Bromo-PEG2-t-butyl ester
- Product Name
- Bromo-PEG2-t-butyl ester
- CAS No.
- 1381861-91-1
- Chemical Name
- Bromo-PEG2-t-butyl ester
- Synonyms
- Br-PEG2-COOtBu;CAS_1381861-91-1;Bromo-PEG2-C2-Boc;Br-PEG2-CH2CH2COOtBu;Br-PEG2-t-butyl ester;Bromo-PEG3-t-butyl ester;Bromo-PEG2-t-butyl ester;Bromo-PEG2-tert-butyl Ester;tert-Butyl 3-(2-(2-bromoethoxy)ethoxy)propanoate;Propanoic acid, 3-[2-(2-bromoethoxy)ethoxy]-, 1,1-dimethylethyl ester
- CBNumber
- CB03048715
- Molecular Formula
- C11H21BrO4
- Formula Weight
- 297.19
- MOL File
- 1381861-91-1.mol
Bromo-PEG2-t-butyl ester Property
- Boiling point:
- 332.0±22.0 °C(Predicted)
- Density
- 1.240±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- Liquid
- color
- Colorless to light yellow
- InChI
- InChI=1S/C11H21BrO4/c1-11(2,3)16-10(13)4-6-14-8-9-15-7-5-12/h4-9H2,1-3H3
- InChIKey
- UOYAYHGUAATLSG-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)CCOCCOCCBr
Safety
- HS Code
- 2942000090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B800375
- Product name
- Bromo-Peg2-T-ButylEster
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- BIPG1348
- Product name
- Bromo-PEG2-t-butyl ester
- Packaging
- 250mg
- Price
- $546
- Updated
- 2021/12/16
- Product number
- BIPG1349
- Product name
- Bromo-PEG3-t-butyl ester
- Packaging
- 250mg
- Price
- $546
- Updated
- 2021/12/16
- Product number
- BP-20681
- Product name
- Bromo-PEG2-t-butylester
- Purity
- 98%
- Packaging
- 1g
- Price
- $750
- Updated
- 2021/12/16
- Product number
- BP-20681
- Product name
- Bromo-PEG2-t-butylester
- Purity
- 98%
- Packaging
- 5G
- Price
- $1540
- Updated
- 2021/12/16
Bromo-PEG2-t-butyl ester Chemical Properties,Usage,Production
Description
Bromo-PEG2-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
Bromo-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromo-PEG2-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Bromo-PEG2-t-butyl ester Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
View Lastest Price from Bromo-PEG2-t-butyl ester manufacturers
- Product
- Br-PEG2-COOtBu 1381861-91-1
- Price
- US $0.00/g
- Min. Order
- 25g
- Purity
- >98.00%
- Supply Ability
- 25g
- Release date
- 2024-03-25
- Product
- Bromo-PEG2-t-butyl ester 1381861-91-1
- Price
- US $2.00/g
- Min. Order
- 1g
- Purity
- 95~99.9%
- Supply Ability
- 5KG
- Release date
- 2020-03-05