ChemicalBook > CAS DataBase List > Bromo-PEG1-CH2CO2H

Bromo-PEG1-CH2CO2H

Product Name: Bromo-PEG1-CH2CO2H
CAS No.: 1135131-50-8
Chemical Name: Bromo-PEG1-CH2CO2H
Synonyms: CAS_1135131-50-8;Bromo-PEG1-CH2COOH;Bromo-PEG7-CH2CO2H;Bromo-PEG1-CH2CO2H;Bromo-PEG1-acetic acid;(2-Bromo-ethoxy)-acetic acid;2-(2-Bromoethoxy)acetic acid;Acetic acid, 2-(2-bromoethoxy)-;Bromo-PEG1-acetic acid,Bromo-PEG1-CH2CO2H
CBNumber: CB03062436
Molecular Formula: C4H7BrO3
Formula Weight: 183
MOL File: 1135131-50-8.mol

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Bromo-PEG1-CH2CO2H Property

Boiling point:: 316.4±17.0 °C(Predicted)
Density: 1.683±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
form: Solid-Liquid Mixture
pka: 3.31±0.10(Predicted)
color: Colorless to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B750460
Product name: Bromo-PEG1-ch2co2h
Packaging: 10mg
Price: $90
Updated: 2021/12/16

BroadPharm

Product number: BP-22284
Product name: Bromo-PEG1-CH2CO2H
Purity: 98%
Packaging: 100mg
Price: $330
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1337
Product name: Bromo-PEG1-CH2CO2H
Packaging: 100mg
Price: $643
Updated: 2021/12/16

BroadPharm

Product number: BP-22284
Product name: Bromo-PEG1-CH2CO2H
Purity: 98%
Packaging: 500mg
Price: $660
Updated: 2021/12/16

BroadPharm

Product number: BP-22284
Product name: Bromo-PEG1-CH2CO2H
Purity: 98%
Packaging: 1g
Price: $980
Updated: 2021/12/16

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Bromo-PEG1-CH2CO2H Chemical Properties,Usage,Production

Description

Bromo-PEG1-CH2CO2H is a PEG linker containing a bromide group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions.

Uses

Bromo-PEG1-CH2COOH is a PROTAC linker can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] Christopher Michael Semko, et al. C26-linked rapamycin analogs as mtor inhibitors. WO2019212991A1.

Bromo-PEG1-CH2CO2H Preparation Products And Raw materials

Raw materials

Preparation Products

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1135131-50-8, Bromo-PEG1-CH2CO2HRelated Search:

Br-PEG6-bromide Bromoacetamido-PEG3-t-Butyl Ester Bromo-PEG2-phosphonic acid ethyl ester Bromo-PEG5-Azide Bromo-PEG4-Azide Bromoacetamido-PEG4-t-Butyl Ester Br-PEG5-CH2COOH 3-(2-hydroxyethoxy)propanoic acid beta-hydroxyethoxyacetic acid 2-(2-hydroxyethoxy)ethyl acetate Br-PEG5-acid Bromo-PEG1-Acid Bromo-PEG1-t-butyl ester Bromo-PEG2-t-butyl ester Bromo-PEG4-t-butyl ester Bromo-PEG2-phosphonic acid Bromoacetamido-PEG5-DOTA Bromoacetamido-PEG2-AZD

Bromo-PEG1-CH2CO2H

Bromo-PEG7-CH2CO2H

Bromo-PEG1-CH2COOH

(2-Bromo-ethoxy)-acetic acid

Bromo-PEG1-acetic acid

CAS_1135131-50-8

Bromo-PEG1-acetic acid,Bromo-PEG1-CH2CO2H

Acetic acid, 2-(2-bromoethoxy)-

2-(2-Bromoethoxy)acetic acid

1135131-50-8