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2-Acetamidophenol

Product Name
2-Acetamidophenol
CAS No.
614-80-2
Chemical Name
2-Acetamidophenol
Synonyms
NSC 398;NSC 3989;2-Acetamino;AKOS BBB/377;O AcetaMinophen;acetoaminophenol;O-ACETAMINOPHENOL;O-ACETAMIDOPHENOL;2-ACETAMIDOPHENOL;2-acetamido-pheno
CBNumber
CB0342159
Molecular Formula
C8H9NO2
Formula Weight
151.16
MOL File
614-80-2.mol
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2-Acetamidophenol Property

Melting point:
205-210 °C(lit.)
Boiling point:
273.17°C (rough estimate)
Density 
1.2023 (rough estimate)
refractive index 
1.5810 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Powder
pka
9.35±0.35(Predicted)
color 
Off-white to beige to brown
BRN 
607592
Stability:
Stable. Incompatible with strong oxidizing agents, chloroformates, acids, acid chlorides, acid anhydrides.
CAS DataBase Reference
614-80-2(CAS DataBase Reference)
NIST Chemistry Reference
Acetamide, N-(2-hydroxyphenyl)-(614-80-2)
EPA Substance Registry System
2'-Hydroxyacetanilide (614-80-2)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/38-22-36/37/38
Safety Statements 
26-36-37/39
RIDADR 
2811
WGK Germany 
3
RTECS 
AE4025000
1-8
TSCA 
Yes
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29242995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A7000
Product name
2-Acetamidophenol
Purity
97%
Packaging
25g
Price
$48.7
Updated
2024/03/01
Sigma-Aldrich
Product number
A7000
Product name
2-Acetamidophenol
Purity
97%
Packaging
100g
Price
$90.1
Updated
2024/03/01
Sigma-Aldrich
Product number
1003031
Product name
Acetaminophen Related Compound C
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$1380
Updated
2024/03/01
TCI Chemical
Product number
H0189
Product name
2'-Hydroxyacetanilide
Purity
>99.0%(HPLC)(N)
Packaging
25g
Price
$68
Updated
2024/03/01
Alfa Aesar
Product number
B21264
Product name
2-Acetamidophenol, 97%
Packaging
25g
Price
$22.65
Updated
2024/03/01
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2-Acetamidophenol Chemical Properties,Usage,Production

Chemical Properties

white or light brown powder.soluble in hot water and ethanol, slightly soluble in cold water.

Uses

An Acetaminophen (A161220) impurity.
2-Acetamidophenol is used as raw material to manufacture industrial organic chemicals.
Acetaminophen is an analgesic and antipyretic agent and used as a pain reliever to treat headache, muscle aches, and arthritis.

Definition

ChEBI: 2-acetamidophenol is a member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties. It has a role as a platelet aggregation inhibitor, an anti-inflammatory agent, a xenobiotic metabolite, an apoptosis inducer, an antineoplastic agent and an antirheumatic drug. It is a member of phenols and a member of acetamides.

Preparation

Mix 2-Aminophenol , acetic acid and Acetic anhydride (i.e., crystals appear), and then directly heated on the fire until all dissolved, stop heating, cooling, water dilution, precipitation of crystals filtered dry, to 70-80 ℃ of ethanol recrystallization to obtain 2-acetamidophenol.

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Purification Methods

Recrystallise it from water, EtOH or Est aqueous EtOH. [Beilstein 13 H 370, 13 I 113, 13 II 171, 13 III 778.]

2-Acetamidophenol Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Acetamidophenol Suppliers

TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23680
Advantage
75
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View Lastest Price from 2-Acetamidophenol manufacturers

Hebei Guanlang Biotechnology Co., Ltd.
Product
2-Acetamidophenol 614-80-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2023-02-28
Hebei Mojin Biotechnology Co., Ltd
Product
2-Acetamidophenol 614-80-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-17
Hebei Guanlang Biotechnology Co., Ltd.
Product
2-Acetamidophenol 614-80-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2022-11-16

614-80-2, 2-AcetamidophenolRelated Search:


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  • 614-80-2