Alantolactone

ChemicalBook > CAS DataBase List > Alantolactone

Product Name: Alantolactone
CAS No.: 546-43-0
Chemical Name: Alantolactone
Synonyms: HELENINE;ALANTOLACETONE;Alantolactone/Helenine;4a.H-Eudesma-5,11(13)-dien-12-oic acid, 8b-hydroxy-, g-lactone;helenin;Eupatal;NSC 93131;NSC 333843;Alant camphor;ALANTOLACTONE
CBNumber: CB0194433
Molecular Formula: C15H20O2
Formula Weight: 232.32
MOL File: 546-43-0.mol

Less

Alantolactone Property

Melting point:: 78-79 C
Boiling point:: 275 C
alpha: D +175° (chloroform)
Density: 1.0610 (rough estimate)
refractive index: 1.4360 (estimate)
storage temp.: -20°C
solubility: DMSO: soluble15mg/mL (clear solution)
form: powder
color: white to beige
Odor: Peculiar sweet-minty, slightly woody odor
LogP: 3.380
CAS DataBase Reference: 546-43-0(CAS DataBase Reference)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-43
Safety Statements: 26-36-36/37-24/25
WGK Germany: 3
HS Code: 29322090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0415
Product name: Alantolactone
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $67.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0415
Product name: Alantolactone
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $441
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHL89156
Product name: Alantolactone
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $430
Updated: 2024/03/01

Cayman Chemical

Product number: 29762
Product name: Alantolactone
Packaging: 5mg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 29762
Product name: Alantolactone
Packaging: 10mg
Price: $116
Updated: 2024/03/01

Less

Alantolactone Chemical Properties,Usage,Production

Description

The allergen eudesmanolide sesquiterpene lactone was isolated from elecampane (Inula helenium L.). With dehydrocostuslactone and costunolide, it is a component of the (sesquiterpene) lactone-mix, used to detect sensitization to Compositae.

Chemical Properties

Crystalline powder

Uses

anthelmintic, antibacterial, antineoplastic

Uses

Alantolactone has been used:

in cell viability assay
to examine the percentage of multicentrosomal mitosis in low and high passage human embryonic stem cells (hESC)
in assessment of degranulation

Uses

Alantolactone is sesquiterpene lactone that possesses anti-inflammatory property. Alantolactone have been studied to be developed as a novel agent against human liver cancer.

Definition

ChEBI: A sesquiterpene lactone that is 3a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2-one bearing two methyl substituents at positions 5 and 8a as well as a methylidene substituent at position 3.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Alantolactone is a sesquiterpene lactone disrupts the Cripto-1/ActRII complexes, resulting in an induction of activin/SMAD3 signaling. Alantolactone inhibits proliferation in cancer cells with no affect on normal cells.

Contact allergens

Solubility in organics

Soluble in alcohol and essential oils

storage

Store at -20°C

Alantolactone Preparation Products And Raw materials

Raw materials

Preparation Products

Less

Alantolactone Suppliers

Canada 2 China 235 Europe 3 France 1 Germany 2 India 2 South Korea 1 United Kingdom 7 United States 30 USA 1 Global 284

Huzhou ZhanShu Biotechnology Co.,Ltd

Tel: 0572-8889530 18167260939
Email: zsubio@163.com
Country: China
ProdList: 360
Advantage: 58

Nanjing Tengyi Biotechnology Co., Ltd

Tel: 025-58851786 17714337195
Email: sales@tybiochem.com
Country: China
ProdList: 6813
Advantage: 58

Zhuo Ruining (Shanghai) Technology Co., Ltd

Tel: 0086-18163338995; 18163338995
Email: 2605578685@qq.com
Country: China
ProdList: 495
Advantage: 58

Jiangsu Yongjian Pharmaceutical Technology Co., Ltd

Tel: 17701422015
Email: 3582572959@qq.com
Country: China
ProdList: 696
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: sales@jonln.com
Country: China
ProdList: 1995
Advantage: 65

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18207
Advantage: 66

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18738
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11707
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Aktin Chemicals, Inc.

