Alantolactone

Product Name: Alantolactone
CAS No.: 546-43-0
Chemical Name: Alantolactone
Synonyms: HELENINE;ALANTOLACETONE;Alantolactone/Helenine;4a.H-Eudesma-5,11(13)-dien-12-oic acid, 8b-hydroxy-, g-lactone;helenin;Eupatal;NSC 93131;NSC 333843;Alant camphor;ALANTOLACTONE
CBNumber: CB0194433
Molecular Formula: C15H20O2
Formula Weight: 232.32
MOL File: 546-43-0.mol

More

Less

Alantolactone Property

Melting point:: 78-79 C
Boiling point:: 275 C
alpha: D +175° (chloroform)
Density: 1.0610 (rough estimate)
refractive index: 1.4360 (estimate)
storage temp.: -20°C
solubility: DMSO: soluble15mg/mL (clear solution)
form: powder
color: white to beige
Odor: Peculiar sweet-minty, slightly woody odor
LogP: 3.380
CAS DataBase Reference: 546-43-0(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-43
Safety Statements: 26-36-36/37-24/25
WGK Germany: 3
HS Code: 29322090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0415
Product name: Alantolactone
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $67.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0415
Product name: Alantolactone
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $441
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHL89156
Product name: Alantolactone
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $430
Updated: 2024/03/01

Cayman Chemical

Product number: 29762
Product name: Alantolactone
Packaging: 5mg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 29762
Product name: Alantolactone
Packaging: 10mg
Price: $116
Updated: 2024/03/01

More

Less

Alantolactone Chemical Properties,Usage,Production

Description

The allergen eudesmanolide sesquiterpene lactone was isolated from elecampane (Inula helenium L.). With dehydrocostuslactone and costunolide, it is a component of the (sesquiterpene) lactone-mix, used to detect sensitization to Compositae.

Chemical Properties

Crystalline powder

Uses

anthelmintic, antibacterial, antineoplastic

Uses

Alantolactone has been used:

in cell viability assay
to examine the percentage of multicentrosomal mitosis in low and high passage human embryonic stem cells (hESC)
in assessment of degranulation

Uses

Alantolactone is sesquiterpene lactone that possesses anti-inflammatory property. Alantolactone have been studied to be developed as a novel agent against human liver cancer.

Definition

ChEBI: A sesquiterpene lactone that is 3a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2-one bearing two methyl substituents at positions 5 and 8a as well as a methylidene substituent at position 3.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Alantolactone is a sesquiterpene lactone disrupts the Cripto-1/ActRII complexes, resulting in an induction of activin/SMAD3 signaling. Alantolactone inhibits proliferation in cancer cells with no affect on normal cells.

Contact allergens

The allergen eudesmanolide sesquiterpene lactone was isolated from elecampane (Inula helenium L.). With dehydrocostuslactone and costunolide, it is a component of the (sesquiterpene) lactone mix used to detect sensitization to Compositae-Asteraceae.

Solubility in organics

Soluble in alcohol and essential oils

storage

Store at -20°C

Alantolactone Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Alantolactone Suppliers

Canada 2 China 235 Europe 3 France 1 Germany 2 India 2 South Korea 1 United Kingdom 7 United States 30 USA 1 Global 284

Huzhou ZhanShu Biotechnology Co.,Ltd

Tel: 0572-8889530 18167260939
Email: zsubio@163.com
Country: China
ProdList: 360
Advantage: 58

Nanjing Tengyi Biotechnology Co., Ltd

Tel: 025-58851786 17714337195
Email: sales@tybiochem.com
Country: China
ProdList: 6813
Advantage: 58

Zhuo Ruining (Shanghai) Technology Co., Ltd

Tel: 0086-18163338995; 18163338995
Email: 2605578685@qq.com
Country: China
ProdList: 495
Advantage: 58

Jiangsu Yongjian Pharmaceutical Technology Co., Ltd

Tel: 17701422015
Email: 3582572959@qq.com
Country: China
ProdList: 696
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: sales@jonln.com
Country: China
ProdList: 1995
Advantage: 65

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18207
Advantage: 66

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18738
Advantage: 57

More

Less

View Lastest Price from Alantolactone manufacturers

Shaanxi Haibo Biotechnology Co., Ltd

Product: Alantolactone 546-43-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 2000ton
Release date: 2023-08-21

R&D Scientific Inc.

Product: Alantolactone 546-43-0
Price: US $580.00/g
Min. Order: 1g
Purity: 97
Supply Ability: 500 Kg
Release date: 2024-03-31

Anhui Ruihan Technology Co., Ltd

Product: Alantolactone 546-43-0
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 10000tons
Release date: 2023-08-22

546-43-0, AlantolactoneRelated Search:

ε-Caprolactone N,N-Dimethylacetamide ETHANE Dimethyl sebacate Dimethyl sulfate Dimethyl ether Dimethyl fumarate CHLOROPHOSPHONAZO III Dimethyl carbonate N,N-Dimethylformamide Dacthal Hyaluronic acid Dimethyl sulfoxide Dimethyl sulfone Ethyl 2-(Chlorosulfonyl)acetate Dichlorodimethylsilane Dimethyl sulfide Folic acid

HELENINE

8b-hydroxy-4ah-eudesm-5-en-12-oic acid

ALLANTOLACTONE

ALANTOLACETONE

ALANTOLACTONE

[3ar-(3aa,5b,8ab,9aa)]-3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylenenaphtho-[2,3-b]furan-2(3h)-one

[3aR-(3aalpha,5beta,8abeta,9aalpha)]-3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one

Alantolactone (Helenin)

helenin

4αH-Eudesma-5,11(13)-dien-12-oic acid, 8β-hydroxy-, γ-lactone (8CI)

Alant camphor

Alantolactone (6CI)

Elecampane camphor

Eupatal

Helenin (7CI)

Inula camphor

Naphtho[2,3-b]furan-2(3H)-one, 3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylene-, (3aR,5S,8aR,9aR)-

Naphtho[2,3-b]furan-2(3H)-one, 3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylene-, [3aR-(3aα,5β,8aβ,9aα)]-

NSC 93131

8b-hydroxy-4aH-eudesm-s-en-12-oic acid

Naphtho[2,3-b]furan-2(3H)-one,3a,5,6,7,8,8a,9,9a-

octahydro-5,8a-dimethyl-3-methylene-,(3aR,5S,8aR,9aR)-

4a.H-Eudesma-5,11(13)-dien-12-oic acid, 8b-hydroxy-, g-lactone

(3aR)-3a,5,6,7,8,8a,9,9aα-Octahydro-5β,8aβ-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one

(3aR)-3aα,5,6,7,8,8a,9,9aα-Octahydro-5β,8aβ-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one

ALANTOLACTONE(RG)

Alantolactone/Helenine

Alantic anhydride

NSC 333843

3aR,5S,8aR,9aR)-3a,5,6,7,8,8a,9,9a-Octahydro-5,8a-dimethyl-3-methylene-naphtho[2,3-b]furan-2(3H)-one

Alantolactone, 98%, from Inula helenium L.

(3aR,5S,8aR,9aR)-5,8a-Dimethyl-3-methylene-3,3a,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(5H)-one

Alantolactone USP/EP/BP

Alantolactone Inula camphor

3aR-(3a?,5?,8a?,9a?)]-3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one

(+)-Alantolactone

hymenolactone

Alantolactone-RM

546-43-0

Inhibitors

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Alkaloids

chiral