ChemicalBook > CAS DataBase List > N3-PEG8-CH2CH2COOH

N3-PEG8-CH2CH2COOH

Product Name
N3-PEG8-CH2CH2COOH
CAS No.
1214319-92-2
Chemical Name
N3-PEG8-CH2CH2COOH
Synonyms
N3-PEG8-COOH;Azido-dPEG8-acid;Azido-dPEG??-acid;N3-PEG8-CH2CH2COOH;Azido-dPEG(R)8-acid;Azido-PEG8-CH2CH2COOH;Azido-PEG8-propionic acid;N3-PEG8-CH2CH2COOH/Propanoic acid, 3-[(23-azido-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]-
CBNumber
CB02713517
Molecular Formula
C19H37N3O10
Formula Weight
467.51118
MOL File
1214319-92-2.mol
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N3-PEG8-CH2CH2COOH Property

storage temp. 
-20°C
solubility 
Soluble in Water, DMSO, DCM, DMF
form 
solid or viscous liquid
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Safety

HS Code 
2929900090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
QBD10512
Product name
Azido-dPEG®8-acid
Packaging
100MG
Price
$305
Updated
2023/06/20
Sigma-Aldrich
Product number
QBD10512
Product name
Azido-dPEG®8-acid
Packaging
1000MG
Price
$1030
Updated
2023/06/20
American Custom Chemicals Corporation
Product number
LIN0000133
Product name
AZIDO-PEG8-ACID
Purity
95.00%
Packaging
500MG
Price
$1312.5
Updated
2021/12/16
BroadPharm
Product number
BP-21609
Product name
Azido-PEG8-acid
Purity
98%
Packaging
1g
Price
$700
Updated
2021/12/16
Activate Scientific
Product number
AS103899
Product name
N3-PEG8-CH2CH2COOH
Purity
95+%
Packaging
1g
Price
$848
Updated
2021/12/16
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N3-PEG8-CH2CH2COOH Chemical Properties,Usage,Production

Description

Azido-PEG8-acid is a aqueous soluble PEG linker containing an azide (N3) and a terminal carboxylic acid (CO2H) group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Biological Activity

N3-PEG8-CH2CH2COOH is a non-cleavable ADC linker containing 8-unit PEG that can be used to synthesize antibody drug conjugates (ADCs). It is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.

target

Non-cleavable

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PEGs

N3-PEG8-CH2CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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N3-PEG8-CH2CH2COOH Suppliers

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View Lastest Price from N3-PEG8-CH2CH2COOH manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
azido-PEG8-Acid 1214319-92-2
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-23

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  • N3-PEG8-CH2CH2COOH
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  • Azido-dPEG??-acid
  • Azido-PEG8-CH2CH2COOH
  • N3-PEG8-CH2CH2COOH/Propanoic acid, 3-[(23-azido-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]-
  • Azido-dPEG8-acid
  • 1214319-92-2
  • peg