ChemicalBook > CAS DataBase List > EPIDERMAL GROWTH FACTOR, HUMAN

EPIDERMAL GROWTH FACTOR, HUMAN

Product Name
EPIDERMAL GROWTH FACTOR, HUMAN
CAS No.
62229-50-9
Chemical Name
EPIDERMAL GROWTH FACTOR, HUMAN
Synonyms
EGP;URG;HEGF;MUC9;RHEGF;CHIT5;OVGP1;kutrol;Mucin 9;LONG EGF
CBNumber
CB0295101
Molecular Formula
C257H381N73O83S7
Formula Weight
6045.66934
MOL File
62229-50-9.mol
More
Less

EPIDERMAL GROWTH FACTOR, HUMAN Property

storage temp. 
-20°C
form 
powder
color 
white to off-white
CAS DataBase Reference
62229-50-9
More
Less

Safety

Hazard Codes 
B
WGK Germany 
3
RTECS 
KB4518000
F 
10-21
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E4127
Product name
Epidermal Growth Factor from murine submaxillary gland
Purity
EGF, suitable for cell culture
Packaging
0.1mg
Price
$183
Updated
2024/03/01
Sigma-Aldrich
Product number
E4127
Product name
Epidermal Growth Factor from murine submaxillary gland
Purity
EGF, suitable for cell culture
Packaging
5x0.1mg
Price
$711
Updated
2024/03/01
Sigma-Aldrich
Product number
E1257
Product name
Epidermal Growth Factor from murine submaxillary gland
Purity
lyophilized powder, BioReagent, suitable for cell culture
Packaging
0.1mg
Price
$386
Updated
2024/03/01
Sigma-Aldrich
Product number
324831
Product name
EGF, Human, Recombinant, E. coli
Packaging
200μg
Price
$337
Updated
2024/03/01
Cayman Chemical
Product number
32057
Product name
EGF (human, recombinant)
Packaging
100μg
Price
$64
Updated
2024/03/01
More
Less

EPIDERMAL GROWTH FACTOR, HUMAN Chemical Properties,Usage,Production

Description

Epidermal growth factor (EGF) is a polypeptide ligand for the EGF receptor (EGFR; ). It is synthesized as a 1,217 amino acid glycosylated transmembrane precursor protein from which mature, soluble EGF is formed by proteolysis. Mature EGF is a 53-amino acid polypeptide that contains six cysteine residues, which form three intramolecular disulfide bonds essential to the biological activity of EGF. EGF is synthesized in the brain, kidney, pancreas, small intestine, pituitary gland, and submaxillary gland and is found in various bodily fluids, including saliva, cerebrospinal fluid, blood, breast milk, and prostatic fluid. Binding of EGF to the EGFR induces receptor dimerization, autophosphorylation, and intracellular signaling with roles in cell proliferation. In patients with early Parkinson’s disease and Alzheimer’s disease with amnestic mild cognitive impairment, low plasma EGF levels are predictive of future long-term cognitive decline. Plasma levels of EGF are reduced in pregnant woman infected with T. cruzi compared with uninfected pregnant controls. Exogenous application of EGF normalizes cortical GABAergic transmission and improves rotarod performance in the R6/2 transgenic mouse model of Huntington''s disease. Probiotic administration of E. coli engineered to secrete human EGF induces epithelial barrier restoration in a mouse model of intestinal ulcers. Immunization with human EGF induces an anti-EGF antibody response and increased survival in mice with EGFR-expressing tumors. Cayman''s EGF (human, recombinant) protein can be used for cell-based assay applications. This protein consists of 54 amino acids and has a calculated molecular mass of 6.3 kDa.

Uses

Epidermal Growth Factor (EGF) from murine submaxillary gland has been used as a mitogen, triggering the cell to commence mitosis, in a variety of cell lines. In tissue cultures, EGF acts to reduce or eliminate the requirement for serum and can be used in conjunction with other media additives and hormone. The working concentration for EGF is generally 0.1-10 ng/mL.

