COLISTIN

Neurotoxicity and Nephrotoxicity

Product Name: COLISTIN
CAS No.: 1066-17-7
Chemical Name: COLISTIN
Synonyms: COLISTIN;kangdisu;totazina;colimycin;colomycin;Aids033059;coly-mycin;colymysins;kolimitsin;Aids-033059
CBNumber: CB0169873
Molecular Formula: C52H98N16O13
Formula Weight: 1155.43
MOL File: 1066-17-7.mol

More

Less

COLISTIN Property

Boiling point:: 807.67°C (rough estimate)
Density: 1.1050 (rough estimate)
refractive index: 1.6700 (estimate)
storage temp.: Store at -20°C
solubility: PBS (pH 7.2): 10 mg/ml
CAS DataBase Reference: 1066-17-7

More

Less

Safety

RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III
Hazardous Substances Data: 1066-17-7(Hazardous Substances Data)
Toxicity: cat,LDLo,subcutaneous,250mg/kg (250mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGBEHAVIORAL: ATAXIABEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY),Antibiotiki. Vol. 5(4), Pg. 10, 1960.

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0001999
Product name: Colistin for system suitability
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0001999
Price: $152
Updated: 2024/03/01

Cayman Chemical

Product number: 23487
Product name: Colistin
Purity: ≥95%
Packaging: 100mg
Price: $285
Updated: 2021/12/16

Cayman Chemical

Product number: 23487
Product name: Colistin
Purity: ≥95%
Packaging: 25mg
Price: $89
Updated: 2021/12/16

AK Scientific

Product number: 9632AJ
Product name: Colistin
Packaging: 100mg
Price: $484
Updated: 2021/12/16

AK Scientific

Product number: 9632AJ
Product name: Colistin
Packaging: 25mg
Price: $220
Updated: 2021/12/16

More

Less

COLISTIN Chemical Properties,Usage,Production

Neurotoxicity and Nephrotoxicity

Colistin is an antibiotic which is being used more commonly now than when it was introduced because of its activity against multiresistant Gram-negative bacteria, especially Acinetobacter baumanii and Enterobacteriaceae producing extended spectrum β-lactamases. It had a bad reputation due to reports of neurotoxicity and nephrotoxicity. Recent studies have shown lower rates of nephrotoxicity than previously reported. However, in one of these reports, 7/42 patients with high serum creatinine values prior to colistin treatment developed renal failure.

Uses

Polymyxin E (colistin) is a complex of closely related cyclic peptides E1 and E2, with additional minor analogues. Polymyxin E is produced by Bacillus polymyxa var. colistinus, and is a highly basic, atypical cyclic peptide which incorporates the unusual amino acid, diaminobutyric acid. Head-to-tail coupling of lysine completes the macrocycle. Balancing the polar cyclic peptide is a hydrophobic tail with short chain fatty acids. Polymyxin E is a broad spectrum antibiotic active against Gram negative bacteria. The mechanism of action involves disruption of the bacterial outer membrane by a detergent-like effect.

brand name

Coly-Mycin (Monarch).

COLISTIN Preparation Products And Raw materials

Raw materials

Colistin sulfate

Preparation Products

More

Less

COLISTIN Suppliers

China 65 Germany 1 India 3 South Korea 1 United Kingdom 3 United States 7 Global 80

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12338
Advantage: 58

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3750
Advantage: 55

ChemStrong Scientific Co.,Ltd

Tel: 0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17982
Advantage: 56

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9972
Advantage: 58

Alta Scientific Co., Ltd.

Tel: 022-6537-8550 15522853686
Fax: 022-2532-9655
Email: sales@altasci.com.cn
Country: China
ProdList: 4515
Advantage: 55

Raw material medicin reagent co.,Ltd

Tel: 025-57798860
Email: sales@njromanme.com
Country: China
ProdList: 4534
Advantage: 58

Lynnchem

Tel: 86-(0)29-85992781 17792393971
Email: info@lynnchem.com
Country: China
ProdList: 4587
Advantage: 58

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6870
Advantage: 58

Guangdong wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2815688 13927872512
Fax: 0751-8963795
Email: 3007421951@qq.com
Country: China
ProdList: 10084
Advantage: 58

More

Less

View Lastest Price from COLISTIN manufacturers

Hebei Duling International Trade Co. LTD

Product: COLISTIN 1066-17-7
Price: US $0.80/kg
Min. Order: 1kg
Purity: 99.95%HTCL
Supply Ability: 10Tons
Release date: 2023-04-11

Hebei Mojin Biotechnology Co., Ltd

Product: amoxicillin 1066-17-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-09-08

Hebei Guanlang Biotechnology Co., Ltd.

Product: amoxicillin 1066-17-7
Price: US $1.00/PCS
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2021-01-18

1066-17-7, COLISTINRelated Search:

TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) COLISTIN Cupric acetylacetonate Tris(2,4-pentanedionato)chroMiuM(III) 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE TERT-BUTYL ISOCYANIDE 2,4-PENTANEDIONE, SILVER DERIVATIVE METHYL ISOCYANOACETATE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Benzyl isocyanide Ferric acetylacetonate COBALT(II) ACETYLACETONATE N-BUTYLISOCYANIDE PHENYLSELENOL TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) Ethyl isocyanoacetate Aluminum acetylacetonate Tosylmethyl isocyanide

COLISTIN

colimycin

1264-72-8 (Sulfate)

Aids033059

Aids-033059

Colistin, ColiMycin M, BelcoMycin, ColyMycin, Torazin

PolyMyxin E coMplex

[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(1S,4S,7R,10S,13S,16S,19S)-4,13,16-tris(2-aminoethyl)-19-[(1R)-1-hydroxyethyl]-10-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-7-(phenylmethyl)-3,6

Polymyxin E1 sulfate

Polyoxin W.P.

colisticina

colomycin

coly-mycin

colymysins

kangdisu

kolimitsin

totazina

Colistin for system suitability

COLISTIN USP/EP/BP

1066-17-7

C58H90N16O8