ChemicalBook > CAS DataBase List > 4-Methylanisole

4-Methylanisole

Product Name
4-Methylanisole
CAS No.
104-93-8
Chemical Name
4-Methylanisole
Synonyms
MSO;1-METHOXY-4-METHYLBENZENE;P-CRESYL METHYL ETHER;PARA CRESYL METHYL ETHER;P-METHYLANISOLE;4-METHOXYTOLUENE;P-CRESOL METHYL ETHER;Benzene,1-methoxy-4-methyl-;FEMA 2681;MSO)4-Methylan
CBNumber
CB0327875
Molecular Formula
C8H10O
Formula Weight
122.16
MOL File
104-93-8.mol
More
Less

4-Methylanisole Property

Melting point:
-32°C
Boiling point:
174 °C(lit.)
Density 
0.969 g/mL at 25 °C(lit.)
vapor pressure 
5.25 mm Hg ( 50 °C)
refractive index 
n20/D 1.511(lit.)
FEMA 
2681 | P-METHYLANISOLE
Flash point:
128 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Soluble), Ethyl Acetate (Slightly)
form 
Liquid
color 
Clear colorless to slightly yellow
Odor
at 1.00 % in dipropylene glycol. naphthyl cresol ylang powdery nutty
Odor Type
naphthyl
Odor Threshold
0.0012ppm
explosive limit
1.1-8.3%(V)
Water Solubility 
slightly soluble
λmax
279nm(MeOH)(lit.)
JECFA Number
1243
BRN 
1237336
Dielectric constant
4.0300000000000002
Stability:
Stable. Incompatible with strong oxidizing agents. Combustible.
LogP
2.74-2.8 at 25-35℃
CAS DataBase Reference
104-93-8(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, 1-methoxy-4-methyl-(104-93-8)
EPA Substance Registry System
p-Methylanisole (104-93-8)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-38-10-52/53-63
Safety Statements 
36/37-16-61
RIDADR 
UN 1993 3/PG 3
WGK Germany 
1
RTECS 
BZ8780000
TSCA 
Yes
HazardClass 
3
PackingGroup 
III
HS Code 
29093090
Hazardous Substances Data
104-93-8(Hazardous Substances Data)
Toxicity
The acute oral LD50 in rats was reported as 1.92 (1.51-2.45) g/kg (Hart, 1971). The acute dermal LD50 in rabbits was reported as > 5 g/kg (Hart, 1971).
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H315Causes skin irritation

H361Suspected of damaging fertility or the unborn child

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P308+P313IF exposed or concerned: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
148091
Product name
4-Methylanisole
Purity
99%
Packaging
100ml
Price
$25.5
Updated
2024/03/01
Sigma-Aldrich
Product number
148091
Product name
4-Methylanisole
Purity
99%
Packaging
1l
Price
$157
Updated
2024/03/01
TCI Chemical
Product number
M0149
Product name
4-Methoxytoluene
Purity
>98.0%(GC)
Packaging
25mL
Price
$18
Updated
2024/03/01
TCI Chemical
Product number
M0149
Product name
4-Methoxytoluene
Purity
>98.0%(GC)
Packaging
100mL
Price
$28
Updated
2024/03/01
Alfa Aesar
Product number
A11572
Product name
4-Methylanisole, 99%
Packaging
500ml
Price
$63.65
Updated
2024/03/01
More
Less

4-Methylanisole Chemical Properties,Usage,Production

Description

p-Methylanisole has a pungent odor suggestive of ylang-ylang. May be prepared by methylation of p-cresol.

Chemical Properties

p-Methylanisole has a pungent odor suggestive of ylang-ylang.

Chemical Properties

colourless liquid

Occurrence

Reported found in the oils of ylang-ylang, cananga and flowers of Mimusops elengi L. Also reported found in tomato, blue and Camembert cheese, starfruit, buckwheat, rooibus tea (Aspalathus linearis) and tapereba (Spondias lutea).

Uses

4-Methylanisole was used to prepare 5-methoxy-1,8-dimethyltetralin. It was also used as the solubilizate molecule to study the site of incorporation of solubilizates in sodium dodecyl sulfate (SDS) micellar systems.