General Description

EGF (epidermal growth factor) is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Recombinant murine EGF is a 6kDa globular protein containing 53 amino acid residues, including 3 intramolecular disulfide-bonds.

Biochem/physiol Actions

EGF (epidermal growth factor) has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF (transforming growth factor)-α and VGF (vaccinia virus growth factor). EGF plays an important role in embryogenesis and cardiogenesis.

EPIDERMAL GROWTH FACTOR, HUMAN Preparation Products And Raw materials

Raw materials

Freeze-dried powder TRIS BORATE EDTA BUFFER, 10X, DNASE, RNASE AND PROTEASE FREE, PH 8.3, FOR MOLECULAR BIOLOGY

Preparation Products

More
Less

EPIDERMAL GROWTH FACTOR, HUMAN Suppliers

China 61 Europe 2 Germany 1 Switzerland 1 United Kingdom 2 United States 6 Global 73
ACROBiosystems
Tel
18514007688
Email
jiaxin.zhao@acrobiosystems.com
Country
China
ProdList
694
Advantage
58
Shanghai Hanhong Scientific Co.,Ltd.
Tel
Country
China
ProdList
42982
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15421
Advantage
60
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9503
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5503
Advantage
55
Jinan Yaoyan Pharmaceutical Co., Ltd.
Tel
Fax
-
Email
jnyaoyan@163.com
Country
China
ProdList
3069
Advantage
58
Beijing OKA biological technology co., LTD
Tel
010-010-62971590 18548936886
Fax
010-62340519
Email
3462612863@qq.com
Country
China
ProdList
6912
Advantage
58
Nanjing Nuosu Technology Co., Ltd.
Tel
13921443466
Email
13921443466@139.com
Country
China
ProdList
100
Advantage
58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19105
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-029-89586680 +86-18192503167
Fax
+86-29-88380327
Email
1026@dideu.com
Country
China
ProdList
9126
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-61398051 +8613650506873
Email
sales@chemdad.com
Country
China
ProdList
39916
Advantage
58
Absin Bioscience Inc.
Tel
021-38015121 15000105423
Email
chenjw@absin.cn
Country
China
ProdList
24734
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8141
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44941
Advantage
58
Lingyuan Bebiansen Biological Technology Co., Ltd
Tel
18642120371
Email
2837458851@qq.com
Country
China
ProdList
9925
Advantage
58
Mainchem Co., Ltd.
Tel
--
Fax
--
Email
sarah@mainchem.com
Country
China
ProdList
6572
Advantage
58
Shanghai fantai biology science and technology co., ltd
Tel
15601885736
Email
2114786541@qq.com
Country
China
ProdList
206
Advantage
58
Guangzhou Yunmen Biotechnology Co., Ltd
Tel
18902340307 18902340307
Fax
0751-2819901
Email
3356812514@qq.com
Country
China
ProdList
9242
Advantage
58
ChemeGen 中国
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
6975
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2815987 13927875076
Fax
0751-2828607
Email
3007432263@qq.com
Country
China
ProdList
9978
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
13675144456
Email
alan.chow@synzest.com
Country
China
ProdList
9471
Advantage
58
JiangSu Star Science Co.,Ltd
Tel
400-605-7200 17312445705
Email
sales022@b2star.com
Country
China
ProdList
3764
Advantage
58
Qiyuan (Guangdong) Pharmaceutical Chemical Co., Ltd.
Tel
400-666-9280 18026564465
Email
304903156@qq.com
Country
China
ProdList
8011
Advantage
58
Guangdong Fangxin Biotechnology Co., Ltd.
Tel
0751-2838688 13376594225
Email
1276075424@qq.com
Country
China
ProdList
9931
Advantage
58
Nanjing Yushengkang Biotechnology Co., Ltd
Tel
13327808530
