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Methyl thioglycolate

Product Name
Methyl thioglycolate
CAS No.
2365-48-2
Chemical Name
Methyl thioglycolate
Synonyms
Methyl 2-mercaptoacetate;MTG;METHYL MERCAPTOACETATE;THIOGLYCOLIC ACID METHYL ESTER;MERCAPTOACETIC ACID METHYL ESTER;METG;usafek-7119;USAF ek-7119;Articaine-003;Methy Diglycolate
CBNumber
CB0165491
Molecular Formula
C3H6O2S
Formula Weight
106.14
MOL File
2365-48-2.mol
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Methyl thioglycolate Property

Melting point:
-24 °C
Boiling point:
42-43 °C/10 mmHg (lit.)
Density 
1.187 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.466(lit.)
Flash point:
86 °F
storage temp. 
Store below +30°C.
solubility 
40g/l
form 
Liquid
pka
8.04±0.10(Predicted)
color 
Clear colorless
Water Solubility 
40 g/L (20 ºC)
Sensitive 
Air Sensitive
BRN 
506259
InChIKey
MKIJJIMOAABWGF-UHFFFAOYSA-N
CAS DataBase Reference
2365-48-2(CAS DataBase Reference)
NIST Chemistry Reference
Acetic acid, mercapto-, methyl ester(2365-48-2)
EPA Substance Registry System
Acetic acid, mercapto-, methyl ester (2365-48-2)
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Safety

Hazard Codes 
Xn,T
Risk Statements 
10-20/22-36/37/38-25
Safety Statements 
26-36/37-45-36/37/39-28A
RIDADR 
UN 1992 3/PG 3
WGK Germany 
1
RTECS 
AI7350000
TSCA 
Yes
HazardClass 
3
PackingGroup 
III
HS Code 
29309070
Hazardous Substances Data
2365-48-2(Hazardous Substances Data)
Toxicity
mouse,LD50,intraperitoneal,100mg/kg (100mg/kg),National Technical Information Service. Vol. AD277-689,
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
108995
Product name
Methyl thioglycolate
Purity
95%
Packaging
5g
Price
$36.4
Updated
2024/03/01
Sigma-Aldrich
Product number
108995
Product name
Methyl thioglycolate
Purity
95%
Packaging
100g
Price
$43.2
Updated
2024/03/01
TCI Chemical
Product number
T1287
Product name
Methyl Thioglycolate
Purity
>98.0%(GC)
Packaging
25g
Price
$25
Updated
2024/03/01
TCI Chemical
Product number
T1287
Product name
Methyl Thioglycolate
Purity
>98.0%(GC)
Packaging
100g
Price
$49
Updated
2024/03/01
Alfa Aesar
Product number
L03783
Product name
Methyl mercaptoacetate, 98%
Packaging
100g
Price
$29.65
Updated
2024/03/01
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Methyl thioglycolate Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLOURLESS LIQUID

Uses

Methyl thioglycolate was used in the preparation of 3-carbomethoxy-4- oxotetrahydrothiopyran, 2- and 4-carbomethoxy-3-oxotetrahydrothiophene. It is used to prepare methyl thioglycolate and aminoethanethiol conjugated gold nanorods.

Uses

Methyl Thioglycolate is an derivative of Thioglycolic Acid (T350760), an organic compound containing both a thiol and a carboxylic acid functional groups. Thioglycolic Acid and its derivatives are oft en used in organic synthesis as a nucleophile in thioglycolysis reactions and is also used as a S transfer agent for sulfonyl chloride synthesis. Methyl Thioglycolate have been studied for the its inf luence on neocarzinostatin activation and expression of DNA damage.

Application

Methyl thioglycolate is a chemical compound that is used in the pharmaceutical industry as an intermediate. It has been used to synthesize anti-inflammatory drugs, such as aspirin and ibuprofen, and also for the treatment of autoimmune diseases. Methyl thioglycolate binds to amino acids on the surface of bacteria, which prevents them from functioning properly. This binding causes the cells to stop growing and die.

Definition

Methyl thioglycolate are widely used in free-radical photoinitiated polymerization reactions. In particular, the use of methyl thioglycolate (MTG), CH3OC(O)CH2SH, results in greater photopolymerization reaction rates, attributed to a weakening of the sulfur–hydrogen bond by hydrogen bonding of the thiol group. MTG constitutes the smaller exponent of the series of CH3OC(O)(CH2)nSH compounds, reported as intermediated in the organic sulfur cycle in marine environments, produced by marine phytoplankton.

General Description

Methyl thioglycolate reacts with nonprotein component of the antitumor antibiotic neocarzinostatin to form 1:1 adduct. It reacts with isothiocyanate to form Rhodanine.

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View Lastest Price from Methyl thioglycolate manufacturers

Henan Fengda Chemical Co., Ltd
Product
Methyl thioglycolate 2365-48-2
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-24
Wuhan Boyuan Import & Export Co., LTD
Product
Methyl Thioglycolate
Price
US $20.00-15.00/kg
Min. Order
1kg
Purity
99.50%
Supply Ability
30tons
Release date
2023-06-19
Hebei Yanxi Chemical Co., Ltd.
Product
methyl 2-sulfanylacetate 2365-48-2
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-10-12

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