ChemicalBook > CAS DataBase List > 2-Acetamidophenol

2-Acetamidophenol

Product Name
2-Acetamidophenol
CAS No.
614-80-2
Chemical Name
2-Acetamidophenol
Synonyms
NSC 398;NSC 3989;2-Acetamino;AKOS BBB/377;O AcetaMinophen;acetoaminophenol;O-ACETAMINOPHENOL;O-ACETAMIDOPHENOL;2-ACETAMIDOPHENOL;2-acetamido-pheno
CBNumber
CB0342159
Molecular Formula
C8H9NO2
Formula Weight
151.16
MOL File
614-80-2.mol
More
Less

2-Acetamidophenol Property

Melting point:
205-210 °C(lit.)
Boiling point:
273.17°C (rough estimate)
Density 
1.2023 (rough estimate)
refractive index 
1.5810 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Powder
pka
9.35±0.35(Predicted)
color 
Off-white to beige to brown
BRN 
607592
Stability:
Stable. Incompatible with strong oxidizing agents, chloroformates, acids, acid chlorides, acid anhydrides.
CAS DataBase Reference
614-80-2(CAS DataBase Reference)
NIST Chemistry Reference
Acetamide, N-(2-hydroxyphenyl)-(614-80-2)
EPA Substance Registry System
2'-Hydroxyacetanilide (614-80-2)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/38-22-36/37/38
Safety Statements 
26-36-37/39
RIDADR 
2811
WGK Germany 
3
RTECS 
AE4025000
F 
1-8
TSCA 
Yes
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29242995
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A7000
Product name
2-Acetamidophenol
Purity
97%
Packaging
25g
Price
$48.7
Updated
2024/03/01
Sigma-Aldrich
Product number
A7000
Product name
2-Acetamidophenol
Purity
97%
Packaging
100g
Price
$90.1
Updated
2024/03/01
Sigma-Aldrich
Product number
1003031
Product name
Acetaminophen Related Compound C
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$1380
Updated
2024/03/01
TCI Chemical
Product number
H0189
Product name
2'-Hydroxyacetanilide
Purity
>99.0%(HPLC)(N)
Packaging
25g
Price
$68
Updated
2024/03/01
Alfa Aesar
Product number
B21264
Product name
2-Acetamidophenol, 97%
Packaging
25g
Price
$22.65
Updated
2024/03/01
More
Less

2-Acetamidophenol Chemical Properties,Usage,Production

Chemical Properties

white or light brown powder.soluble in hot water and ethanol, slightly soluble in cold water.

Uses

An Acetaminophen (A161220) impurity.
2-Acetamidophenol is used as raw material to manufacture industrial organic chemicals.
Acetaminophen is an analgesic and antipyretic agent and used as a pain reliever to treat headache, muscle aches, and arthritis.

Definition

ChEBI: 2-acetamidophenol is a member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties. It has a role as a platelet aggregation inhibitor, an anti-inflammatory agent, a xenobiotic metabolite, an apoptosis inducer, an antineoplastic agent and an antirheumatic drug. It is a member of phenols and a member of acetamides.

Preparation

Mix 2-Aminophenol , acetic acid and Acetic anhydride (i.e., crystals appear), and then directly heated on the fire until all dissolved, stop heating, cooling, water dilution, precipitation of crystals filtered dry, to 70-80 ℃ of ethanol recrystallization to obtain 2-acetamidophenol.

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Purification Methods

Recrystallise it from water, EtOH or Est aqueous EtOH. [Beilstein 13 H 370, 13 I 113, 13 II 171, 13 III 778.]

2-Acetamidophenol Preparation Products And Raw materials

Raw materials

2-Aminophenol

Preparation Products

More
Less

2-Acetamidophenol Suppliers

Americas 1 Belgium 1 Canada 2 China 200 Europe 4 Germany 5 India 41 Japan 5 Russia 1 Slovakia 1 Switzerland 2 United Kingdom 18 United States 38 Global 319
Pushan Industry (Shaanxi) Co., Ltd.
Tel
029-81310890 13571859809
Email
info@pushanshiye.com
Country
China
ProdList
10003
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1998
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Yangzhou Aoxin Chemical Co., Ltd
Tel
0514-87754778 13901446058
Fax
+86-514-87752291
Email
sales@aochem.com
Country
China
ProdList
73
Advantage
66
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-0712-2580635 15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7815
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 15343847665
Fax
QQ：3470079902
Email
huawenchem@163.com
Country
China
ProdList
3206
Advantage
55
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9725
Advantage
55
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
4993
Advantage
50
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-83725681-603
Fax
+86 755 28094224
Country
China
ProdList
4505
Advantage
50
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9872
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Beijing Comparison Pharmaceutical Technology Co., Ltd
Tel
010-52878169 15701683040
Email
sales@bjcomparison.com
Country
China
ProdList
4671
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19918
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
Shanghai Meishui Chemical Technology Co., Ltd
Tel
021-60549325 18616193163
Fax
021-33250306
Country
China
ProdList
4528
Advantage
56
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9986
Advantage
55
Huainan Kedi Chemical Factory
Tel
0554-2106669
Fax
0554-2666215
Email
sales1@kedichem.com
Country
China
ProdList
4928
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai DiBai Chemicals Co., Ltd.
Tel
021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3993
Advantage
60
Zhengzhou HongSheng Pharmaceutical Co., Ltd.
Tel
1352-6885213 15637198702
Fax
0371-63709726
Email
xpkchem@163.com
Country
China
ProdList
3998
Advantage
58
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9353
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17982
Advantage
56
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5223
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15878
Advantage
55
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9911
Advantage
50
Hangzhou J&H Chemical Co., Ltd.
Tel
+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
10015
Advantage
53
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6490
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-58362220 15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7715
Advantage
55
Giant chemicals
Tel
028-85434334 18108076537
Fax
QQ：245797092
Email
market@gianthx.com
Country
China
ProdList
4512
Advantage
56
More
Less

