ChemicalBook > CAS DataBase List > Hydroxy-PEG5-acid
Hydroxy-PEG5-acid
- Product Name
- Hydroxy-PEG5-acid
- CAS No.
- 2079768-50-4
- Chemical Name
- Hydroxy-PEG5-acid
- Synonyms
- HO-PEG5-CH2CH2COOH;Hydroxy-PEG5-propionic acid;1-Hydroxy-3,6,9,12,15-pentaoxaoctadecan-18-oic acid;Propanoic acid, 3-[(14-hydroxy-3,6,9,12-tetraoxatetradec-1-yl)oxy]-;HO-PEG5-CH2CH2COOH/Propanoic acid, 3-[(14-hydroxy-3,6,9,12-tetraoxatetradec-1-yl)oxy]-
- CBNumber
- CB03373635
- Molecular Formula
- C13H26O8
- Formula Weight
- 310.34
- MOL File
- 2079768-50-4.mol
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Hydroxy-PEG5-acid Property
- Boiling point:
- 455.7±45.0 °C(Predicted)
- Density
- 1.162±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- pka
- 4.28±0.10(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
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Hydroxy-PEG5-acid Chemical Properties,Usage,Production
Description
Hydroxy-PEG5-acid is a PEG derivative containing a hydroxyl group with a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Uses
Hydroxy-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Hydroxy-PEG5-acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Hydroxy-PEG5-acid manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Hydroxy-PEG5-acid 2079768-50-4
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-25
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