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5-Nitro-2-furoic acid

Product Name
5-Nitro-2-furoic acid
CAS No.
645-12-5
Chemical Name
5-Nitro-2-furoic acid
Synonyms
Nitrofurate;5-nitrofuroicacid;5-nitropyromucate;5-Nitrofuroic acid;RARECHEM AL BO 1619;5-nitro-2-furoicaci;5-NITRO-2-FUROIC ACID;5-Nitropyromucic acid;2-CARBOXY-5-NITROFURAN;2-Furoic acid, 5-nitro-
CBNumber
CB0150392
Molecular Formula
C5H3NO5
Formula Weight
157.08
MOL File
645-12-5.mol
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5-Nitro-2-furoic acid Property

Melting point:
185-189 °C (lit.)
Boiling point:
281.7°C (rough estimate)
Density 
1.8109 (rough estimate)
refractive index 
1.4798 (estimate)
storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
2.06±0.10(Predicted)
color 
White to Light Yellow
Water Solubility 
Slightly soluble in water.
BRN 
139373
CAS DataBase Reference
645-12-5(CAS DataBase Reference)
NIST Chemistry Reference
5-Nitrofuran-2-carboxylic acid(645-12-5)
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Safety

Hazard Codes 
Xn
Risk Statements 
68-36/37/38-40
Safety Statements 
37/39-36/37-36-22
WGK Germany 
3
RTECS 
LV2012000
HS Code 
2932.19.5100
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
155713
Product name
5-Nitro-2-furoic acid
Purity
98%
Packaging
5g
Price
$126
Updated
2024/03/01
TCI Chemical
Product number
N0557
Product name
5-Nitro-2-furancarboxylic Acid
Purity
>98.0%(T)
Packaging
5g
Price
$48
Updated
2024/03/01
Alfa Aesar
Product number
A10597
Product name
5-Nitro-2-furoic acid, 98+%
Packaging
5g
Price
$31.65
Updated
2024/03/01
Alfa Aesar
Product number
A10597
Product name
5-Nitro-2-furoic acid, 98+%
Packaging
25g
Price
$117.65
Updated
2024/03/01
Alfa Aesar
Product number
A10597
Product name
5-Nitro-2-furoic acid, 98+%
Packaging
100g
Price
$378.65
Updated
2024/03/01
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5-Nitro-2-furoic acid Chemical Properties,Usage,Production

Chemical Properties

yellow crystalline powder

Uses

5-Nitro-2-furoic acid is a representative of 2-substituted 5-nitrofurans. A number of nitrofurans have been used as antibacterial, antiprotozoal, and anthelmintic drugs in humans and animals. 2-Substituted 5-nitrofurans have been used worldwide as human and veterinary medicines, food preservatives, and feed additives, and they are utilized in human medicine as antibacterial agents. Therefore, the relationship between the antibacterial effect and the mutagenicity of these compounds and their oxidized metabolites is important. Comparison of the antibacterial effects and genotoxic potencies of nitrofuran drugs and their oxidative metabolites may provide a new direction for selecting nitrofuran drugs for human use.

Uses

5-Nitro-2-furoic acid was used in the preparation of [1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b][1,3,4] thiadiazoles. The FT-IR and FT-Raman spectra of 5-Nitro-2-furoic acid has also been studied.

General Description

The FT-IR and FT-Raman spectra of 5-Nitro-2-furoic acid has been studied.

Environmental Fate

5-Nitro-2-furoic acid is a yellow crystalline powder with molecular weight of 157.08 g mol-1 and density of 1.72 g cm-3. The boiling point is 332.4 ℃ and the melting point is 185.00– 189.00 ℃ at 760 mm Hg. Vapor pressure is 5.83E-05 mm Hg at 25 ℃ and enthalpy of vaporization is 60.71 kJ mol-1. 5-Nitro-2-furoic acid is very soluble in water. It is stable under normal temperature and pressure.

Toxicity evaluation

The toxicological properties of this compound have not been fully investigated. However, as a minimum precaution, it should be considered harmful. Precautions should be taken and procedures adopted to prevent exposure.

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5-Nitro-2-furoic acid Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
Kanto Chemical Co., Inc.
Tel
--
Fax
--
Email
reag-info@gms.kanto.co.jp
Country
Japan
ProdList
6756
Advantage
74
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View Lastest Price from 5-Nitro-2-furoic acid manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
5-Nitro-2-furoic acid 645-12-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-Nitro-2-furancarboxylic Acid 645-12-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

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