Uses

4-Methylanisole may be used as an analytical standard for the determination of the analyte in Malus taxa flowers, coffee brews, aqueous matrices, food products, and Ficus semicordata by various chromatography techniques.

Uses

Perfumery, flavoring.

Preparation

By methylation of p-cresol.

Definition

ChEBI: 1-Methoxy-4-methylbenzene is a member of methoxybenzenes.

Aroma threshold values

Detection: 200 ppb

Taste threshold values

Taste characteristics at 20 ppm: naphthyl, phenolic, camphoraceous, cooling and woody.

Synthesis Reference(s)

Journal of the American Chemical Society, 113, p. 8516, 1991 DOI: 10.1021/ja00022a046
Tetrahedron Letters, 32, p. 2759, 1991 DOI: 10.1016/0040-4039(91)85078-J
The Journal of Organic Chemistry, 59, p. 4687, 1994 DOI: 10.1021/jo00095a054

General Description

4-Methylanisole is an odorant benzenoid belonging to the group of volatile organic compounds (VOCs). It can contribute to the floral scent of the plants. 4-Methylanisole is typically a lignin-derived bio-oil that is also a major ingredient of certain food products.

Safety Profile

Moderately toxic by ingestion. A skin irritant. Flammable liquid when exposed to heat, sparks, or flame. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

Dissolve 4-methyl anisole in diethyl ether, wash it with M NaOH, water, dry (Na2CO3), evaporate and distil it under vacuum. The picrate has m 103o (from aqueous EtOH). [Beilstein 6 IV 2098.]

4-Methylanisole Preparation Products And Raw materials

Raw materials

p-Cresol 2-Methylanisole

Preparation Products

Acid Orange 156 2-Methoxy-5-methylaniline VESNARINONE p-Anisaldehyde
More
Less

4-Methylanisole Suppliers

Americas 1 Australia 1 Belgium 2 Canada 3 China 286 Europe 3 Germany 6 India 69 Italy 2 Japan 6 Mexico 1 Slovakia 1 South Korea 1 Spain 2 Switzerland 3 Ukraine 1 United Kingdom 8 United States 56 USA 1 Global 453
HUAIAN DEPON CHEMICAL CO., LTD.
Tel
0517-82332538 13852381548
Fax
0517-82332537
Email
sales@deponchem.com
Country
China
ProdList
9
Advantage
12
Shaanxi Coal Chemical Industry Technology Research Institute Co., Ltd.
Tel
029-81772051 15388612296
Email
549981688@qq.com
Country
China
ProdList
29
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7583
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12458
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17987
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
jiliang chemicals
Tel
21-62165282 15801962796;
Fax
021 61153784
Email
bidingchem@163.com
Country
China
ProdList
1165
Advantage
60
XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-0712-2580635 15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Beijing Isomersyn Technology CO;LTD
Tel
010-82954736 13391601435
Email
sales@isomersyn.com
Country
China
ProdList
3296
Advantage
57
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7815
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4388
Advantage
65
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9725
Advantage
55
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
4974
Advantage
50
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9872
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6139
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9442
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19918
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18216
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9552
Advantage
55
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4576
Advantage
55
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3933
Advantage
58
Shanghai BeiZhuo Biotech Co., Ltd.
Tel
021-61119791,13386096464
Fax
021-50190009
Email
bzswkf@foxmail.com
Country
China
ProdList
3924
Advantage
50
Shanghai Meishui Chemical Technology Co., Ltd
Tel
021-60549325 18616193163
Fax
021-33250306
Country
China
ProdList
4528
Advantage
56
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai DiBai Chemicals Co., Ltd.
Tel
021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3993
Advantage
60
RiZhao LiDeShi Chemical Co., Ltd.
Tel
010-51268198
Fax
010-63833209
Email
leadershipchem@126.com
Country
China
ProdList
2549
Advantage
58
Mei Lan Industrial (Shanghai) Co., Ltd.
Tel
021-58958189
Fax
021-58957967
Email
wouchina@126.com
Country
China
ProdList
2671
Advantage
55
Shanghai GaoLang Chemical Technology Co., Ltd.
Tel
021-57340939 18017297327
Fax
021-37210791
Email
sales@gaolangchemical.com
Country
China
ProdList
888
Advantage
55
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17982
Advantage
56
Shanghai ideal Industrial Co., Ltd.
Tel
021-58957966 18930537195
Fax
021-60899437
Email
wouchina@126.com
Country
China
ProdList
3033
Advantage
58
GuangTuo Chemical (Shanghai) Co., Ltd.
Tel
021-60899189-8001 18918189673
Fax
021-60899304
Email
gtchem@126.com
Country
China
ProdList
2661
Advantage
58
Beijing FYF Chemicals Co., Ltd
Tel
010-61647239; 15318973357
Fax
010-57903446
Email
1460285141@qq.com
Country
China
ProdList
2948
Advantage
58
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5223
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
More
Less