Tel: 86-28-85159085
Fax: 86-28-85152372
Email: info@aktinchem.com
Country: China
ProdList: 297
Advantage: 62

Shenzhen Sungening Bio-Tech Co., Ltd

Tel: +86-0755-89668383
Fax: +86-0755-89594066/4038
Email: sales@sungening.com
Country: China
ProdList: 1319
Advantage: 65

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: meilunui@163.com
Country: China
ProdList: 4727
Advantage: 58

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5653
Advantage: 65

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4940
Advantage: 60

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Chengdu Climax Biotech Co., Ltd.

Tel: 028-83311324 1278112614
Fax: 028-83311324
Email: climaxbiotech@gmail.com
Country: China
ProdList: 925
Advantage: 58

Suzhou Sibian Chemical Technology Co.,Ltd.

Tel: 0512-65617459 18915409046
Fax: 0512-65617459
Email: sales@sibian-chem.com
Country: China
ProdList: 1922
Advantage: 55

Nanjing Spring & Autumn Biological Engineering Co., Ltd.

Tel: 025-84430028 13815430202
Email: sale02@cqherb.com
Country: China
ProdList: 281
Advantage: 59

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

Suzhou NeuPharma Co., Ltd.

Tel: 0512-62956991
Fax: 0512-67062860
Email: sales@neupharma.com
Country: China
ProdList: 40
Advantage: 65

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-400-6206333 18521732826
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9545
Advantage: 55

Shanghai Ruji Biology Technology Co., Ltd.

Tel: +86-21-65211385-8001 36031160
Fax: +86-21-65211385-8004
Email: sales@shruji.com
Country: China
ProdList: 3224
Advantage: 55

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8065
Advantage: 58

Cheng Du Pufeide Biotechnology Co., Ltd.

Tel: 028-82610909 13388174823
Fax: 8171-1798
Email: scglp@glp-china.com
Country: China
ProdList: 1064
Advantage: 58

Chengdu Herbpurify Co.Ltd.

Tel: 18302802153 18981717076
Fax: 086-28-85377358
Email: 2355253619@qq.com
Country: China
ProdList: 1104
Advantage: 58

Shanghai BeiZhuo Biotech Co., Ltd.

Tel: 021-61119791,13386096464
Fax: 021-50190009
Email: bzswkf@foxmail.com
Country: China
ProdList: 3921
Advantage: 50

Shanghai Zhanshu Chemical Technology Co., Ltd

Tel: +86-21-58589556
Fax: +86-21-58589557
Country: China
ProdList: 413
Advantage: 55

Shanghai Meishui Chemical Technology Co., Ltd

Tel: 021-60549325 18616193163
Fax: 021-33250306
Country: China
ProdList: 4526
Advantage: 56

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9978
Advantage: 55

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7887
Advantage: 56

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Shanghai Aspire Biological Technology Co., Ltd.

Tel: 021-61317773
Fax: 021-61486878
Email: sales@aspirebio.com
Country: China
ProdList: 2880
Advantage: 58

Shanghai CanSpecsci Instrument Co., Ltd.

Tel: 400-6087598 15021221957
Fax: 4006087598-8012
Email: order@canspecsci.com
Country: China
ProdList: 2045
Advantage: 56

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-+86-571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 11578
Advantage: 59

Shanghai Yongye Biotechnology Co., Ltd.

Tel: 86-021-61559134 15921386130
Fax: 021-55068248
Email: 3423497944@qq.com
Country: China
ProdList: 8144
Advantage: 55

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Wuhan ChemFaces Biochemical Co., Ltd.