Email
2670965693@qq.com
Country
China
ProdList
2179
Advantage
58
Henan Tianfu Chemical Co.,Ltd.
Tel
+86-0371-55170693 +86-19937530512
Fax
0371-55170693
Email
info@tianfuchem.com
Country
China
ProdList
21689
Advantage
55
career henan chemical co
Tel
+86-0371-86658258
Email
sales@coreychem.com
Country
China
ProdList
29914
Advantage
58
Wuhan Quanjinci New Material Co.,Ltd.
Tel
+8615271838296
Email
kyra@quanjinci.com
Country
China
ProdList
1534
Advantage
58
GIHI CHEMICALS CO.,LIMITED
Tel
+8618058761490
Email
info@gihichemicals.com
Country
China
ProdList
50000
Advantage
58
Hebei Duling International Trade Co. LTD
Tel
+8618712993135
Fax
0311-87836622
Email
sales01@hbduling.cn
Country
China
ProdList
15741
Advantage
58
Dongguan Biaobiao Experimental Equipment Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6673
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
shxiyuanbio@163.com
Country
CHINA
ProdList
6921
Advantage
58
Shanghai Shanran Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
shanranbio@163.com
Country
CHINA
ProdList
1563
Advantage
58
asiapeptide
Tel
--
Fax
--
Email
frog5235@peptide-search.com
Country
China
ProdList
1367
Advantage
58
Shanghai Shifeng Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
2279790755@qq.com
Country
CHINA
ProdList
5572
Advantage
58
Shanghai yiji industries Co., Ltd.
Tel
--
Fax
--
Email
yiji01@foxmail.com
Country
China
ProdList
6294
Advantage
50
Boao Pike
Tel
--
Fax
--
Email
lyn@biopike.com.cn
Country
CHINA
ProdList
6629
Advantage
58
BEIJING BIOSYNTHESIS BIOTECHNOLOGY CO., LTD.
Tel
--
Fax
--
Email
sales@bioss.com.cn
Country
CHINA
ProdList
6717
Advantage
58
Shanghai Benrui Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
john.st@163.com
Country
CHINA
ProdList
1472
Advantage
58
Beijing baierdi biotechnology co. LTD
Tel
--
Fax
--
Email
biodee2012@126.com
Country
CHINA
ProdList
1773
Advantage
58
Shanghai Lianshuobao is Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
lianshuobio@163.com
Country
CHINA
ProdList
6985
Advantage
58
Shanghai Yuqi Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
847627550@qq.com
Country
CHINA
ProdList
6087
Advantage
58
Shenzhen Kerunda Biological Engineering Co., Ltd.
Tel
--
Fax
--
Email
kerunda@163.com
Country
CHINA
ProdList
75
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6846
Advantage
58
Shanghai Yuda Industrial Co., Ltd.
Tel
--
Fax
--
Email
lucy@runwelltac.com
Country
CHINA
ProdList
6107
Advantage
58
Shanghai Huzhen Industrial Co., Ltd.
Tel
--
Fax
--
Email
shhzsw01@163.com
Country
CHINA
ProdList
6480
Advantage
58
Nanjing Sai Ruirui Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
sales@shrbio.com
Country
CHINA
ProdList
6873
Advantage
58
XI'AN VEDA CHEMICAL CO. LTD
Tel
--
Fax
--
Email
sales@vedachem.com
Country
China
ProdList
93
Advantage
50
Guangzhou WeiBo Chemical Co., Ltd.
Tel
--
Fax
--
Email
weibochem@163.com
Country
China
ProdList
6187
Advantage
67
More
Less

View Lastest Price from EPIDERMAL GROWTH FACTOR, HUMAN manufacturers

Hebei Duling International Trade Co. LTD
Product
EPIDERMAL GROWTH FACTOR, HUMAN 62229-50-9
Price
US $50.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1
Release date
2022-09-19
Wuhan Quanjinci New Material Co.,Ltd.
Product
EPIDERMAL GROWTH FACTOR, HUMAN 62229-50-9
Price
US $70.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
1000000tons
Release date
2023-10-30
Career Henan Chemical Co
Product
EPIDERMAL GROWTH FACTOR, HUMAN 62229-50-9
Price
US $8.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
10MT
Release date
2018-12-16

