ChemicalBook > CAS DataBase List > Propargyl-PEG10-amine

Propargyl-PEG10-amine

Product Name
Propargyl-PEG10-amine
CAS No.
2112737-25-2
Chemical Name
Propargyl-PEG10-amine
Synonyms
NH2-PEG10-Propargyl;Propargyl-PEG10-NH2;Propargyl-PEG10-amine;3,6,9,12,15,18,21,24,27,30-Decaoxatritriacont-32-yn-1-amine;Propargyl-PEG10-NH2/3,6,9,12,15,18,21,24,27,30-Decaoxatritriacont-32-yn-1-amine
CBNumber
CB03373756
Molecular Formula
C23H45NO10
Formula Weight
495.6
MOL File
2112737-25-2.mol
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Propargyl-PEG10-amine Property

Boiling point:
545.5±45.0 °C(Predicted)
Density 
1.079±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, sealed storage, away from moisture and light
form 
Liquid
pka
8.74±0.10(Predicted)
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23637
Product name
Propargyl-PEG10-amine
Purity
98%
Packaging
100mg
Price
$280
Updated
2021/12/16
Activate Scientific
Product number
AS104195
Product name
Propargyl-PEG10-NH2
Purity
95+%
Packaging
1g
Price
$787
Updated
2021/12/16
Acrotein
Product number
B-1148
Product name
Propargyl-PEG10-NH2
Purity
97%
Packaging
0.25g
Price
$293.34
Updated
2021/12/16
Acrotein
Product number
B-1148
Product name
Propargyl-PEG10-NH2
Purity
97%
Packaging
0.5g
Price
$440
Updated
2021/12/16
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Propargyl-PEG10-amine Chemical Properties,Usage,Production

Description

Propargyl-PEG10-amine is a PEG reagent that is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The propargyl group enables Click Chemistry reactions with azide-bearing compounds or biomolecules; copper catalyst is required.

Uses

Propargyl-PEG10-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG10-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] Guangrong Zheng, et al. Bcl-2 proteins degraders for cancer treatment. WO2019144117A1.

Propargyl-PEG10-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG10-amine Suppliers

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
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0431-0431-80514535 19917294565
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CHENGDU YINGNUOLING PHARMACEUTICAL TECHNOLOGY CO.,LTD
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Jilin Chinese Academy of Sciences-yanshen Technology
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View Lastest Price from Propargyl-PEG10-amine manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG10-amine 2112737-25-2
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-26

2112737-25-2, Propargyl-PEG10-amineRelated Search:


  • Propargyl-PEG10-amine
  • Propargyl-PEG10-NH2
  • 3,6,9,12,15,18,21,24,27,30-Decaoxatritriacont-32-yn-1-amine
  • Propargyl-PEG10-NH2/3,6,9,12,15,18,21,24,27,30-Decaoxatritriacont-32-yn-1-amine
  • NH2-PEG10-Propargyl
  • 2112737-25-2
  • C23H45NO10