2-Acetamidophenol

Product Name: 2-Acetamidophenol
CAS No.: 614-80-2
Chemical Name: 2-Acetamidophenol
Synonyms: NSC 398;NSC 3989;2-Acetamino;AKOS BBB/377;O AcetaMinophen;acetoaminophenol;O-ACETAMINOPHENOL;O-ACETAMIDOPHENOL;2-ACETAMIDOPHENOL;2-acetamido-pheno
CBNumber: CB0342159
Molecular Formula: C8H9NO2
Formula Weight: 151.16
MOL File: 614-80-2.mol

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2-Acetamidophenol Property

Melting point:: 205-210 °C(lit.)
Boiling point:: 273.17°C (rough estimate)
Density: 1.2023 (rough estimate)
refractive index: 1.5810 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Powder
pka: 9.35±0.35(Predicted)
color: Off-white to beige to brown
BRN: 607592
Stability:: Stable. Incompatible with strong oxidizing agents, chloroformates, acids, acid chlorides, acid anhydrides.
InChI: InChI=1S/C8H9NO2/c1-6(10)9-7-4-2-3-5-8(7)11/h2-5,11H,1H3,(H,9,10)
InChIKey: ADVGKWPZRIDURE-UHFFFAOYSA-N
SMILES: C(NC1=CC=CC=C1O)(=O)C
CAS DataBase Reference: 614-80-2(CAS DataBase Reference)
NIST Chemistry Reference: Acetamide, N-(2-hydroxyphenyl)-(614-80-2)
EPA Substance Registry System: 2'-Hydroxyacetanilide (614-80-2)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/38-22-36/37/38
Safety Statements: 26-36-37/39
RIDADR: 2811
WGK Germany: 3
RTECS: AE4025000
F: 1-8
TSCA: Yes
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 29242995

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A7000
Product name: 2-Acetamidophenol
Purity: 97%
Packaging: 25g
Price: $48.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: A7000
Product name: 2-Acetamidophenol
Purity: 97%
Packaging: 100g
Price: $90.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1003031
Product name: Acetaminophen Related Compound C
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 50mg
Price: $1380
Updated: 2024/03/01

TCI Chemical

Product number: H0189
Product name: 2'-Hydroxyacetanilide
Purity: >99.0%(HPLC)(N)
Packaging: 25g
Price: $68
Updated: 2024/03/01

Alfa Aesar

Product number: B21264
Product name: 2-Acetamidophenol, 97%
Packaging: 25g
Price: $22.65
Updated: 2024/03/01

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2-Acetamidophenol Chemical Properties,Usage,Production

Chemical Properties

white or light brown powder.soluble in hot water and ethanol, slightly soluble in cold water.

Uses

An Acetaminophen (A161220) impurity.
2-Acetamidophenol is used as raw material to manufacture industrial organic chemicals.
Acetaminophen is an analgesic and antipyretic agent and used as a pain reliever to treat headache, muscle aches, and arthritis.

Definition

ChEBI: 2-acetamidophenol is a member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties. It has a role as a platelet aggregation inhibitor, an anti-inflammatory agent, a xenobiotic metabolite, an apoptosis inducer, an antineoplastic agent and an antirheumatic drug. It is a member of phenols and a member of acetamides.

Preparation

Mix 2-Aminophenol , acetic acid and Acetic anhydride (i.e., crystals appear), and then directly heated on the fire until all dissolved, stop heating, cooling, water dilution, precipitation of crystals filtered dry, to 70-80 ℃ of ethanol recrystallization to obtain 2-acetamidophenol.

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Purification Methods

Recrystallise it from water, EtOH or Est aqueous EtOH. [Beilstein 13 H 370, 13 I 113, 13 II 171, 13 III 778.]

