ChemicalBook > CAS DataBase List > 2-Acetamidophenol

2-Acetamidophenol

Product Name
2-Acetamidophenol
CAS No.
614-80-2
Chemical Name
2-Acetamidophenol
Synonyms
NSC 398;NSC 3989;2-Acetamino;AKOS BBB/377;O AcetaMinophen;acetoaminophenol;O-ACETAMINOPHENOL;O-ACETAMIDOPHENOL;2-ACETAMIDOPHENOL;2-acetamido-pheno
CBNumber
CB0342159
Molecular Formula
C8H9NO2
Formula Weight
151.16
MOL File
614-80-2.mol
More
Less

2-Acetamidophenol Property

Melting point:
205-210 °C(lit.)
Boiling point:
273.17°C (rough estimate)
Density 
1.2023 (rough estimate)
refractive index 
1.5810 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Powder
pka
9.35±0.35(Predicted)
color 
Off-white to beige to brown
BRN 
607592
Stability:
Stable. Incompatible with strong oxidizing agents, chloroformates, acids, acid chlorides, acid anhydrides.
CAS DataBase Reference
614-80-2(CAS DataBase Reference)
NIST Chemistry Reference
Acetamide, N-(2-hydroxyphenyl)-(614-80-2)
EPA Substance Registry System
2'-Hydroxyacetanilide (614-80-2)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/38-22-36/37/38
Safety Statements 
26-36-37/39
RIDADR 
2811
WGK Germany 
3
RTECS 
AE4025000
1-8
TSCA 
Yes
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29242995
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A7000
Product name
2-Acetamidophenol
Purity
97%
Packaging
25g
Price
$48.7
Updated
2024/03/01
Sigma-Aldrich
Product number
A7000
Product name
2-Acetamidophenol
Purity
97%
Packaging
100g
Price
$90.1
Updated
2024/03/01
Sigma-Aldrich
Product number
1003031
Product name
Acetaminophen Related Compound C
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$1380
Updated
2024/03/01
TCI Chemical
Product number
H0189
Product name
2'-Hydroxyacetanilide
Purity
>99.0%(HPLC)(N)
Packaging
25g
Price
$68
Updated
2024/03/01
Alfa Aesar
Product number
B21264
Product name
2-Acetamidophenol, 97%
Packaging
25g
Price
$22.65
Updated
2024/03/01
More
Less

2-Acetamidophenol Chemical Properties,Usage,Production

Chemical Properties

white or light brown powder.soluble in hot water and ethanol, slightly soluble in cold water.

Uses

An Acetaminophen (A161220) impurity.
2-Acetamidophenol is used as raw material to manufacture industrial organic chemicals.
Acetaminophen is an analgesic and antipyretic agent and used as a pain reliever to treat headache, muscle aches, and arthritis.

Definition

ChEBI: 2-acetamidophenol is a member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties. It has a role as a platelet aggregation inhibitor, an anti-inflammatory agent, a xenobiotic metabolite, an apoptosis inducer, an antineoplastic agent and an antirheumatic drug. It is a member of phenols and a member of acetamides.

Preparation

Mix 2-Aminophenol , acetic acid and Acetic anhydride (i.e., crystals appear), and then directly heated on the fire until all dissolved, stop heating, cooling, water dilution, precipitation of crystals filtered dry, to 70-80 ℃ of ethanol recrystallization to obtain 2-acetamidophenol.

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Purification Methods

Recrystallise it from water, EtOH or Est aqueous EtOH. [Beilstein 13 H 370, 13 I 113, 13 II 171, 13 III 778.]

2-Acetamidophenol Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-Acetamidophenol Suppliers

Pushan Industry (Shaanxi) Co., Ltd.
Tel
029-81310890 13571859809
Email
info@pushanshiye.com
Country
China
ProdList
10002
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1998
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Yangzhou Aoxin Chemical Co., Ltd
Tel
0514-87754778 13901446058
Fax
+86-514-87752291
Email
sales@aochem.com
Country
China
ProdList
73
Advantage
66
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
More
Less

View Lastest Price from 2-Acetamidophenol manufacturers

Hebei Guanlang Biotechnology Co., Ltd.
Product
2-Acetamidophenol 614-80-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2023-02-28
Hebei Mojin Biotechnology Co., Ltd
Product
2-Acetamidophenol 614-80-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-17
Hebei Guanlang Biotechnology Co., Ltd.
Product
2-Acetamidophenol 614-80-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2022-11-16

614-80-2, 2-AcetamidophenolRelated Search:


  • 2-ACETYLAMINOPHENOL
  • 2-ACETAMIDOPHENOL
  • 2-ACETAMINO PHENOL
  • Acetaminophen Related Compound C (50 mg) (N-(2-hydroxyphenyl)acetamide)
  • AKOS BBB/377
  • O-HYDROXYACETANILIDE
  • O-ACETAMIDOPHENOL
  • O-ACETAMINOPHENOL
  • N-(2-Hydroxyphenyl)acetamide
  • 2'-HYDROXYACETANILIDE
  • 2-HYDROXYACETANILIDE
  • 2’-hydroxy-acetanilid
  • 2-acetamido-pheno
  • 2-Hydroxyanilid kyseliny octove
  • 2-hydroxyanilidkyselinyoctove
  • Acetanilide, 2'-hydroxy-
  • Acet-o-aminofenol
  • n-(2-hydroxyphenyl)-acetamid
  • N-(2-hydroxyphenyl)ethanamide
  • N-Acetyl-2-aminophenol
  • N-Acetyl-o-aminophenol
  • o-(Acetylamino)phenol
  • o-Acetylaminofenol
  • Phenol, 2-acetamido-
  • Paracetamol EP Impurity A(2-Acetamidophenol)
  • 2-Acetamidophenol99%
  • 2-Acetamidophenol,97%
  • 2-(N-Acetylamino)phenol
  • NSC 398
  • 2-Acetamino
  • o-Acetamidophenol AP
  • ORTHO-HYDROXYACETANILIDE
  • 2-HYDROXYACETANILIDE / 2-ACETAMIDOPHENOL
  • NSC 3989
  • o-Aminophenol N-acetate
  • 2-Acetamide phenol
  • O AcetaMinophen
  • ParacetaMol IMpurity A
  • 2-AcetaMidophenol, 98.5%
  • AcetaMinophen Related CoMpound C
  • Paracetamol EP Impurity A
  • Paracetamol Impurity 1(Paracetamol EP Impurity A)
  • 2'-Hydroxyacetanilide&gt
  • N-(2-Hydroxyphenyl)acetamide (2-Ace
  • Acetamide, N-(2-hydroxyphenyl)-
  • acetoaminophenol
  • Paracetamol(Acetaminophen) EP Impurity A
  • Paracetamol EP Impurity
  • Acetaminophen related compound C Paracetamol Impurity A
  • Acetaminophen impurities1455
  • Acetaminophen EP Impurity A
  • Acetaminophen Related Compound C (R00920)
  • Acetaminophen Related Compound C (N-(2-hydroxyphenyl)acetamide) (1003031)
  • Acetaminophen USP Related Compound C
  • 2 Acetamidophenol,2Acetamidophenol
  • Paracetamol EP Impurity A (Acetaminophen USP Related Compound C)
  • Paracetamol EP Impurity A N-(2-hydroxyphenyl)acetamide
  • 2'-Hydroxyacetanilide, ≥ 99.0%