14,15-LEUKOTRIENE C4

Product Name: 14,15-LEUKOTRIENE C4
CAS No.: 75290-60-7
Chemical Name: 14,15-LEUKOTRIENE C4
Synonyms: EXC4;EOXIN C4;14,15-LTC4;14,15-LEUKOTRIENE C4;OBQVBASHEWLKCQ-PKBWNXTMSA-N;Glycine, L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-13-carboxy-1-[(1S)-1-hydroxyhexyl]-2,4,6,9-tridecatetraen-1-yl]-L-cysteinyl-
CBNumber: CB0196624
Molecular Formula: C30H47N3O9S
Formula Weight: 625.77
MOL File: 75290-60-7.mol

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14,15-LEUKOTRIENE C4 Property

storage temp.: Store at -20°C
solubility: DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 100 μg/ml
form: Liquid.

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10011360
Product name: 14,15-Leukotriene C4
Purity: ≥95%
Packaging: 25μg
Price: $127
Updated: 2024/03/01

Cayman Chemical

Product number: 10011360
Product name: 14,15-Leukotriene C4
Purity: ≥95%
Packaging: 50μg
Price: $236
Updated: 2024/03/01

Cayman Chemical

Product number: 10011360
Product name: 14,15-Leukotriene C4
Purity: ≥95%
Packaging: 100μg
Price: $447
Updated: 2024/03/01

TRC

Product number: L330368
Product name: 14,15-LeukotrieneC4
Packaging: 25μg
Price: $125
Updated: 2021/12/16

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14,15-LEUKOTRIENE C4 Chemical Properties,Usage,Production

Description

Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. The majority of these metabolites are formed through the 5-lipoxygenase (5-LO) pathway. 14,15-LTC₄ is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-LOs on arachidonic acid via 15-HpETE and 14,15-LTA₄ intermediates. 14,15-LTC₄ is classified as an eoxin, because it is formed mostly by eosinophils. However, mast cells and nasal polyps can synthesize 14,15-LTC₄ as well. Little is known about the physiological actions of 14,15-LTC₄. It has weak contractile activity on both guinea pig ileum and pulmonary parenchyma in contrast to the effects of 5-LO-derived LTs. However, in an in vitro permeability assay, 14,15-LTC₄ can increase vascular permeability of human endothelial cell monolayers, with similar potency to that of 5-LO-derived LTs resulting in plasma leakage - a hallmark of inflammation.

Uses

14,15-Leukotriene C4 is an acute inflammatory mediator.

14,15-LEUKOTRIENE C4 Preparation Products And Raw materials

Raw materials

Preparation Products

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14,15-LEUKOTRIENE C4 Suppliers

China 23 Germany 1 United States 3 Global 27

Biomol Feinchemikalien GmbH

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Email: info@biomol.de
Country: Germany
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14,15-LEUKOTRIENE C4

14,15-LTC4

EOXIN C4

EXC4

OBQVBASHEWLKCQ-PKBWNXTMSA-N

Glycine, L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-13-carboxy-1-[(1S)-1-hydroxyhexyl]-2,4,6,9-tridecatetraen-1-yl]-L-cysteinyl-

75290-60-7