ChemicalBook > CAS DataBase List > N-Boc-PEG4-bromide

N-Boc-PEG4-bromide

Product Name
N-Boc-PEG4-bromide
CAS No.
1392499-32-9
Chemical Name
N-Boc-PEG4-bromide
Synonyms
BocNH-PEG4-Br;Br-PEG4-NHBoc;N-Boc-PEG4-bromide;N-Boc-PEG5-bromide;BocNH-PEG4-CH2CH2Br;N-Boc-PEG4-bromide N-Boc-;tert-butyl (14-bromo-3,6,9,12-tetraoxatetradecyl)carbamate;tert-butyl N-[2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]ethyl]carbamate;5,8,11,14-Tetraoxa-2-azahexadecanoic acid, 16-bromo-, 1,1-dimethylethyl ester;ADC,antibody-drug,PROTAC Linkers,ADC Linkers,N-Boc-PEG-5-bromide,cleavable,inhibit,conjugates,Inhibitor,N Boc PEG5 bromide,NBocPEG5bromide,Antibody-drug conjugates linkers
CBNumber
CB03373736
Molecular Formula
C15H30BrNO6
Formula Weight
400.31
MOL File
1392499-32-9.mol
More
Less

N-Boc-PEG4-bromide Property

Boiling point:
459.3±40.0 °C(Predicted)
Density 
1.223±0.06 g/cm3(Predicted)
solubility 
Soluble in DCM
pka
12.23±0.46(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

BroadPharm
Product number
BP-23789
Product name
N-Boc-PEG4-bromide
Purity
98%
Packaging
250mg
Price
$540
Updated
2021/12/16
Activate Scientific
Product number
AS103627
Product name
BocNH-PEG4-CH2CH2Br
Purity
95+%
Packaging
1g
Price
$665
Updated
2021/12/16
AK Scientific
Product number
0954EB
Product name
N-Boc-PEG5-bromide
Packaging
1g
Price
$856
Updated
2021/12/16
Crysdot
Product number
CD64000172
Product name
N-BOc-peg4-bromide
Purity
95%
Packaging
1g
Price
$600
Updated
2021/12/16
Acrotein
Product number
AC-8220
Product name
BocNH-PEG4-CH2CH2Br
Purity
97%
Packaging
0.25g
Price
$220
Updated
2021/12/16
More
Less

N-Boc-PEG4-bromide Chemical Properties,Usage,Production

Description

N-Boc-PEG4-bromide is a PEG linker containing a bromide group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Biological Activity

N-Boc-PEG5-bromide is a PROTAC linker that belongs to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).

in vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Cleavable

PEGs

Alkyl/ether

N-Boc-PEG4-bromide Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

N-Boc-PEG4-bromide Suppliers

China 47 United States 6 Global 53
Zhejiang Rui 'ao Biological Technology Co.,LTD.
Tel
0573-82087565 18966369783
Email
sales@ruiaobio.com
Country
China
ProdList
628
Advantage
58
PharmaBlock Sciences (Nanjing),Inc.
Tel
400-0255188 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9900
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5877
Advantage
58
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1246
Advantage
55
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12308
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28820
Advantage
58
Hangzhou HanLai Biochemical Technology Co., Ltd.
Tel
0571-86101219 13675881727
Fax
-
Email
sales@leobiochem.com
Country
China
ProdList
433
Advantage
58
Aikon International Limited
Tel
025-66028182 18112977050
Fax
(3)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
15820
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4824
Advantage
58
Shanghai Moss Medicine Technology Co., Ltd.
Tel
+86-188369842 +86-15618151133
Fax
QQ188369842
Email
188369842@qq.com
Country
China
ProdList
1945
Advantage
58
Shanghai UCHEM Inc.
Tel
+862156762820 +86-13564624040
Email
sales@myuchem.com
Country
China
ProdList
6841
Advantage
58
Hangzhou Huarong Pharm Co., Ltd.
Tel
571-86758373 +8613588754946
Fax
0086-571-81131109
Email
sales@huarongpharm.com
Country
CHINA
ProdList
3149
Advantage
58
Wuhan Borenpharm Co., Ltd
Tel
027-65563561 18717150066
Fax
027-59218822
Email
3207347307@qq.com
Country
CHINA
ProdList
1238
Advantage
58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
Tel
029-86217788 13892832556
Email
2440688701@qq.com
Country
China
ProdList
1992
Advantage
58
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Email
sales@accelachem.com
Country
China
ProdList
11728
Advantage
58
Shaanxi borno biotechnology co., LTD
Tel
+86-13759708231
Email
asherw9@hotmail.com
Country
China
ProdList
2351
Advantage
58
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD
Tel
025-86755008 17751752005
Fax
025-86755228
Email
hszhang@bestfluorodrug.com
Country
China
ProdList
2358
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49323
Advantage
58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tel
+86-021-61551413 +8618813727289
Email
contact@trustwe.com
Country
China
ProdList
5738
Advantage
58
Advanced chemblocks inc
Tel
650-6922368
Email
sales@achemblock.com
Country
China
ProdList
2992
Advantage
58
Zhengzhou Convergence Chemical Co. LTD
Tel
0371-53736046 13393710386
Fax
QQ:2853979814
Email
2853979814@qq.com
Country
China
ProdList
10005
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44486
Advantage
58
Zhengzhou Akem Chemical Co., Ltd
Tel
13303867194
Email
3001317055@qq.com
Country
China
ProdList
9626
Advantage
58
Nanjing Yili Biotechnology Co., Ltd.
Tel
18061293607
Email
2880300874@qq.com
Country
China
ProdList
8142
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
39997
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Email
product02@bidepharm.com
Country
China
ProdList
63720
Advantage
58
Shanghai Hansi Chemical Industry Co., Ltd.
Tel
17717618050
Email
zllg@gh-reagent.com
Country
China
ProdList
10424
Advantage
58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-80514535 19917294565
Email
et@chemextension.com
Country
China
ProdList
5061
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24017
Advantage
58
Changzhou Ruikaijia polymer material Technology Co., LTD
Tel
3693241975
Email
kairuijiabio@126.com
Country
China
ProdList
6526
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50471
Advantage
58
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD
Tel
025-86755008 17751752005
Email
hszhang@bestfluorodrug.com
Country
China
ProdList
2702
Advantage
58
Nanjing Tengyi Biotechnology Co., Ltd
Tel
025-58851786 17714337195
Email
sales@tybiochem.com
Country
China
ProdList
5449
Advantage
58
Shanghai Jieshikai Biotechnology Co. , Ltd.
Tel
021-57520305 15221441005
Email
wangkang@jskchem.com
Country
China
ProdList
49242
Advantage
58
Shanghai Jiahua Herong Biotechnology Co., Ltd
Tel
13296077563 13296077563
Email
hr@bettersyn.com
Country
China
ProdList
9937
Advantage
58
Shanghai Titan Enterprise Development Co., Ltd
Tel
18817446984
Email
syy@titansci.com
Country
China
ProdList
2779
Advantage
58
shanghai yayu biomedical co.,ltd
Tel
021-54370211 18051886391
Email
3007215920@qq.com
Country
China
ProdList
2991
Advantage
58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
+86-18521732826
Email
market@aladdin-e.com
Country
China
ProdList
48467
Advantage
58
Chengdu Grimet Pharmaceutical Technology Co., Ltd
Tel
17308078590
Email
3796819867@qq.com
Country
China
ProdList
311
Advantage
58
Jilin Chinese Academy of Sciences-yanshen Technology
Tel
18143011203
Email
ET-market@chemextension.com
Country
China
ProdList
40873
Advantage
58
Xi‘an Deeptech Biotechnology Co.,LTD
Tel
15114901355
Email
15114901355@163.com
Country
China
ProdList
183
Advantage
58
Suzhou ARTK Medchem Co., Ltd.
Tel
+8618168183658
Email
sales1@artkmedchem.com
Country
China
ProdList
39009
Advantage
58
Xian confluore Biological Technology Co., Ltd.
Tel
+86-15680926068 +86-15680926068
Email
1924344760@confluore.cn
Country
China
ProdList
2996
Advantage
58
Jilin Chinese Academy of Sciences-yanshen Technology
Tel
+undefined18143011203
Email
info@chemextension.com
Country
China
ProdList
42057
Advantage
58
Shanghai Acmec Biochemical Technology Co., Ltd.
Tel
+undefined18621343501
Email
product@acmec-e.com
Country
China
ProdList
33350
Advantage
58
More
Less

View Lastest Price from N-Boc-PEG4-bromide manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Br-PEG4-NHBoc 1392499-32-9
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-25

1392499-32-9, N-Boc-PEG4-bromideRelated Search:

1,14-DIBROMO-3,6,9,12-TETRAOXATETRADECANE NA 1-Bromobutane Sulfanilamide N-ACETYLLACTOSAMINE 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol t-Boc-N-amido-PEG5-acid O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL) N-Boc-PEG5-alcohol Biotin-PEG36-PFP ester N-(Amino-PEG3)-N-bis(PEG4-Boc) BocNH-PEG5-acid Biotin-PEG6-t-butyl ester FMOC-18-AMINO-4,7,10,13,16-PENTAOXAOCTADECANOIC ACID 2-[2-[2-T-BOC-AMINOETHOXY]ETHOXY]ETHYL BROMIDE t-Boc-Aminooxy-PEG2-CH2CO2H N-(Amino-PEG4)-N-bis(PEG4-t-butyl ester) Mal-amido-PEG7-acid

  • N-Boc-PEG4-bromide
  • BocNH-PEG4-CH2CH2Br
  • N-Boc-PEG5-bromide
  • Br-PEG4-NHBoc
  • 5,8,11,14-Tetraoxa-2-azahexadecanoic acid, 16-bromo-, 1,1-dimethylethyl ester
  • tert-butyl (14-bromo-3,6,9,12-tetraoxatetradecyl)carbamate
  • ADC,antibody-drug,PROTAC Linkers,ADC Linkers,N-Boc-PEG-5-bromide,cleavable,inhibit,conjugates,Inhibitor,N Boc PEG5 bromide,NBocPEG5bromide,Antibody-drug conjugates linkers
  • tert-butyl N-[2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]ethyl]carbamate
  • N-Boc-PEG4-bromide N-Boc-
  • BocNH-PEG4-Br
  • 1392499-32-9
  • C15H30BrNO6