2-Acetamidophenol Preparation Products And Raw materials

Raw materials

2-Aminophenol

Preparation Products

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2-Acetamidophenol Suppliers

Americas 1 Belgium 1 Canada 2 China 221 Europe 4 Germany 5 India 41 Japan 5 Russia 1 Slovakia 1 Switzerland 2 United Kingdom 18 United States 37 Global 339

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View Lastest Price from 2-Acetamidophenol manufacturers

Apeloa production Co.,Limited

Product: acetoaminophenol 614-80-2
Price: US $1.00/g
Min. Order: 1g
Purity: 0.98
Supply Ability: 1000
Release date: 2024-07-19

PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD

Product: 2-Acetamidophenol 614-80-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 2-5 MTs
Release date: 2024-05-11

Hebei Weibang Biotechnology Co., Ltd

Product: 2-Acetamidophenol 614-80-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-12-11

614-80-2, 2-AcetamidophenolRelated Search:

4'-Aminoacetanilide 4'-Nitroacetanilide Acetamide 4-Hydroxyaniline hydrochloride 3-Diethylaminophenol p-Acetotoluidide 2-BENZOYLACETANILIDE 2-ACETAMIDOFLUORENE 4-Aminophenol 2-Aminophenol 2-Chloro-4-acetamidophenol ACETAMINOPHEN IMPURITY B 4'-CHLOROACETANILIDE 4-[1-(hydroxyamino)ethylidene]cyclohexa-2,5-dien-1-one 4,4'-Iminodiphenol hydrochloride 4'-Hydroxyacetophenone 2'-Hydroxyacetophenone 4-Acetoxyacetanilide

2-ACETYLAMINOPHENOL

2-ACETAMIDOPHENOL

2-ACETAMINO PHENOL

Acetaminophen Related Compound C (50 mg) (N-(2-hydroxyphenyl)acetamide)

AKOS BBB/377

O-HYDROXYACETANILIDE

O-ACETAMIDOPHENOL

O-ACETAMINOPHENOL

N-(2-Hydroxyphenyl)acetamide

2'-HYDROXYACETANILIDE

2-HYDROXYACETANILIDE

2’-hydroxy-acetanilid

2-acetamido-pheno

2-Hydroxyanilid kyseliny octove

2-hydroxyanilidkyselinyoctove

Acetanilide, 2'-hydroxy-

Acet-o-aminofenol

n-(2-hydroxyphenyl)-acetamid

N-(2-hydroxyphenyl)ethanamide

N-Acetyl-2-aminophenol

N-Acetyl-o-aminophenol

o-(Acetylamino)phenol

o-Acetylaminofenol

Phenol, 2-acetamido-

Paracetamol EP Impurity A(2-Acetamidophenol)

2-Acetamidophenol99%

2-Acetamidophenol,97%

2-(N-Acetylamino)phenol

NSC 398

2-Acetamino

o-Acetamidophenol AP

ORTHO-HYDROXYACETANILIDE

2-HYDROXYACETANILIDE / 2-ACETAMIDOPHENOL

NSC 3989

o-Aminophenol N-acetate

2-Acetamide phenol

O AcetaMinophen

ParacetaMol IMpurity A

2-AcetaMidophenol, 98.5%

AcetaMinophen Related CoMpound C

Paracetamol EP Impurity A

Paracetamol Impurity 1(Paracetamol EP Impurity A)

2'-Hydroxyacetanilide&gt

N-(2-Hydroxyphenyl)acetamide (2-Ace

Acetamide, N-(2-hydroxyphenyl)-

acetoaminophenol

Paracetamol(Acetaminophen) EP Impurity A

Paracetamol EP Impurity

Acetaminophen related compound C Paracetamol Impurity A

Acetaminophen impurities1455

Acetaminophen EP Impurity A

Acetaminophen Related Compound C (R00920)

Acetaminophen Related Compound C (N-(2-hydroxyphenyl)acetamide) (1003031)

Acetaminophen USP Related Compound C

2 Acetamidophenol,2Acetamidophenol

2'-Hydroxyacetanilide, ≥ 99.0%

Acetaminophene Related Compound C

PARACETAMOL EP IMP A/Acetaminophen USP RC C