View Lastest Price from 4-Methylanisole manufacturers

airuikechemical co., ltd.
Product
4-methylanisole 104-93-8
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.99%
Supply Ability
200tons
Release date
2024-04-07
Hebei Duling International Trade Co. LTD
Product
4-Methylanisole 104-93-8
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 Ton
Release date
2022-11-16
Hebei Yanxi Chemical Co., Ltd.
Product
4-Methylanisole 104-93-8
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-10-09

104-93-8, 4-MethylanisoleRelated Search:

Anise oil 4-(Trifluoromethoxy)aniline Tribenuron methyl Kresoxim-methyl Thiophanate-methyl p-Tolunitrile 4-Methoxybenzylchloride Methyl salicylate o-Dianisidine 4-Methoxyphenylacetone p-Anisidine Tosyl chloride Methyl acetate p-Toluenesulfonamide p-Anisaldehyde Anisole p-Toluic acid 4-Methoxyphenylacetic acid

  • FEMA 2681
  • 1-METHOXY-4-METHYLBENZENE
  • METHYL-P-CRESOL
  • METHYL P-TOLYL ETHER
  • 4-METHYLANISOLE
  • 4-METHOXYTOLUENE
  • MSO
  • P-CRESYL METHYL ETHER
  • P-CRESOL METHYL ETHER
  • PARA CRESYL METHYL ETHER
  • P-METHYL TOLYL ETHER
  • P-METHOXYTOLUENE
  • P-METHYLANISOLE
  • 1-methoxy-4-methyl-benzen
  • 1-Methyl-4-methoxybenzene
  • 4-METHYLANISOLE 99+% FCC
  • 4-Methoxytoluol
  • KRESOLMETHYLETHER-PARA
  • 1-METHOXY-4-METHYLBENZENE AKA ( 4-METHYLANISOLE )
  • 4-METHYLANISOLE 99%
  • 32) PARA CRESYL METHYL ETHER
  • methylphenoxide
  • 4-Methylanisole,99%
  • p-Cresyl methyl eth
  • 4-Methylanisole, 99% 250GR
  • 4-Methylanisole, 99% 5GR
  • METH PARA CRESOL
  • 4-Cresolmethylether
  • 4-methoxy-toluen
  • 4-Methyl-1-methoxybenzene
  • 4-methylmethoxybenzene
  • 4-Methylphenol methyl ether
  • 4-methylphenolmethylether
  • 4-METHYLANISOLE FOR SYNTHESIS
  • p-Cresol Methyl Ether 4-Methylanisole
  • 4-Methylanisole (MSO)
  • MSO)4-Methylan
  • Anisole, p-methyl-
  • Benzene,1-methoxy-4-methyl-
  • femanumber2681
  • methoxy-1methyl-4benzene
  • Methyl 4-methylphenyl ether
  • Methyl p-cresyl ether
  • Methyl p-methylphenyl ether
  • methyl-para-cresol
  • methylpara-cresol
  • para-methoxytoluene
  • para-methyl anisol
  • para-methylanisole
  • p-Methylanisol
  • p-methyl-anisol
  • p-Tolyl methyl ether
  • p-tolylmethylether
  • 4-Methylanizole
  • 4-Methoxytoluene&gt
  • Moxifloxacin Imp.Y
  • 4-Methylanisole USP/EP/BP
  • Para Cresyl Methyl Ether (PCME)