList: 6516
Advantage: 60

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

Parish Chemical Company

Tel: --
Fax: --
Country: United States
ProdList: 1248
Advantage: 47

Ryan Scientific, Inc.

Tel: --
Fax: --
Email: ryan.reichlyn@ryansci.com
Country: United States
ProdList: 6439
Advantage: 60

AstaTech, Inc

Tel: --
Fax: --
Email: sales@astatechinc.com
Country: United States
ProdList: 6371
Advantage: 58

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

2A PharmaChem USA

Tel: --
Fax: --
Email: sales@2apharmachem.com
Country: United States
ProdList: 6137
Advantage: 39

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

HONEST JOY HOLDINGS LIMITED

Tel: --
Fax: --
Email: sales@honestjoy.cn
Country: United States
ProdList: 6675
Advantage: 54

Ivy Fine Chemicals

Tel: --
Fax: --
Email: sales@ivychem.com
Country: United States
ProdList: 6493
Advantage: 58

TimTec Corporation

Tel: --
Fax: --
Email: info@timtec.net
Country: United States
ProdList: 6891
Advantage: 68

ChemPacific Corporation

Tel: --
Fax: --
Email: sales@chempacific.com
Country: United States
ProdList: 6891
Advantage: 51

Alfa Aesar

Tel: --
Fax: --
Email: tech@alfa.com
Country: United States
ProdList: 6814
Advantage: 81

BOSCHE SCIENTIFIC, LLC

Tel: --
Fax: --
Email: Sales@BoscheSci.com
Country: United States
ProdList: 6477
Advantage: 55

Beta Pharma, Inc.

Tel: --
Fax: --
Email: sales@betapharma.com
Country: United States
ProdList: 6226
Advantage: 60

ASDI Incorporated

Tel: --
Fax: --
Email: customerservice@asdi.net
Country: United States
ProdList: 6922
Advantage: 67

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

AB Chem Technologies, LLC

Tel: --
Fax: --
Email: sales@abchemtech.com
Country: United States
ProdList: 1101
Advantage: 46

More

Less

View Lastest Price from 5-Chloro-2-nitroaniline manufacturers

Nanjing Fred Technology Co., Ltd

Product: 5-Chloro-2-nitroaniline 1635-61-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1 ton
Release date: 2023-12-28

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 5-Chloro-2-nitroaniline 1635-61-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-24

Hebei Chuanghai Biotechnology Co,.LTD

Product: 5-Chloro-2-nitroaniline 1635-61-6
Price: US $9.00/KG
Min. Order: 1KG
Purity: 99.8%
Supply Ability: 100tons
Release date: 2024-08-23

1635-61-6, 5-Chloro-2-nitroanilineRelated Search:

2-Nitroaniline 4-Chlorobenzenamine hydrochloride 3,4-Dichloroaniline 3,5-Dichloroaniline 4-Chloroaniline 5-Chloro-2-methylaniline 2-Chloroaniline 4-Nitroaniline 4-CHLORO-2-NITROANILINE 3-Chloroaniline 2,5-Dichloroaniline N-Methyl-4-nitroaniline DICHLORPHENAMIDE BULK POWDER 5-CHLORO-2-NITRODIPHENYLAMINE N1-(5-CHLORO-4-FLUORO-2-NITROPHENYL)ACETAMIDE N1-(4,5-DICHLORO-2-NITROPHENYL)ACETAMIDE 5-CHLORO-4-METHYL-2-NITROANILINE 3-CHLORO-2-NITROANILINE

TIMTEC-BB SBB003828

2-AMINO-4-CHLORO-NITROBENZENE

5-CHLORO-2-NITROANILINE

5-CHLORO-2-NITROBENZENAMINE

5-chloro-2-nitro-benzenamin

Benzenamine, 5-chloro-2-nitro-

2-NITRO-5-CHLOROANILINE

2-Amino-4-chloro-1-nitrobenzene

5-Chloro-2-nitrophenylamine

5-Chloro-2-nitroaniline ,98%

5-Chloro-2-nitroaniline,97%

5-Chloro-2-nitroaniline, 97% 50GR

5-Chloro-2-nitroaniline, 97% 5GR

5-Chlor-2-nitroanilin

5-CHLORO-2-NITROANILINE 99+%

5-Chloro-2-nitroamiline

5-CHLORO-2-NITROANILINE FOR SYNTHESIS

5-Chloro-2-nitroaniline 97%

Aniline, 5-chloro-2-nitro-

oro-2-nitroaniL

5-Chloro-2-nitroaniline &gt

5-Chloro-2-nitroaniline ISO 9001：2015 REACH

Atorvastatin Impurity 146

1635-61-6

AMINE

Building Blocks

Amines

C2 to C6

Organic Building Blocks

Nitrogen Compounds

Pyrimidines

API intermediates