Tel: 18607101326 15172504745
Fax: +86-27-84254680
Email: aileen@chemfaces.com
Country: China
ProdList: 7057
Advantage: 55

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 17687
Advantage: 55

Shanghai Xilong Biochemical Technology Co., Ltd.

Tel: 021-52907766-8042
Fax: 021-52906523
Country: China
ProdList: 9941
Advantage: 58

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3866
Advantage: 58

Shanghai QianYan Bio-technology Co., Ltd

Tel: 02781293128
Email: orders@biochemsafebuy.com
Country: China
ProdList: 9923
Advantage: 55

Less

View Lastest Price from Alantolactone manufacturers

Shaanxi Haibo Biotechnology Co., Ltd

Product: Alantolactone 546-43-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 2000ton
Release date: 2023-08-21

R&D Scientific Inc.

Product: Alantolactone 546-43-0
Price: US $580.00/g
Min. Order: 1g
Purity: 97
Supply Ability: 500 Kg
Release date: 2024-03-31

Anhui Ruihan Technology Co., Ltd

Product: Alantolactone 546-43-0
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 10000tons
Release date: 2023-08-22

546-43-0, AlantolactoneRelated Search:

ε-Caprolactone N,N-Dimethylacetamide ETHANE Dimethyl sebacate Dimethyl sulfate Dimethyl ether Dimethyl fumarate CHLOROPHOSPHONAZO III Dimethyl carbonate N,N-Dimethylformamide Dacthal Hyaluronic acid Dimethyl sulfoxide Dimethyl sulfone Ethyl 2-(Chlorosulfonyl)acetate Dichlorodimethylsilane Dimethyl sulfide Folic acid

HELENINE

8b-hydroxy-4ah-eudesm-5-en-12-oic acid

ALLANTOLACTONE

ALANTOLACETONE

ALANTOLACTONE

[3ar-(3aa,5b,8ab,9aa)]-3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylenenaphtho-[2,3-b]furan-2(3h)-one

[3aR-(3aalpha,5beta,8abeta,9aalpha)]-3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one

Alantolactone (Helenin)

helenin

4αH-Eudesma-5,11(13)-dien-12-oic acid, 8β-hydroxy-, γ-lactone (8CI)

Alant camphor

Alantolactone (6CI)

Elecampane camphor

Eupatal

Helenin (7CI)

Inula camphor

Naphtho[2,3-b]furan-2(3H)-one, 3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylene-, (3aR,5S,8aR,9aR)-

Naphtho[2,3-b]furan-2(3H)-one, 3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylene-, [3aR-(3aα,5β,8aβ,9aα)]-

NSC 93131

8b-hydroxy-4aH-eudesm-s-en-12-oic acid

Naphtho[2,3-b]furan-2(3H)-one,3a,5,6,7,8,8a,9,9a-

octahydro-5,8a-dimethyl-3-methylene-,(3aR,5S,8aR,9aR)-

4a.H-Eudesma-5,11(13)-dien-12-oic acid, 8b-hydroxy-, g-lactone

(3aR)-3a,5,6,7,8,8a,9,9aα-Octahydro-5β,8aβ-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one

(3aR)-3aα,5,6,7,8,8a,9,9aα-Octahydro-5β,8aβ-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one

ALANTOLACTONE(RG)

Alantolactone/Helenine

Alantic anhydride

NSC 333843

3aR,5S,8aR,9aR)-3a,5,6,7,8,8a,9,9a-Octahydro-5,8a-dimethyl-3-methylene-naphtho[2,3-b]furan-2(3H)-one

Alantolactone, 98%, from Inula helenium L.

(3aR,5S,8aR,9aR)-5,8a-Dimethyl-3-methylene-3,3a,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(5H)-one

Alantolactone USP/EP/BP

Alantolactone Inula camphor

3aR-(3a?,5?,8a?,9a?)]-3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one

(+)-Alantolactone

hymenolactone

Alantolactone-RM

546-43-0

Inhibitors

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Alkaloids

chiral