62229-50-9, EPIDERMAL GROWTH FACTOR, HUMANRelated Search:

Tris(2,4-pentanedionato)chroMiuM(III) Tosylmethyl isocyanide Cupric acetylacetonate Ethyl isocyanoacetate 2,4-PENTANEDIONE, SILVER DERIVATIVE Aluminum acetylacetonate METHYL ISOCYANOACETATE COBALT(II) ACETYLACETONATE Ferric acetylacetonate DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) N-BUTYLISOCYANIDE 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE SALCOMINE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Benzyl isocyanide TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) TERT-BUTYL ISOCYANIDE Epidermal Growth Factor Human Egf Human Epidermal Growth Factor

  • RHEGF
  • REC EGF (HUMAN)
  • REC EPIDERMAL GROWTH FACTOR (HUMAN)
  • RECOMBINANT HUMAN EGF
  • LONG EGF
  • ASN-SER-ASP-SER-GLU-CYS-PRO-LEU-SER-HIS-ASP-GLY-TYR-CYS-LEU-HIS-ASP-GLY-VAL-CYS-MET-TYR-ILE-GLU-ALA-LEU-ASP-LYS-TYR-ALA-CYS-ASN-CYS-VAL-VAL-GLY-TYR-ILE-GLY-GLU-ARG-CYS-GLN-TYR-ARG-ASP-LEU-LYS-TRP-TRP-GLU-LEU-ARG
  • EGF, HUMAN
  • EGP
  • EPIDERMAL GROWTH FACTOR, HUMAN, RECOMBINANT
  • EPIDERMAL GROWTH FACTOR, HUMAN
  • EPIDERMAL GROWTH FACTOR (EGF) HUMAN
  • HUMAN EGF
  • HUMAN EPIDERMAL GROWTH FACTOR
  • HUMAN URG
  • HUMAN UROGASTRONE
  • HEGF
  • antheloneu
  • urogastrone
  • Epidermal Growth Factor, Murine Submaxillary Glands, Recpt.
  • mouse epidermal growth factor (egf)
  • urogastrone from human pregnancy urine
  • LONGEGF MEDIA GRADE
  • LONG EGF, RECOMBINANT ANALOG
  • LONG(TM) EGF, MEDIA GRADE
  • EPIDERMAL GROWTH FACTOR FROM MOUSE*SUBMA XILLARY GLA
  • EPIDERMAL GROWTH FACTOR (FROM MOUSE SUBMAXILLARY GLAND) 95%
  • EPIDERMAL GROWTH FACTOR 98+%, LYOPHILIZED
  • EPIDERMAL GROWTH FACTOR 95+%
  • EPIDERMAL GROWTH FACTOR FROM RAT SUBMANDIBULAR GLANDS
  • EPIDERMAL GROWTH FACTOR HUMAN, RECOMBINANT 98+%
  • EGF, Epidermal cell growth factor
  • Epidermal Growth Factor from murine submaxillary gland
  • Anthelone
  • EGF (Recombinant Human Epidermal Growth Factor)
  • Epidemal Growth Factor Human from Mouse
  • CHIT5
  • MUC9
  • Mucin 9
  • OVGP1
  • Epidermal cell growth factor
  • Epidermal Growth Factor from murine submaxillary gland,EGF, Epidermal cell growth factor
  • EGF, Human, Recombinant, E. coli
  • Fc-tagged)
  • Soluble CD40 Ligand (human, recombinant
  • epidermalgrowthfactor(egf)
  • epidermalgrowthfactorreceptorgrade*frommouse
  • epidermalgrowthfactor-urogastrone
  • kutrol
  • uroanthelone
  • uroenterone
  • urogastron
  • uro-gastron
  • Oviductal glycoprotein
  • EGF, Murine Submaxillary Glands, Receptor Grade
  • EGF, Human, Recombinant,
  • LONG EGF human
  • URG
  • EGF from mouse