ChemicalBook > CAS DataBase List > VU-29

VU-29

Product Name
VU-29
CAS No.
890764-36-0
Chemical Name
VU-29
Synonyms
VU-29;VU-29/VU29;VU-29 ，S1970;VU-29, 10 mM in DMSO;N-(1,3-Diphenyl-1H-pyrazol-5-yl)-4-nitrobenzamide;N-(1,3-Diphenyl-1H-pyrazolo-5-yl)-4-nitrobenzamide;BenzaMide, N-(1,3-diphenyl-1H-pyrazol-5-yl)-4-nitro-;mGluR,hippocampal,inhibit,rat,LTP,VU29,potentiator,VU-29,allosteric,Metabotropic glutamate receptors,Inhibitor,LTD
CBNumber
CB02526230
Molecular Formula
C22H16N4O3
Formula Weight
384.39
MOL File
890764-36-0.mol
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VU-29 Property

Melting point:
221-223℃
Boiling point:
545.0±45.0 °C(Predicted)
Density 
1.30
storage temp. 
Store at RT
solubility 
Soluble to 100 mM in DMSO
form 
Powder
pka
11.17±0.70(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
4458
Product name
VU29
Purity
≥99%(HPLC)
Packaging
10
Price
$199
Updated
2021/12/16
Tocris
Product number
4458
Product name
VU29
Purity
≥99%(HPLC)
Packaging
50
Price
$738
Updated
2021/12/16
Usbiological
Product number
257073
Product name
VU 29
Packaging
10mg
Price
$466
Updated
2021/12/16
TRC
Product number
D678873
Product name
DPAP
Packaging
2.5mg
Price
$110
Updated
2021/12/16
ChemScene
Product number
CS-0028668
Product name
VU-29
Purity
98.04%
Packaging
5mg
Price
$100
Updated
2021/12/16
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VU-29 Chemical Properties,Usage,Production

Uses

DPAP is a potent, postive allosteric, potentiator at mGluR-5.

in vivo

VU-29 (500 nM) potentiates DHPG induced increases in phosphoinositide (PI) hydrolysis in rat hippocampal slices. VU-29 potentiates threshold TBS-induced long term potentiation (LTP) in rat hippocampal CA1 region. VU-29 (1 μM) potentiates chemically induced mGluR-long term depression (LTD) in area CA1 of the rat hippocampus. VU-29 (1 μM) potentiates stimulus-induced NMDA receptor-independent LTD[1].

IC 50

rat mGluR5: 9 nM (EC50); rat mGluR1: 557 nM (EC50); rat mGluR2: 1.5 μM (EC50); hmGluR4: 154 nM (EC50); rat mGluR5: 224 nM (Ki)

VU-29 Preparation Products And Raw materials

Raw materials

Preparation Products

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VU-29 Suppliers

China 57 The Netherlands 1 United Kingdom 1 United States 8 USA 1 Global 68
EMMX Biotechnology LLC
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888-539-0666
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888-539-0666
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info@emmx.com
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United States
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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021-65675885
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China
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Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
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China
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Tianjin Kailiqi Biotechnology Co., Ltd.
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15076683720
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022-23754520
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klq@cw-bio.com
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ShangHai Biochempartner Co.,Ltd
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2853530910@QQ.com
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China
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Shanghai Rechem science Co., Ltd.
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021-31433387 15618786686
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QQ:1369748377
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sales@rechemscience.com
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China
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Shanghai Chaolan Chemical Technology Center
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021-QQ：65489617 15618227136
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21-5161 9052
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China
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Beijing YiboYuntian Technology Co., Ltd.
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13811826434
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China
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Amatek Scientific Co. Ltd.
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0512-56316828
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China
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Aishilun biotechnology (Shanghai) co., LTD
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021-50676523 18019098996
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info@acelybio.com
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China
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890764-36-0, VU-29Related Search:

N-(4-Methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide VU0134992(hydrochloride) VU6005649 VU 591 hydrochloride VU0810464 VU0483605 N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide 1-(4-Methoxybenzyl)-5-trifluoromethoxyisatin VU 6008667 (1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide 5-Amino-3,4-dimethyl-thieno[2,3-c]pyridazine-6-carboxylic acid 4-trifluoromethanesulfonyl-benzylamide 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine VU 0360172 VU 0365114 VU 0357121 VU 0360223 VU 0364439 VU0650786

  • VU-29
  • BenzaMide, N-(1,3-diphenyl-1H-pyrazol-5-yl)-4-nitro-
  • N-(1,3-Diphenyl-1H-pyrazol-5-yl)-4-nitrobenzamide
  • N-(1,3-Diphenyl-1H-pyrazolo-5-yl)-4-nitrobenzamide
  • mGluR,hippocampal,inhibit,rat,LTP,VU29,potentiator,VU-29,allosteric,Metabotropic glutamate receptors,Inhibitor,LTD
  • VU-29/VU29
  • VU-29, 10 mM in DMSO
  • VU-29 ，S1970
  • 890764-36-0