ChemicalBook > CAS DataBase List > 5-Nitro-2-furoic acid

5-Nitro-2-furoic acid

Product Name: 5-Nitro-2-furoic acid
CAS No.: 645-12-5
Chemical Name: 5-Nitro-2-furoic acid
Synonyms: Nitrofurate;5-nitrofuroicacid;5-nitropyromucate;5-Nitrofuroic acid;RARECHEM AL BO 1619;5-nitro-2-furoicaci;5-NITRO-2-FUROIC ACID;5-Nitropyromucic acid;2-CARBOXY-5-NITROFURAN;2-Furoic acid, 5-nitro-
CBNumber: CB0150392
Molecular Formula: C5H3NO5
Formula Weight: 157.08
MOL File: 645-12-5.mol

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5-Nitro-2-furoic acid Property

Melting point:: 185-189 °C (lit.)
Boiling point:: 281.7°C (rough estimate)
Density: 1.8109 (rough estimate)
refractive index: 1.4798 (estimate)
storage temp.: Sealed in dry,2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 2.06±0.10(Predicted)
color: White to Light Yellow
Water Solubility: Slightly soluble in water.
BRN: 139373
InChI: InChI=1S/C5H3NO5/c7-5(8)3-1-2-4(11-3)6(9)10/h1-2H,(H,7,8)
InChIKey: IODMEDPPCXSFLD-UHFFFAOYSA-N
SMILES: O1C([N+]([O-])=O)=CC=C1C(O)=O
CAS DataBase Reference: 645-12-5(CAS DataBase Reference)
NIST Chemistry Reference: 5-Nitrofuran-2-carboxylic acid(645-12-5)

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Safety

Hazard Codes: Xn
Risk Statements: 68-36/37/38-40
Safety Statements: 37/39-36/37-36-22
WGK Germany: 3
RTECS: LV2012000
HS Code: 2932.19.5100

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H319Causes serious eye irritation

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 155713
Product name: 5-Nitro-2-furoic acid
Purity: 98%
Packaging: 5g
Price: $130
Updated: 2025/07/31

TCI Chemical

Product number: N0557
Product name: 5-Nitro-2-furancarboxylic Acid
Purity: >98.0%(T)
Packaging: 5g
Price: $48
Updated: 2025/07/31

TRC

Product number: N495955
Product name: Nitrofurate
Packaging: 1g
Price: $65
Updated: 2021/12/16

TRC

Product number: N495955
Product name: Nitrofurate
Packaging: 250mg
Price: $50
Updated: 2021/12/16

Chem-Impex

Product number: 42882
Product name: 5-Nitro-2-furancarboxylicacid,≥98%(GC)
Purity: ≥98%(GC)
Packaging: 5G
Price: $58.94
Updated: 2021/12/16

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5-Nitro-2-furoic acid Chemical Properties,Usage,Production

Chemical Properties

yellow crystalline powder

Uses

5-Nitro-2-furoic acid is a representative of 2-substituted 5-nitrofurans. A number of nitrofurans have been used as antibacterial, antiprotozoal, and anthelmintic drugs in humans and animals. 2-Substituted 5-nitrofurans have been used worldwide as human and veterinary medicines, food preservatives, and feed additives, and they are utilized in human medicine as antibacterial agents. Therefore, the relationship between the antibacterial effect and the mutagenicity of these compounds and their oxidized metabolites is important. Comparison of the antibacterial effects and genotoxic potencies of nitrofuran drugs and their oxidative metabolites may provide a new direction for selecting nitrofuran drugs for human use.

Uses

5-Nitro-2-furoic acid was used in the preparation of [1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b][1,3,4] thiadiazoles. The FT-IR and FT-Raman spectra of 5-Nitro-2-furoic acid has also been studied.

General Description

The FT-IR and FT-Raman spectra of 5-Nitro-2-furoic acid has been studied.

Environmental Fate

5-Nitro^-2-furoic acid is a yellow crystalline powder with molecular weight of 157.08 g mol^-1 and density of 1.72 g cm^-3. The boiling point is 332.4 ℃ and the melting point is 185.00– 189.00 ℃ at 760 mm Hg. Vapor pressure is 5.83E-05 mm Hg at 25 ℃ and enthalpy of vaporization is 60.71 kJ mol^-1. 5-Nitro^-2-furoic acid is very soluble in water. It is stable under normal temperature and pressure.

Toxicity evaluation

The toxicological properties of this compound have not been fully investigated. However, as a minimum precaution, it should be considered harmful. Precautions should be taken and procedures adopted to prevent exposure.

5-Nitro-2-furoic acid Preparation Products And Raw materials

Raw materials

SODIUM DICHROMATE p-Toluenesulfonic acid Acetic anhydride Sodium sulfate Diethyl ether Ethyl acetate Sodium bicarbonate Nitric acid Sodium hydroxide Pyridine Furfural PETROLEUM ETHER Sulfuric acid

Preparation Products

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View Lastest Price from 5-Nitro-2-furoic acid manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-Nitro-2-furoic acid 645-12-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-Nitro-2-furancarboxylic Acid 645-12-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

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5-nitrofuran-2-carboxylic acid - [N87154]

645-12-5

O2NC4H2OCOOH

C5H3NO5

CARBOXYLIC ACID

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