View Lastest Price from 2-Acetamidophenol manufacturers

Hebei Guanlang Biotechnology Co., Ltd.
Product
2-Acetamidophenol 614-80-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2023-02-28
Hebei Mojin Biotechnology Co., Ltd
Product
2-Acetamidophenol 614-80-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-17
Hebei Guanlang Biotechnology Co., Ltd.
Product
2-Acetamidophenol 614-80-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2022-11-16

614-80-2, 2-AcetamidophenolRelated Search:

4'-Aminoacetanilide 4'-Nitroacetanilide Acetamide 4-Hydroxyaniline hydrochloride 3-Diethylaminophenol p-Acetotoluidide 2-BENZOYLACETANILIDE 2-ACETAMIDOFLUORENE 4-Aminophenol 2-Aminophenol 2-Chloro-4-acetamidophenol ACETAMINOPHEN IMPURITY B 4'-CHLOROACETANILIDE 4-[1-(hydroxyamino)ethylidene]cyclohexa-2,5-dien-1-one 4,4'-Iminodiphenol hydrochloride 4'-Hydroxyacetophenone 2'-Hydroxyacetophenone 4-Acetoxyacetanilide

  • 2-ACETYLAMINOPHENOL
  • 2-ACETAMIDOPHENOL
  • 2-ACETAMINO PHENOL
  • Acetaminophen Related Compound C (50 mg) (N-(2-hydroxyphenyl)acetamide)
  • AKOS BBB/377
  • O-HYDROXYACETANILIDE
  • O-ACETAMIDOPHENOL
  • O-ACETAMINOPHENOL
  • N-(2-Hydroxyphenyl)acetamide
  • 2'-HYDROXYACETANILIDE
  • 2-HYDROXYACETANILIDE
  • 2’-hydroxy-acetanilid
  • 2-acetamido-pheno
  • 2-Hydroxyanilid kyseliny octove
  • 2-hydroxyanilidkyselinyoctove
  • Acetanilide, 2'-hydroxy-
  • Acet-o-aminofenol
  • n-(2-hydroxyphenyl)-acetamid
  • N-(2-hydroxyphenyl)ethanamide
  • N-Acetyl-2-aminophenol
  • N-Acetyl-o-aminophenol
  • o-(Acetylamino)phenol
  • o-Acetylaminofenol
  • Phenol, 2-acetamido-
  • Paracetamol EP Impurity A(2-Acetamidophenol)
  • 2-Acetamidophenol99%
  • 2-Acetamidophenol,97%
  • 2-(N-Acetylamino)phenol
  • NSC 398
  • 2-Acetamino
  • o-Acetamidophenol AP
  • ORTHO-HYDROXYACETANILIDE
  • 2-HYDROXYACETANILIDE / 2-ACETAMIDOPHENOL
  • NSC 3989
  • o-Aminophenol N-acetate
  • 2-Acetamide phenol
  • O AcetaMinophen
  • ParacetaMol IMpurity A
  • 2-AcetaMidophenol, 98.5%
  • AcetaMinophen Related CoMpound C
  • Paracetamol EP Impurity A
  • Paracetamol Impurity 1(Paracetamol EP Impurity A)
  • 2'-Hydroxyacetanilide&gt
  • N-(2-Hydroxyphenyl)acetamide (2-Ace
  • Acetamide, N-(2-hydroxyphenyl)-
  • acetoaminophenol
  • Paracetamol(Acetaminophen) EP Impurity A
  • Paracetamol EP Impurity
  • Acetaminophen related compound C Paracetamol Impurity A
  • Acetaminophen impurities1455
  • Acetaminophen EP Impurity A
  • Acetaminophen Related Compound C (R00920)
  • Acetaminophen Related Compound C (N-(2-hydroxyphenyl)acetamide) (1003031)
  • Acetaminophen USP Related Compound C
  • 2 Acetamidophenol,2Acetamidophenol
  • Paracetamol EP Impurity A (Acetaminophen USP Related Compound C)
  • Paracetamol EP Impurity A N-(2-hydroxyphenyl)acetamide
  • 2'-Hydroxyacetanilide, ≥ 99.0%